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Moligand™, 10mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Protected from light,Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 15 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Kaempferide is a naturally occurring, O-methylated flavonol found in Kaempferia galanga. It exhibits a variety of pharmacological effects such as anti-inflammatory, anti-viral, anti-oxidant, anti-bacterial and antitumor properties.
Kaempferide is an O-methylated flavonol, a type of chemical compound. It can be found in Kaempferia galanga (aromatic ginger). The enzyme kaempferol 4'-O-methyltransferase uses S-adenosyl-L-methionine and kaempferol to produce S-adeno
| Sonrisas canónicas | COC1=CC=C(C=C1)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O |
|---|---|
| IUPAC Name | 3,5,7-trihydroxy-2-(4-methoxyphenyl)chromen-4-one |
| InChIKey | SQFSKOYWJBQGKQ-UHFFFAOYSA-N |
| INCHI | 1S/C16H12O6/c1-21-10-4-2-8(3-5-10)16-15(20)14(19)13-11(18)6-9(17)7-12(13)22-16/h2-7,17-18,20H,1H3 |
| Isómeros SMILES | COC1=CC=C(C=C1)C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O |
| WGK Alemania | 3 |
| RTECS | LK6915000 |
| Peso molecular | 300.26 |
| Beilstein | 305378 |
| Reaxy-Rn | 305378 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=305378&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Phenylpropanoids and polyketides |
| Clase | Flavonoids |
| Subclass | Flavones |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Flavonols |
| Alternative Parents | 4'-O-methylated flavonoids 3-hydroxyflavonoids 5-hydroxyflavonoids 7-hydroxyflavonoids Chromones Phenoxy compounds Methoxybenzenes Anisoles 1-hydroxy-2-unsubstituted benzenoids Pyranones and derivatives 1-hydroxy-4-unsubstituted benzenoids Alkyl aryl ethers Vinylogous acids Heteroaromatic compounds Oxacyclic compounds Polyols Organic oxides Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | 3-hydroxyflavone - 4p-methoxyflavonoid-skeleton - Hydroxyflavonoid - 3-hydroxyflavonoid - 5-hydroxyflavonoid - 7-hydroxyflavonoid - Chromone - 1-benzopyran - Benzopyran - Anisole - Phenoxy compound - Phenol ether - Methoxybenzene - 1-hydroxy-2-unsubstituted benzenoid - 1-hydroxy-4-unsubstituted benzenoid - Pyranone - Alkyl aryl ether - Monocyclic benzene moiety - Benzenoid - Pyran - Vinylogous acid - Heteroaromatic compound - Ether - Organoheterocyclic compound - Oxacycle - Polyol - Organic oxide - Organic oxygen compound - Hydrocarbon derivative - Organooxygen compound - Aromatic heteropolycyclic compound |
| Descripción | This compound belongs to the class of organic compounds known as flavonols. These are compounds that contain a flavone (2-phenyl-1-benzopyran-4-one) backbone carrying a hydroxyl group at the 3-position. |
| External Descriptors | Flavones and Flavonols |
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| Sensibilidad | light & air & moisture sensitive |
|---|---|
| Peso molecular | 300.260 g/mol |
| XLogP3 | 2.200 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 2 |
| Exact Mass | 300.063 Da |
| Monoisotopic Mass | 300.063 Da |
| Topological Polar Surface Area | 96.200 Ų |
| Heavy Atom Count | 22 |
| Formal Charge | 0 |
| Complexity | 465.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Shaoyan Zhang, Jinfeng Ning, Qingqing Wang, Wei Wang. (2023) Fluorescence enhancement of flavonoids and its application in ingredient determination for some traditional Chinese medicines by CE-LIF. Analytical Methods, 15 (24): (2964-2970). [PMID:37309583] [10.1039/D3AY00486D] |
| 2. Jie Zhao, Lin Huang, Renjie Li, Zhuangwei Zhang, Jin Chen, Hongjin Tang. (2022) Insights from multi-spectroscopic analysis and molecular modeling to understand the structure–affinity relationship and the interaction mechanism of flavonoids with gliadin. Food & Function, 13 (9): (5061-5074). [PMID:35404372] [10.1039/D1FO03816H] |
| 3. Hongjin Tang, Lin Huang, Dongsheng Zhao, Chunyong Sun, Ping Song. (2020) Interaction mechanism of flavonoids on bovine serum albumin: Insights from molecular property-binding affinity relationship. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, [PMID:32480277] [10.1016/j.saa.2020.118519] |
| 4. Jie Zhao, Lin Huang, Chunyong Sun, Dongsheng Zhao, Hongjin Tang. (2020) Studies on the structure-activity relationship and interaction mechanism of flavonoids and xanthine oxidase through enzyme kinetics, spectroscopy methods and molecular simulations. FOOD CHEMISTRY, [PMID:32330646] [10.1016/j.foodchem.2020.126807] |
| 5. Rongxia Liu, Chaonan Su, Yumeng Xu, Kangle Shang, Kang Sun, Caihong Li, Jing Lu. (2020) Identifying potential active components of walnut leaf that action diabetes mellitus through integration of UHPLC-Q-Orbitrap HRMS and network pharmacology analysis. JOURNAL OF ETHNOPHARMACOLOGY, [PMID:32058009] [10.1016/j.jep.2020.112659] |
| 6. Yu-Mei Zhao, Lv-Huan Wang, Si-Fan Luo, Qi-Qin Wang, Ruin Moaddel, Ting-Ting Zhang, Zheng-Jin Jiang. (2018) Magnetic beads-based neuraminidase enzyme microreactor as a drug discovery tool for screening inhibitors from compound libraries and fishing ligands from natural products. JOURNAL OF CHROMATOGRAPHY A, [PMID:30005943] [10.1016/j.chroma.2018.07.031] |
| 7. Jing-Yi Hao, Yi Wan, Xiao-Hui Yao, Wei-Guo Zhao, Run-Ze Hu, Cong Chen, Long Li, Dong-Yang Zhang, Guo-Hua Wu. (2018) Effect of different planting areas on the chemical compositions and hypoglycemic and antioxidant activities of mulberry leaf extracts in Southern China. PLoS One, 13 (6): (e0198072). [PMID:29944667] [10.1371/journal.pone.0198072] |
| 8. Lite Yang, Bingjie Xu, Huili Ye, Faqiong Zhao, Baizhao Zeng. (2017) A novel quercetin electrochemical sensor based on molecularly imprinted poly(para-aminobenzoic acid) on 3D Pd nanoparticles-porous graphene-carbon nanotubes composite. SENSORS AND ACTUATORS B-CHEMICAL, [PMID:] [10.1016/j.snb.2017.04.006] |
| 9. Yang Huang, Ying Feng, Guangyun Tang, Minyi Li, Tingting Zhang, Marianne Fillet, Jacques Crommen, Zhengjin Jiang. (2017) Development and validation of a fast SFC method for the analysis of flavonoids in plant extracts. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, [PMID:28347593] [10.1016/j.jpba.2017.03.012] |
| 10. Shuzhen Yang, Jie Zhou, Dongmei Li, Chunyu Shang, Litao Peng, Siyi Pan. (2016) The structure-antifungal activity relationship of 5,7-dihydroxyflavonoids against Penicillium italicum. FOOD CHEMISTRY, [PMID:28159264] [10.1016/j.foodchem.2016.12.001] |
| 11. Qi Yun, Qingwang Liu, Cunyong He, Xiaohua Ma, Xiaoli Gao, Amer Talbi, Jianping Zhou. (2014) UPLC-Q-TOF/MS characterization, HPLC fingerprint analysis and species differentiation for quality control of Nigella glandulifera Freyn et Sint seeds and Nigella sativa L. seeds. Analytical Methods, 6 (13): (4845-4852). [PMID:] [10.1039/C4AY00775A] |
| 12. Hui Cao, Xiaohui Jing, Donghui Wu, Yujun Shi. (2013) Methylation of genistein and kaempferol improves their affinities for proteins. INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION, [PMID:23311465] [10.3109/09637486.2012.759186] |
| 13. Qingqing Wang, Junlan Ye, Wei Wang. (2025) Study of Bacteriostasis of Kaempferide on Foodborne Pathogenic Bacteria by Indirect Determination of Capillary Electrophoresis. ELECTROPHORESIS, [PMID:40916637] [10.1002/elps.70023] |
| 14. Anyi Wu, Junping Zhou, Yinan Xue, Yun Liu, Jidong Shen, Xin Gao, Zhiqiang Liu, Yuguo Zheng. (2025) Efficient multi-enzyme system for icaritin production from naringenin with synchronous prenol utilization in Escherichia coli. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, [PMID:41314575] [10.1016/j.ijbiomac.2025.149283] |
| 15. Changhai Sun, Mengxin Xiao, Biyue Cui, Shiyuan Sun, Shushuang Shen, Shuting Zhang, Xinran Zhang, Liting Mu. (2026) Study on the Correlation Between Anthoxanthins Compounds' Reverse-Phase Chromatographic Behavior and Their Solubility. JOURNAL OF MOLECULAR STRUCTURE, [PMID:] [10.1016/j.molstruc.2026.145944] |
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