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KDM5-C49 hydrochloride - ≥99% , CAS No.K658789
Disponible para pedir
GRADE & PURITY ≥99%
Storage
Store at 2-8°C,Desiccated
Shipped In
Wet ice
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Why this grade
≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Storage & shipping
Store at 2-8°C,Desiccated Ships Wet ice Check lot-specific COA for exact specifications.
Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Descripción general
KDM5-C49 (KDOAM-20) hydrochloride is a potent and selective inhibitor of KDM5 demethylases , with IC 50 s of 40 nM, 160 nM, and 100 nM for KDM5A , KDM5B , and KDM5C enzymes , respectively. KDM5-C49 hydrochloride can be used for the research of cancer
Appearance:Solid-liquid mixture
In Vitro:KDM5-C49 hydrochloride display poor permeability. Convert the carboxylate group of KDM5-C49 into an ethyl ester, to get a cell-permeable prodrug (KDM5-C70). MCE has not independently confirmed the accuracy of these methods. They are for reference onl
Biological Activity:KDM5-C49 (KDOAM-20) hydrochloride is a potent and selective inhibitor of KDM5 demethylases , with IC 50 s of 40 nM, 160 nM, and 100 nM for KDM5A , KDM5B , and KDM5C enzymes , respectively. KDM5-C49 hydrochloride can be used for the research of cancer
Specifications
Especificaciones y pureza
≥99%
Condiciones de almacenamiento de almacenamiento
Store at 2-8°C, Desiccated
Enviado en
Wet ice
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Tipo de acción
INHIBITOR
Pureza
≥99%
Nombres e identificadores
| Peso molecular | 344.84 |
|---|
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →✅ Certificate of Analysis (COA)
Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →🔬 Specification Sheet
Full quality attributes and acceptance criteria for this grade.
View spec sheet →Advanced Data
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propiedades químicas y físicas
| Solubilidad | DMSO : 125 mg/mL (362.49 mM; Need ultrasonic) |
|---|
Calculadoras de soluciones
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