L-Norvaline - ≥99% , CAS No.6600-40-4

CAS: 6600-40-4 Cat. No.: N106215 Peso molecular: 117.15 Beilstein Registry Number: 1721162 Número EC: 229-543-3

GRADE & PURITY ≥99%

Synonyms

Pentanoic acid, 2-amino-, (S)- | Q418707 | C01826 | DB04185 | A70UKS48FE | L-2-aminopentanoate | BDBM50357215 | Valeric acid, 2-amino- | AM20100599 | EINECS 229-543-3 | Norvaline (VAN) | HY-Y0399 | MFCD00064421 | SNDPXSYFESPGGJ-BYPYZUCNSA-N | (2S)-2-amino

Storage

Room temperature

Shipped In

Normal

Descripción general

L-Norvaline enhances NO production from activated macrophages. arginase inhibitor

Application

L-Norvaline enhances NO production from activated macrophages. It is known to promote tissue regeneration and muscle growth and become a precursor in the penicillin biosynthetic pathway. It also can be used for nutrition agent and drug synthesis. For example: it can react with phthalic acid anhydride to get N,N-phthaloyl-L-norvaline.

Specifications

Sinónimos

Pentanoic acid, 2-amino-, (S)- | Q418707 | C01826 | DB04185 | A70UKS48FE | L-2-aminopentanoate | BDBM50357215 | Valeric acid, 2-amino- | AM20100599 | EINECS 229-543-3 | Norvaline (VAN) | HY-Y0399 | MFCD00064421 | SNDPXSYFESPGGJ-BYPYZUCNSA-N | (2S)-2-amino

Especificaciones y pureza

≥99%

Mecanismos bioquímicos y fisiológicos

L-Norvaline enhances NO production from activated macrophages.

Condiciones de almacenamiento de almacenamiento

Room temperature

Enviado en

Normal

Tipo de acción

ANTAGONIST

Pureza

≥99%

Nombres e identificadores

• Pubchem Sid: 488183665
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488183665
• Sonrisas canónicas: CCCC(C(=O)O)N
• IUPAC Name: (2S)-2-aminopentanoic acid
• InChIKey: SNDPXSYFESPGGJ-BYPYZUCNSA-N
• INCHI: 1S/C5H11NO2/c1-2-3-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m0/s1
• Isómeros SMILES: CCC[C@@H](C(=O)O)N
• WGK Alemania: 3
• Peso molecular: 117.15
• Beilstein: 1721162
• Reaxy-Rn: 1721160
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1721160&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Clase Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Alpha amino acids and derivatives
            • Level7 Alpha amino acids
              • Level8 L-alpha-amino acids

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Clase: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives - Alpha amino acids and derivatives - Alpha amino acids
• Direct Parent: L-alpha-amino acids
• Alternative Parents: Methyl-branched fatty acids Amino acids Monocarboxylic acids and derivatives Carboxylic acids Organopnictogen compounds Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: L-alpha-amino acid - Branched fatty acid - Methyl-branched fatty acid - Fatty acid - Fatty acyl - Amino acid - Monocarboxylic acid or derivatives - Carboxylic acid - Organic oxide - Organopnictogen compound - Organic oxygen compound - Primary amine - Organooxygen compound - Organonitrogen compound - Primary aliphatic amine - Carbonyl group - Organic nitrogen compound - Amine - Hydrocarbon derivative - Aliphatic acyclic compound
• Descripción: This compound belongs to the class of organic compounds known as l-alpha-amino acids. These are alpha amino acids which have the L-configuration of the alpha-carbon atom.
• External Descriptors: Amino fatty acids

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Objetivos asociados (humanos)

SLC36A1 Tchem Proton-coupled amino acid transporter 1 (102 Activities)

Discover Target: SLC36A1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de acción

Propiedades químicas y físicas

• Solubilidad: Soluble in water (almost transparency), 10.5 g/100 mL (18°C).
• Rotación específica [α]: +23.0 to +26.0 deg(C=10, 6mol/L HCl)
• Punto de fusión (°C): ＞300°C
• Peso molecular: 117.150 g/mol
• XLogP3: -2.100
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 117.079 Da
• Monoisotopic Mass: 117.079 Da
• Topological Polar Surface Area: 63.300 Ų
• Heavy Atom Count: 8
• Formal Charge: 0
• Complexity: 82.500
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 1
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Referencias

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