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· · COA & SDS Disponible para cada producto · Same-day shipping on in-stock items LDN 212854 - ≥98%(HPLC) , CAS No.1432597-26-6
Synonyms
SB19484 | BDBM102618 | CCG-268725 | LDN 212854 | C72696 | BCP08633 | 5-(6-(4-(1-Piperazinyl)phenyl)pyrazolo[1,5-a]pyrimidin-3-yl)quinoline | AS-16555 | BMP Inhibitor III | AKOS026750252 | EX-A425 | LDN 212854;LDN212854 | LDN212854 | LDN-212854 | NCGC00386
Shipped In
Ice chest + Ice pads
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Why this grade ≥98%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Sinónimos
SB19484 | BDBM102618 | CCG-268725 | LDN 212854 | C72696 | BCP08633 | 5-(6-(4-(1-Piperazinyl)phenyl)pyrazolo[1, 5-a]pyrimidin-3-yl)quinoline | AS-16555 | BMP Inhibitor III | AKOS026750252 | EX-A425 | LDN 212854;LDN212854 | LDN212854 | LDN-212854 | NCGC00386
Especificaciones y pureza
≥98%(HPLC)
Mecanismos bioquímicos y fisiológicos
Potent ALK inhibitor (IC50values are 1.3, 2.4, 85.8, 2, 133 and 9, 276 nM for ALK2, ALK1, ALK3, ALK4 and ALK5, respectively). Exhibits selectivity for ALK2 over ALK4 and ALK5 in cellular assays. Inhibits heterotopic ossification in a mutant ALK2 mouse model
Condiciones de almacenamiento de almacenamiento
Store at -20°C
Enviado en
Ice chest + Ice pads
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Nombres e identificadores Pubchem Sid 504771798 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504771798 Sonrisas canónicas C1CN(CCN1)C2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=C6C=CC=NC6=CC=C5)N=C3 IUPAC Name 5-[6-(4-piperazin-1-ylphenyl)pyrazolo[1,5-a]pyrimidin-3-yl]quinoline InChIKey BBDGBGOVJPEFBT-UHFFFAOYSA-N INCHI 1S/C25H22N6/c1-3-21(22-4-2-10-27-24(22)5-1)23-16-29-31-17-19(15-28-25(23)31)18-6-8-20(9-7-18)30-13-11-26-12-14-30/h1-10,15-17,26H,11-14H2 Isómeros SMILES C1CN(CCN1)C2=CC=C(C=C2)C3=CN4C(=C(C=N4)C5=C6C=CC=NC6=CC=C5)N=C3 Peso molecular 406.48 Reaxy-Rn 23637228 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=23637228&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Clase Diazines Subclass Pyrimidines and pyrimidine derivatives Intermediate Tree Nodes Not available Direct Parent Phenylpyrimidines Alternative Parents Phenylpiperazines N-arylpiperazines Quinolines and derivatives Pyrazolo[1,5-a]pyrimidines Dialkylarylamines Aniline and substituted anilines Pyridines and derivatives Pyrazoles Heteroaromatic compounds Dialkylamines Azacyclic compounds Hydrocarbon derivatives Molecular Framework Aromatic heteropolycyclic compounds Substituents Phenylpiperazine - 5-phenylpyrimidine - N-arylpiperazine - Quinoline - Pyrazolo[1,5-a]pyrimidine - Pyrazolopyrimidine - Tertiary aliphatic/aromatic amine - Aniline or substituted anilines - Dialkylarylamine - Benzenoid - Monocyclic benzene moiety - Pyridine - Piperazine - 1,4-diazinane - Azole - Heteroaromatic compound - Pyrazole - Tertiary amine - Secondary amine - Azacycle - Secondary aliphatic amine - Amine - Hydrocarbon derivative - Organonitrogen compound - Organic nitrogen compound - Aromatic heteropolycyclic compound Descripción This compound belongs to the class of organic compounds known as phenylpyrimidines. These are polycyclic aromatic compounds containing a benzene ring linked to a pyrimidine ring through a CC or CN bond. Pyrimidine is a 6-membered ring consisting of four carbon atoms and two nitrogen centers at the 1- and 3- ring positions. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Estructura 3D Objetivos asociados (humanos) Objetivos asociados (no humanos) Mecanismos de acción Certificados (CoA, COO, BSE/TSE y tabla de análisis) Propiedades químicas y físicas Solubilidad Solvent:2eq.HCl, Max Conc. mg/mL: 20.32, Max Conc. mM: 50 Peso molecular 406.500 g/mol XLogP3 3.300 Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 5 Rotatable Bond Count 3 Exact Mass 406.191 Da Monoisotopic Mass 406.191 Da Topological Polar Surface Area 58.400 Ų Heavy Atom Count 31 Formal Charge 0 Complexity 587.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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