Ketotifen Fumarate - 10mM in DMSO , Histamine H1 receptor antagonist, CAS No.34580-14-8, Histamine H1 receptor antagonist

CAS: 34580-14-8 Cat. No.: K408699 Peso molecular: 425.5 Número EC: 252-100-0
Disponible para pedir
GRADE & PURITY 10mM in DMSO
Synonyms
4,​9-​dihydro-​4-​(1-​methyl-​4-​piperidinylidene)​-10H-​benzo[4,​5]​cyclohepta[1,​2-​b]​thiophen-​10-​one,(2E)​-​2-​butenedioate (1:1)
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
1ml
K408699-1ml
1

114,90US$

166,90US$
Guardar 52,00 US$ (31.16%)
Enter a quantity for the sizes you want to add.
🧪

Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 1 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Information

Ketotifen Fumarate is a fumaric acid salt of ketotifen which is a H1-antihistamine and mast cell stabilizer.
In vitro


In vivo


Cell Data

cell lines:

Concentrations:

Incubation Time:

Powder Purity:≥99%

Specifications

Sinónimos
4, ​9-​dihydro-​4-​(1-​methyl-​4-​piperidinylidene)​-10H-​benzo[4, ​5]​cyclohepta[1, ​2-​b]​thiophen-​10-​one, (2E)​-​2-​butenedioate (1:1)
Especificaciones y pureza
10mM in DMSO
Mecanismos bioquímicos y fisiológicos
Ketotifen Fumarate is a fumaric acid salt of ketotifen which is a H1-antihistamine and mast cell stabilizer.
Condiciones de almacenamiento de almacenamiento
Store at -80°C
Enviado en
Dry ice packs + Cold packs
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Tipo de acción
ANTAGONIST
Mecanismo de acción
Histamine H1 receptor antagonist
Nombres e identificadores
Isómeros SMILES CN1CCC(=C2C3=C(C(=O)CC4=CC=CC=C42)SC=C3)CC1.C(=C/C(=O)O)\C(=O)O
WGK Alemania 3
RTECS DE8260000
Peso molecular 425.5
Reaxy-Rn 40483148
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=40483148&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Objetivos asociados (humanos)
HRH1 Tclin Histamine H1 receptor (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propiedades químicas y físicas
SolubilidadSolubility (25°C) In vitro      
Punto de fusión (°C)192°C
Citations of This Product
Referencias
1. Mingkang Zhang, Jinru Yang, Yufan Yuan, Yan Zhou, Yazhi Wang, Ruirui Cui, Yimai Maliu, Fen Xu, Xin’an Wu.  (2024)  Recruitment or activation of mast cells in the liver aggravates the accumulation of fibrosis in carbon tetrachloride-induced liver injury.  MOLECULAR IMMUNOLOGY,      [PMID:38626622] [10.1016/j.molimm.2024.04.009]
Calculadoras de soluciones
Reseñas

Reseñas de cliente

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.