Lauroyl-L-carnitine - ≥94%(HPLC) , CAS No.25518-54-1

CAS: 25518-54-1 Cat. No.: L463319 Peso molecular: 343.5 Beilstein Registry Number: 4147610

GRADE & PURITY ≥94%(HPLC)

Synonyms

C12 Carnitine, lauroyl L-carnitine, powder | CHEBI:77086 | O-dodecanoyl-L-carnitine | W05IWQ0V44 | Lauroyl-L-carnitine, >=97.0% (TLC) | AKOS037646352 | Scandium Std - Sc @ 500 microg/g in 75 cSt Oil | SCHEMBL1958560 | HY-113166 | (3R)-3-(dodecanoyloxy)-4

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Descripción general

Dodecanoylcarnitine is present in fatty acid oxidation disorders such as long-chain acyl CoA dehydrogenase deficiency, carnitine palmitoyltransferase I/II deficiency, and is also associated with celiac disease.

Application：

Lauroyl-L-carnitine finds application in biochemical research and metabolomics research.

Specifications

Sinónimos

C12 Carnitine, lauroyl L-carnitine, powder | CHEBI:77086 | O-dodecanoyl-L-carnitine | W05IWQ0V44 | Lauroyl-L-carnitine, >=97.0% (TLC) | AKOS037646352 | Scandium Std - Sc @ 500 microg/g in 75 cSt Oil | SCHEMBL1958560 | HY-113166 | (3R)-3-(dodecanoyloxy)-4

Especificaciones y pureza

≥94%(HPLC)

Mecanismos bioquímicos y fisiológicos

Lauroyl-L-carnitine is an acylcarnitine is present in fatty acid oxidation disorders such as long-chain acyl CoA dehydrogenase deficiency, carnitine palmitoyltransferase I deficiency, and carnitine palmitoyltransferase II deficiency.

Condiciones de almacenamiento de almacenamiento

Store at -20°C

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Pureza

≥94%(HPLC)

Nombres e identificadores

• Sonrisas canónicas: CCCCCCCCCCCC(=O)OC(CC(=O)[O-])C[N+](C)(C)C
• IUPAC Name: (3R)-3-dodecanoyloxy-4-(trimethylazaniumyl)butanoate
• InChIKey: FUJLYHJROOYKRA-QGZVFWFLSA-N
• INCHI: 1S/C19H37NO4/c1-5-6-7-8-9-10-11-12-13-14-19(23)24-17(15-18(21)22)16-20(2,3)4/h17H,5-16H2,1-4H3/t17-/m1/s1
• Isómeros SMILES: CCCCCCCCCCCC(=O)O[C@H](CC(=O)[O-])C[N+](C)(C)C
• Peso molecular: 343.5
• Beilstein: 4147610
• Reaxy-Rn: 4147608
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=4147608&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Lipids and lipid-like molecules
    • Clase Fatty Acyls
      • Subclass Fatty acid esters

• Kingdom: Organic compounds
• Superclass: Lipids and lipid-like molecules
• Clase: Fatty Acyls
• Subclass: Fatty acid esters
• Intermediate Tree Nodes: Not available
• Direct Parent: Acyl carnitines
• Alternative Parents: Dicarboxylic acids and derivatives Tetraalkylammonium salts Carboxylic acid salts Carboxylic acid esters Carboxylic acids Organopnictogen compounds Organic salts Organic oxides Hydrocarbon derivatives Carbonyl compounds Amines
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Acyl-carnitine - Dicarboxylic acid or derivatives - Tetraalkylammonium salt - Quaternary ammonium salt - Carboxylic acid ester - Carboxylic acid salt - Carboxylic acid derivative - Carboxylic acid - Organic nitrogen compound - Organooxygen compound - Organonitrogen compound - Organic salt - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic oxygen compound - Carbonyl group - Amine - Aliphatic acyclic compound
• Descripción: This compound belongs to the class of organic compounds known as acyl carnitines. These are organic compounds containing a fatty acid with the carboxylic acid attached to carnitine through an ester bond.
• External Descriptors: O-acyl-L-carnitine - O-dodecanoylcarnitine - laurate ester

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Solubilidad: Methanol:50 mg/mL (145.56 mM),Need ultrasonic
• Rotación específica [α]: [α]/D -20±2°, c = 1 in methanol
• Punto de inflamación (°F): Not applicable
• Punto de inflamación (°C): Not applicable
• Peso molecular: 343.500 g/mol
• XLogP3: 5.500
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 15
• Exact Mass: 343.272 Da
• Monoisotopic Mass: 343.272 Da
• Topological Polar Surface Area: 66.400 Ų
• Heavy Atom Count: 24
• Formal Charge: 0
• Complexity: 344.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 1
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Referencias

1. Jie Zhang, Xiaoling Zang, Peng Jiao, Jiangyu Wu, Wei Meng, Lizhen Zhao, Zhihua Lv.  (2024)  Alterations of Ceramides, Acylcarnitines, GlyceroLPLs, and Amines in NSCLC Tissues.  JOURNAL OF PROTEOME RESEARCH,      [PMID:39317643] [10.1021/acs.jproteome.4c00344]