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· · COA & SDS Disponible para cada producto · Same-day shipping on in-stock items JNJ-40411813 - Moligand™, ≥98% , Metabotropic glutamate receptor 2 positive allosteric modulator, CAS No.1127498-03-6, Metabotropic glutamate receptor 2 positive allosteric modulator
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98% Synonyms
612BYT76F3 | MS-25297 | JNJ-40411813; ADX-71149 | Tox21_300488 | UNII-612BYT76F3 | SCHEMBL1035416 | CVB49803 | 1-butyl-3-chloro-4-(4-phenylpiperidin-1-yl)pyridin-2-one | ADX-71149ADX-71149 | EX-A2902 | JNJ-40411813; JNJ 40411813; ADX71149; ADX 71149; ADX-
Shipped In
Ice chest + Ice pads
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Why this grade Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Descripción general Information
JNJ-40411813 (ADX-71149) is a positive allosteric modulator (PAM) of the metabotropic Glutamate 2 receptor (mGlu2R) with EC50 of 147 nM.
Specifications Sinónimos
612BYT76F3 | MS-25297 | JNJ-40411813; ADX-71149 | Tox21_300488 | UNII-612BYT76F3 | SCHEMBL1035416 | CVB49803 | 1-butyl-3-chloro-4-(4-phenylpiperidin-1-yl)pyridin-2-one | ADX-71149ADX-71149 | EX-A2902 | JNJ-40411813; JNJ 40411813; ADX71149; ADX 71149; ADX-
Especificaciones y pureza
Moligand™, ≥98%
Mecanismos bioquímicos y fisiológicos
JNJ-40411813 (ADX-71149) is a positive allosteric modulator (PAM) of the metabotropic Glutamate 2 receptor (mGlu2R) with EC50 of 147 nM.
Condiciones de almacenamiento de almacenamiento
Store at -20°C
Enviado en
Ice chest + Ice pads
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Tipo de acción
ALLOSTERIC MODULATOR, POSITIVE ALLOSTERIC MODULATOR
Mecanismo de acción
Metabotropic glutamate receptor 2 positive allosteric modulator
Propiedades del producto Nombres e identificadores Sonrisas canónicas CCCCN1C=CC(=C(C1=O)Cl)N2CCC(CC2)C3=CC=CC=C3 IUPAC Name 1-butyl-3-chloro-4-(4-phenylpiperidin-1-yl)pyridin-2-one InChIKey HYOGJHCDLQSAHX-UHFFFAOYSA-N INCHI 1S/C20H25ClN2O/c1-2-3-12-23-15-11-18(19(21)20(23)24)22-13-9-17(10-14-22)16-7-5-4-6-8-16/h4-8,11,15,17H,2-3,9-10,12-14H2,1H3 Isómeros SMILES CCCCN1C=CC(=C(C1=O)Cl)N2CCC(CC2)C3=CC=CC=C3 Peso molecular 344.88 Reaxy-Rn 19071956 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=19071956&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Clase Piperidines Subclass Phenylpiperidines Intermediate Tree Nodes Not available Direct Parent Phenylpiperidines Alternative Parents Dialkylarylamines Pyridinones Dihydropyridines Aralkylamines Aminopyridines and derivatives Benzene and substituted derivatives Aryl chlorides Vinylogous amides Heteroaromatic compounds Lactams Azacyclic compounds Organooxygen compounds Organochlorides Organic oxides Hydrocarbon derivatives Molecular Framework Aromatic heteromonocyclic compounds Substituents Phenylpiperidine - Tertiary aliphatic/aromatic amine - Dialkylarylamine - Aminopyridine - Dihydropyridine - Pyridinone - Aralkylamine - Aryl chloride - Aryl halide - Monocyclic benzene moiety - Hydropyridine - Pyridine - Benzenoid - Heteroaromatic compound - Vinylogous amide - Lactam - Tertiary amine - Azacycle - Organic nitrogen compound - Organic oxide - Organooxygen compound - Organonitrogen compound - Organochloride - Organohalogen compound - Amine - Organic oxygen compound - Hydrocarbon derivative - Aromatic heteromonocyclic compound Descripción This compound belongs to the class of organic compounds known as phenylpiperidines. These are compounds containing a phenylpiperidine skeleton, which consists of a piperidine bound to a phenyl group. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Estructura 3D Objetivos asociados (humanos) Objetivos asociados (no humanos) Mecanismos de acción Certificados (CoA, COO, BSE/TSE y tabla de análisis) Propiedades químicas y físicas Peso molecular 344.900 g/mol XLogP3 4.600 Hydrogen Bond Donor Count 0 Hydrogen Bond Acceptor Count 2 Rotatable Bond Count 5 Exact Mass 344.166 Da Monoisotopic Mass 344.166 Da Topological Polar Surface Area 23.600 Ų Heavy Atom Count 24 Formal Charge 0 Complexity 500.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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