L-Ornithine monohydrochloride - ≥98% , CAS No.3184-13-2

CAS: 3184-13-2 Cat. No.: O108803 Peso molecular: 168.62 Beilstein Registry Number: 4420 Número EC: 221-678-6

GRADE & PURITY ≥98%

Synonyms

L(+)-Ornithine hydrochloride | (S)-2,5-Diaminopentanoic acid monohydrochloride | H-Orn-OH.HCl | L-Ornithine hydrochloride | Ornithine monohydrochloride | L-ORNITHINE HCl | (S)-2,5-Diaminopentanoic acid hydrochloride | L-Ornithine, monohydrochloride

Storage

Room temperature

Shipped In

Normal

Descripción general

L-Ornithine hydrochloride is a non-proteinogenic amino acid, is mainly used in urea cycle removing excess nitrogen in vivo. L-Ornithine hydrochloride shows nephroprotective.

Specifications

Sinónimos

L(+)-Ornithine hydrochloride | (S)-2, 5-Diaminopentanoic acid monohydrochloride | H-Orn-OH.HCl | L-Ornithine hydrochloride | Ornithine monohydrochloride | L-ORNITHINE HCl | (S)-2, 5-Diaminopentanoic acid hydrochloride | L-Ornithine, monohydrochloride

Especificaciones y pureza

≥98%

Mecanismos bioquímicos y fisiológicos

L-Ornithine is a product of arginase degradation and plays an important role in ammonia metabolism via the urea cycle. In mammals, ornithine serves as a precursor for polyamines and proline biosynthesis. Spermine synthesized from ornithine, is an abundant

Condiciones de almacenamiento de almacenamiento

Room temperature

Enviado en

Normal

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureza

≥98%

Nombres e identificadores

• Sonrisas canónicas: Cl.NCCC[C@H](N)C(O)=O
• IUPAC Name: (2S)-2,5-diaminopentanoic acid;hydrochloride
• InChIKey: GGTYBZJRPHEQDG-WCCKRBBISA-N
• INCHI: 1S/C5H12N2O2.ClH/c6-3-1-2-4(7)5(8)9;/h4H,1-3,6-7H2,(H,8,9);1H/t4-;/m0./s1
• Isómeros SMILES: C(C[C@@H](C(=O)O)N)CN.Cl
• RTECS: RM2985000
• CAS alternativo: 70-26-8
• Peso molecular: 168.62
• Beilstein: 4420
• Reaxy-Rn: 4328590
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=4328590&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Clase Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Alpha amino acids and derivatives
            • Level7 Alpha amino acids
              • Level8 L-alpha-amino acids

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Clase: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives - Alpha amino acids and derivatives - Alpha amino acids
• Direct Parent: L-alpha-amino acids
• Alternative Parents: Fatty acids and conjugates Amino acids Monocarboxylic acids and derivatives Carboxylic acids Organopnictogen compounds Organic oxides Monoalkylamines Hydrochlorides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: L-alpha-amino acid - Fatty acid - Amino acid - Monocarboxylic acid or derivatives - Carboxylic acid - Organic oxide - Hydrocarbon derivative - Organic oxygen compound - Hydrochloride - Organic nitrogen compound - Primary amine - Organooxygen compound - Organonitrogen compound - Primary aliphatic amine - Carbonyl group - Amine - Organopnictogen compound - Aliphatic acyclic compound
• Descripción: This compound belongs to the class of organic compounds known as l-alpha-amino acids. These are alpha amino acids which have the L-configuration of the alpha-carbon atom.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Mecanismos de acción

Propiedades químicas y físicas

• Solubilidad: Solubility in water: 543 G/L WATER (20° C),Solubility in other solvents: soluble in mineral acids insoluble in most common organic solvents
• Sensibilidad: Hygroscopic
• Índice de refracción: 1.52
• Rotación específica [α]: +22.0 to +25.0 deg(C=4, 6mol/L HCl)
• Punto de ebullición (°C): 308.7 °C
• Punto de fusión (°C): 245℃
• Peso molecular: 168.620 g/mol
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 168.067 Da
• Monoisotopic Mass: 168.067 Da
• Topological Polar Surface Area: 89.300 Ų
• Heavy Atom Count: 10
• Formal Charge: 0
• Complexity: 95.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 1
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3

Referencias

1. Zhou Kai, Zhang Xiao, Li Bingyong, Shen Chaoqun, Sun Yuan-Ming, Yang Jianyuan, Xu Zhen-Lin.  (2021)  Citrulline Accumulation Mechanism of Pediococcus acidilactici and Weissella confusa in Soy Sauce and the Effects of Phenolic Compound on Citrulline Accumulation.  Frontiers in Microbiology,      [PMID:34925267] [10.3389/fmicb.2021.757542]

2. Yuling Li, Bowen Zhou, Keke Wang, Jing Zhang, Wenjian Sun, Li Zhang, Yinlong Guo.  (2021)  Powerful Steroid-Based Chiral Selector for High-Throughput Enantiomeric Separation of α-Amino Acids Utilizing Ion Mobility–Mass Spectrometry.  ANALYTICAL CHEMISTRY,      [PMID:34597017] [10.1021/acs.analchem.1c02691]

3. Chengyi Xie, Liancheng Gu, Qidi Wu, Lei Li, Chenlu Wang, Jiancheng Yu, Keqi Tang.  (2020)  Effective Chiral Discrimination of Amino Acids through Oligosaccharide Incorporation by Trapped Ion Mobility Spectrometry.  ANALYTICAL CHEMISTRY,      [PMID:33226780] [10.1021/acs.analchem.0c03461]

4. Lili Zhang, Wen Duan, Yan Huang, Yuyu Zhang, Baoguo Sun, Dandan Pu, Yizhuang Tang, Chao Liu.  (2020)  Sensory taste properties of chicken (Hy-Line brown) soup as prepared with five different parts of the chicken.  INTERNATIONAL JOURNAL OF FOOD PROPERTIES,      [PMID:] [10.1080/10942912.2020.1828455]

5. Bi Guoshu, Liang Jiaqi, Bian Yunyi, Shan Guangyao, Huang Yiwei, Lu Tao, Zhang Huan, Jin Xing, Chen Zhencong, Zhao Mengnan, Fan Hong, Wang Qun, Gan Boyi, Zhan Cheng.  (2024)  Polyamine-mediated ferroptosis amplification acts as a targetable vulnerability in cancer.  Nature Communications,  15  (1): (1-20).  [PMID:38504107] [10.1038/s41467-024-46776-w]

6. Yifan Zhang, Youwei Zhu, Na Zhao, Jinhui Wu, Yiqiao Hu.  (2015)  Application of isothermal titration calorimeter for screening bitterness-suppressing molecules of quinine.  FOOD CHEMISTRY,      [PMID:26213068] [10.1016/j.foodchem.2015.06.070]