10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Desiccated,Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Descripción general
LCL521 dihydrochloride is an acid ceramidase ( ACDase ) inhibitor. LCL521 also inhibits the lysosomal acid sphingomyelinase ( ASMase )
In Vitro
LCL521 (1 µM) acts as a potent inhibitor of cellular ACDase activity, whereas 10 µM LCL521 has an additional, decreased affect on the α-form of this enzyme. LCL521 (10µM) causes a time-dependent (1 hours and 5 hours) decrease of the α-ACDase form in MCF7 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
IC50& Target:ACDase, ASMase
Specifications
Especificaciones y pureza
10mM in DMSO
Mecanismos bioquímicos y fisiológicos
LCL521 dihydrochloride is an acid ceramidase ( ACDase ) inhibitor. LCL521 also inhibits the lysosomal acid sphingomyelinase ( ASMase ).
Condiciones de almacenamiento de almacenamiento
Desiccated, Store at -80°C
Enviado en
Dry ice packs + Cold packs
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
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