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· · COA & SDS Disponible para cada producto · Same-day shipping on in-stock items LE 135 - Moligand™, ≥97%(HPLC) , CAS No.155877-83-1
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%(HPLC) Synonyms
4-(5,7,7,10,10-Pentamethyl-7,8,9,10-tetrahydro-5H-benzo[e]naphtho[2,3-b][1,4]diazepin-13-yl)benzoic acid | LE135 | LE-135 | BRD-K06593056-001-01-4 | CHEBI:92124 | DTXSID70439469 | SCHEMBL1132584 | J-009253 | MS-27866 | ST 24:1;O2;T | BDBM50061616 | 4-(5,7
Shipped In
Ice chest + Ice pads
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Why this grade Moligand™, ≥97%(HPLC) Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Descripción general Application：
LE 135 has been used for in vitro islet treatment.
Specifications Sinónimos
4-(5, 7, 7, 10, 10-Pentamethyl-7, 8, 9, 10-tetrahydro-5H-benzo[e]naphtho[2, 3-b][1, 4]diazepin-13-yl)benzoic acid | LE135 | LE-135 | BRD-K06593056-001-01-4 | CHEBI:92124 | DTXSID70439469 | SCHEMBL1132584 | J-009253 | MS-27866 | ST 24:1;O2;T | BDBM50061616 | 4-(5, 7
Especificaciones y pureza
Moligand™, ≥97%(HPLC)
Mecanismos bioquímicos y fisiológicos
Retinoic acid antagonist; displays moderate selectivity for RARβover RARα(Kivalues are 0.22 and 1.4μM respectively). Highly selective over RARγand RXRα. Inhibits human HL-60 leukemia cell differentiation induced by Am80 (IC50= 150 nM).LE135 is a retinoic
Condiciones de almacenamiento de almacenamiento
Store at -20°C
Enviado en
Ice chest + Ice pads
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Nombres e identificadores Pubchem Sid 488196651 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/488196651 Sonrisas canónicas CC1(CCC(C2=CC3=C(C=C21)N=C(C4=CC=CC=C4N3C)C5=CC=C(C=C5)C(=O)O)(C)C)C IUPAC Name 4-(5,7,7,10,10-pentamethyl-8,9-dihydronaphtho[2,3-b][1,4]benzodiazepin-13-yl)benzoic acid InChIKey YZZAIQOVMHVWBS-UHFFFAOYSA-N INCHI 1S/C29H30N2O2/c1-28(2)14-15-29(3,4)22-17-25-23(16-21(22)28)30-26(18-10-12-19(13-11-18)27(32)33)20-8-6-7-9-24(20)31(25)5/h6-13,16-17H,14-15H2,1-5H3,(H,32,33) Isómeros SMILES CC1(CCC(C2=CC3=C(C=C21)N=C(C4=CC=CC=C4N3C)C5=CC=C(C=C5)C(=O)O)(C)C)C WGK Alemania 3 Peso molecular 438.56 Reaxy-Rn 6943175 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=6943175&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organoheterocyclic compounds Clase Benzodiazepines Subclass Dibenzodiazepines Intermediate Tree Nodes Not available Direct Parent Dibenzodiazepines Alternative Parents Alkyldiarylamines 1,4-benzodiazepines Tetralins Benzoic acids Benzoyl derivatives Ketimines Amino acids Propargyl-type 1,3-dipolar organic compounds Monocarboxylic acids and derivatives Carboxylic acids Azacyclic compounds Organopnictogen compounds Organooxygen compounds Organic oxides Hydrocarbon derivatives Molecular Framework Aromatic heteropolycyclic compounds Substituents Dibenzodiazepine - Alkyldiarylamine - 1,4-benzodiazepine - Tetralin - Benzoic acid or derivatives - Benzoic acid - Benzoyl - Tertiary aliphatic/aromatic amine - Monocyclic benzene moiety - Benzenoid - Amino acid - Ketimine - Amino acid or derivatives - Tertiary amine - Monocarboxylic acid or derivatives - Carboxylic acid - Carboxylic acid derivative - Azacycle - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Organooxygen compound - Organonitrogen compound - Hydrocarbon derivative - Imine - Organopnictogen compound - Amine - Organic oxygen compound - Organic nitrogen compound - Organic oxide - Aromatic heteropolycyclic compound Descripción This compound belongs to the class of organic compounds known as dibenzodiazepines. These are compounds containing a dibenzodiazepine moiety, which consists of two benzene connected by diazepine ring. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Estructura 3D Objetivos asociados (humanos) Objetivos asociados (no humanos) Mecanismos de acción Certificados (CoA, COO, BSE/TSE y tabla de análisis) Propiedades químicas y físicas Solubilidad Solvent:DMSO, Max Conc. mg/mL: 43.86, Max Conc. mM: 100 Peso molecular 438.600 g/mol XLogP3 7.400 Hydrogen Bond Donor Count 1 Hydrogen Bond Acceptor Count 4 Rotatable Bond Count 2 Exact Mass 438.231 Da Monoisotopic Mass 438.231 Da Topological Polar Surface Area 52.900 Ų Heavy Atom Count 33 Formal Charge 0 Complexity 778.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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View Moligand™ grade guide →
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