KN-93 Phosphate - ≥99% , CAS No.1188890-41-6

CAS: 1188890-41-6 Cat. No.: K274961 Peso molecular: 599.03

GRADE & PURITY ≥99%

Synonyms

1188890-41-6 | s7423 | KN 93 phosphate | KN-93 phosphate (water soluble) | F20700 | HB0360 | EX-A2086 | N-[2-[[[3-(4-Chlorophenyl)-2-propenyl]methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxybenzenesulphonamide phosphate | AC-33085 | (E)-N-(2-(((3-(

Storage

Protected from light,Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

Descripción general

Store at -20°C. It is important to note that this product is reported to be light sensitive. Store In the Dark. Store under desiccating conditions.

Specifications

Sinónimos

1188890-41-6 | s7423 | KN 93 phosphate | KN-93 phosphate (water soluble) | F20700 | HB0360 | EX-A2086 | N-[2-[[[3-(4-Chlorophenyl)-2-propenyl]methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxybenzenesulphonamide phosphate | AC-33085 | (E)-N-(2-(((3-(

Especificaciones y pureza

≥99%

Mecanismos bioquímicos y fisiológicos

Potent, specific and cell-permeable calmodulin-dependent protein kinase (CaMK) II inhibitor (IC 50 = 370 nM). Also a potent and direct extracellular open channel voltage-gated potassium channel blocker (IC 50 = 307 nM for Kv1.5).

Condiciones de almacenamiento de almacenamiento

Protected from light, Store at -20°C, Desiccated

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Tipo de acción

INHIBITOR

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureza

≥99%

Nombres e identificadores

• Pubchem Sid: 504768534
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504768534
• Sonrisas canónicas: CN(CC=CC1=CC=C(C=C1)Cl)CC2=CC=CC=C2N(CCO)S(=O)(=O)C3=CC=C(C=C3)OC.OP(=O)(O)O
• IUPAC Name: N-[2-[[[(E)-3-(4-chlorophenyl)prop-2-enyl]-methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide;phosphoric acid
• InChIKey: NNKJTPOXLIILMB-IPZCTEOASA-N
• INCHI: 1S/C26H29ClN2O4S.H3O4P/c1-28(17-5-6-21-9-11-23(27)12-10-21)20-22-7-3-4-8-26(22)29(18-19-30)34(31,32)25-15-13-24(33-2)14-16-25;1-5(2,3)4/h3-16,30H,17-20H2,1-2H3;(H3,1,2,3,4)/b6-5+
• Isómeros SMILES: CN(C/C=C/C1=CC=C(C=C1)Cl)CC2=CC=CC=C2N(CCO)S(=O)(=O)C3=CC=C(C=C3)OC.OP(=O)(O)O
• Peso molecular: 599.03
• Reaxy-Rn: 18467446
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=18467446&ln=

Propiedades químicas y físicas

• Solubilidad: Soluble in water to 100 mM and in DMSO to 100 mM
• Sensibilidad: light sensitive
• Peso molecular: 599.000 g/mol
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 11
• Exact Mass: 598.131 Da
• Monoisotopic Mass: 598.131 Da
• Topological Polar Surface Area: 156.000 Ų
• Heavy Atom Count: 39
• Formal Charge: 0
• Complexity: 763.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 1
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 1
• Covalently-Bonded Unit Count: 2

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