Lactobionic acid - ≥97% , CAS No.96-82-2

CAS: 96-82-2 Cat. No.: L109639 Peso molecular: 358.3 Beilstein Registry Number: 95054 Número EC: 202-538-3

GRADE & PURITY ≥97%

Synonyms

(2R,3R,4R,5R)-2,3,5,6-tetrahydroxy-4-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-hexanoic acid | AKOS015924795 | 4-(beta-D-Galactosido)-D-gluconic acid | D70310 | D-Gluconic acid, 4-O-.beta.-D-galactopyranosyl- | 2,3,5,6-t

Storage

Room temperature

Shipped In

Normal

Descripción general

Lactobionic acid is an inhibitor of MMP.
An inhibitor of matrix metalloproteinases

Specifications

Sinónimos

(2R, 3R, 4R, 5R)-2, 3, 5, 6-tetrahydroxy-4-[(2S, 3R, 4S, 5R, 6R)-3, 4, 5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxy-hexanoic acid | AKOS015924795 | 4-(beta-D-Galactosido)-D-gluconic acid | D70310 | D-Gluconic acid, 4-O-.beta.-D-galactopyranosyl- | 2, 3, 5, 6-t

Especificaciones y pureza

≥97%

Condiciones de almacenamiento de almacenamiento

Room temperature

Enviado en

Normal

Pureza

≥97%

Nombres e identificadores

• Pubchem Sid: 504751299
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504751299
• Sonrisas canónicas: C(C1C(C(C(C(O1)OC(C(CO)O)C(C(C(=O)O)O)O)O)O)O)O
• IUPAC Name: (2R,3R,4R,5R)-2,3,5,6-tetrahydroxy-4-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexanoic acid
• InChIKey: JYTUSYBCFIZPBE-AMTLMPIISA-N
• INCHI: 1S/C12H22O12/c13-1-3(15)10(7(18)8(19)11(21)22)24-12-9(20)6(17)5(16)4(2-14)23-12/h3-10,12-20H,1-2H2,(H,21,22)/t3-,4-,5+,6+,7-,8-,9-,10-,12+/m1/s1
• Isómeros SMILES: C([C@@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)O[C@H]([C@@H](CO)O)[C@@H]([C@H](C(=O)O)O)O)O)O)O)O
• WGK Alemania: 1
• Número ONU: 3265
• Peso molecular: 358.3
• Beilstein: 95054
• Reaxy-Rn: 25712943
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=25712943&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Lipids and lipid-like molecules
    • Clase Fatty Acyls
      • Subclass Fatty acyl glycosides

• Kingdom: Organic compounds
• Superclass: Lipids and lipid-like molecules
• Clase: Fatty Acyls
• Subclass: Fatty acyl glycosides
• Intermediate Tree Nodes: Not available
• Direct Parent: Fatty acyl glycosides of mono- and disaccharides
• Alternative Parents: Disaccharides O-glycosyl compounds Medium-chain hydroxy acids and derivatives Medium-chain fatty acids Beta hydroxy acids and derivatives Sugar acids and derivatives Heterocyclic fatty acids Hydroxy fatty acids Alpha hydroxy acids and derivatives Oxanes Secondary alcohols Monocarboxylic acids and derivatives Carboxylic acids Oxacyclic compounds Polyols Acetals Hydrocarbon derivatives Primary alcohols Organic oxides Carbonyl compounds
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: Fatty acyl glycoside of mono- or disaccharide - Gluconic_acid - Disaccharide - Glycosyl compound - O-glycosyl compound - Medium-chain hydroxy acid - Medium-chain fatty acid - Beta-hydroxy acid - Heterocyclic fatty acid - Hydroxy fatty acid - Alpha-hydroxy acid - Fatty acid - Hydroxy acid - Oxane - Secondary alcohol - Acetal - Carboxylic acid derivative - Carboxylic acid - Oxacycle - Organoheterocyclic compound - Polyol - Monocarboxylic acid or derivatives - Hydrocarbon derivative - Organic oxygen compound - Organic oxide - Primary alcohol - Carbonyl group - Organooxygen compound - Alcohol - Aliphatic heteromonocyclic compound
• Descripción: This compound belongs to the class of organic compounds known as fatty acyl glycosides of mono- and disaccharides. These are compounds composed of a mono- or disaccharide moiety linked to one hydroxyl group of a fatty alcohol or of a phosphorylated alcohol (phosphoprenols), a hydroxy fatty acid or to one carboxyl group of a fatty acid (ester linkage) or to an amino alcohol.
• External Descriptors: disaccharide

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Objetivos asociados (no humanos)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de acción

Propiedades químicas y físicas

• Solubilidad: Soluble in water (50 mg/ml), glacial acetic acid (slightly), anhydrous ethanol (slightly), and methanol (slightly).
• Rotación específica [α]: 26 ° (C=8.8, H2O)
• Punto de fusión (°C): 113-118°C
• Peso molecular: 358.300 g/mol
• XLogP3: -5.000
• Hydrogen Bond Donor Count: 9
• Hydrogen Bond Acceptor Count: 12
• Rotatable Bond Count: 8
• Exact Mass: 358.111 Da
• Monoisotopic Mass: 358.111 Da
• Topological Polar Surface Area: 218.000 Ų
• Heavy Atom Count: 24
• Formal Charge: 0
• Complexity: 405.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 9
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Referencias

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2. Zi Chao Wu, Xin Yu Liu, Jia Yan Liu, Jing Shu Piao, Ming Guan Piao.  (2022)  Preparation of Betulinic Acid Galactosylated Chitosan Nanoparticles and Their Effect on Liver Fibrosis.  International Journal of Nanomedicine,      [PMID:36134203] [10.2147/IJN.S373430]

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22. Xin Yu Liu, He Ying Mao, Shuai Hong, Cheng-Hua Jin, Hu-Lin Jiang, Ming Guan Piao.  (2024)  Dual-targeting galactose-functionalized hyaluronic acid modified lipid nanoparticles delivering silybin for alleviating alcoholic liver injury.  INTERNATIONAL JOURNAL OF PHARMACEUTICS,      [PMID:39241932] [10.1016/j.ijpharm.2024.124662]

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