JTV 519 fumarate - ≥98% , CAS No.1883549-36-7

CAS: 1883549-36-7 Cat. No.: J275634 Peso molecular: 540.67 PubChem CID: 91826075
Disponible para pedir
GRADE & PURITY ≥98%
Synonyms
3-(4-Benzylpiperidin-1-yl)-1-(7-methoxy-3,5-dihydro-2H-1,4-benzothiazepin-4-yl)propan-1-one(E)-but-2-enedioicacid | 1-(2,3-Dihydro-7-methoxy-1,4-benzothiazepin-4(5H)-yl)-3-[4-(phenylmethyl)-1-piperidinyl]-1-propanone fumarate
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
1mg
J275634-1mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
129,90US$
5mg
J275634-5mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
259,90US$
10mg
J275634-10mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
459,90US$
25mg
J275634-25mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
999,90US$
50mg
J275634-50mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
1.599,90US$
Enter a quantity for the sizes you want to add.
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Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Product description
Ryanodine receptor (RyR) inhibitor; stabilizes RyR2 in a closed conformation. Exhibits antiarrhythmic and cardioprotective properties in vivo.

Specifications

Sinónimos
3-(4-Benzylpiperidin-1-yl)-1-(7-methoxy-3, 5-dihydro-2H-1, 4-benzothiazepin-4-yl)propan-1-one(E)-but-2-enedioicacid | 1-(2, 3-Dihydro-7-methoxy-1, 4-benzothiazepin-4(5H)-yl)-3-[4-(phenylmethyl)-1-piperidinyl]-1-propanone fumarate
Especificaciones y pureza
≥98%
Mecanismos bioquímicos y fisiológicos
Ca 2+ dependent blocker of SERCA and a partial agonist of ryanodine receptors (RyRs). Displays Ca 2+ -dependent inhibition of SERCA-dependent ATPase activity with IC 50 of 9µM at 0.25 Ca 2+ in cardiac muscle.
Condiciones de almacenamiento de almacenamiento
Store at -20°C
Enviado en
Ice chest + Ice pads
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Nota
Toxic, refer to SDS for further information. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Pureza
≥98%
Nombres e identificadores
Sonrisas canónicasCOC1=CC2=C(C=C1)SCCN(C2)C(=O)CCN3CCC(CC3)CC4=CC=CC=C4.C(=CC(=O)O)C(=O)O
IUPAC Name3-(4-benzylpiperidin-1-yl)-1-(7-methoxy-3,5-dihydro-2H-1,4-benzothiazepin-4-yl)propan-1-one;(E)-but-2-enedioic acid
InChIKeyISLOBKLDZGDFTB-WLHGVMLRSA-N
INCHI1S/C25H32N2O2S.C4H4O4/c1-29-23-7-8-24-22(18-23)19-27(15-16-30-24)25(28)11-14-26-12-9-21(10-13-26)17-20-5-3-2-4-6-20;5-3(6)1-2-4(7)8/h2-8,18,21H,9-17,19H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1+
Isómeros SMILES COC1=CC2=C(C=C1)SCCN(C2)C(=O)CCN3CCC(CC3)CC4=CC=CC=C4.C(=C/C(=O)O)\C(=O)O
CAS alternativo 145903-06-6(Free Base)
PubChem CID 91826075
Peso molecular 540.67

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Estructura 3D
Modelo de Estructura Química Interactiva





Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propiedades químicas y físicas
SensibilidadMoisture sensitive
Calculadoras de soluciones
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