≥95% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Information
Lesinurad sodium Lesinurad (Selexipag, RDEA-594) sodium (Zurampic) is a selective uric acid reabsorption inhibitor (SURI) under investigation for treatment of gout. Lesinurad sodium inhibits the uric acid transporter URAT1 and Kidney transporter OAT with IC50/Km of 4.3 μM/0.85 μM and 3.5 μM/2 μM for OAT1 and OAT3, respectively.
Targets
URAT1 ; OAT1 (Cell-free assay); OAT3 (Cell-free assay); OAT3 (Cell-free assay); OAT1 (Cell-free assay) ; 0.85 μM(Km); 2 μM(Km); 3.5 μM; 4.3 μM
| ALogP | 2.783 |
|---|---|
| hba_count | 2 |
| Enlace rotable | 5 |
| Pubchem Sid | 488201789 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488201789 |
| Sonrisas canónicas | C1CC1C2=CC=C(C3=CC=CC=C23)N4C(=NN=C4Br)SCC(=O)[O-].[Na+] |
| IUPAC Name | sodium;2-[[5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-1,2,4-triazol-3-yl]sulfanyl]acetate |
| InChIKey | FVYMVLTWIBGEMC-UHFFFAOYSA-M |
| INCHI | 1S/C17H14BrN3O2S.Na/c18-16-19-20-17(24-9-15(22)23)21(16)14-8-7-11(10-5-6-10)12-3-1-2-4-13(12)14;/h1-4,7-8,10H,5-6,9H2,(H,22,23);/q;+1/p-1 |
| Isómeros SMILES | C1CC1C2=CC=C(C3=CC=CC=C23)N4C(=NN=C4Br)SCC(=O)[O-].[Na+] |
| Peso molecular | 426.26 |
| Reaxy-Rn | 19298555 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=19298555&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Clase | Azoles |
| Subclass | Triazoles |
| Intermediate Tree Nodes | Phenyltriazoles |
| Direct Parent | Phenyl-1,2,4-triazoles |
| Alternative Parents | Naphthalenes Alkylarylthioethers Aryl bromides Heteroaromatic compounds Carboxylic acid salts Sulfenyl compounds Azacyclic compounds Carboxylic acids Monocarboxylic acids and derivatives Organic metal halides Organic zwitterions Organonitrogen compounds Hydrocarbon derivatives Carbonyl compounds Organic sodium salts Organobromides Organic oxides |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Phenyl-1,2,4-triazole - Naphthalene - Aryl thioether - Alkylarylthioether - Aryl bromide - Aryl halide - Benzenoid - Heteroaromatic compound - Carboxylic acid salt - Carboxylic acid derivative - Organic metal halide - Carboxylic acid - Monocarboxylic acid or derivatives - Thioether - Sulfenyl compound - Azacycle - Organic alkali metal salt - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Organobromide - Organohalogen compound - Organic oxide - Organic nitrogen compound - Hydrocarbon derivative - Organic zwitterion - Organic oxygen compound - Carbonyl group - Organic salt - Organic sodium salt - Aromatic heteropolycyclic compound |
| Descripción | This compound belongs to the class of organic compounds known as phenyl-1,2,4-triazoles. These are organic compounds containing a 1,2,4-triazole substituted by a phenyl group. |
| External Descriptors | Not available |
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Fecha | Articulo |
|---|---|---|---|
 G2304568 | Certificate of Analysis | Apr 03, 2026 | L413240 |
| G2304570 | Certificate of Analysis | Apr 03, 2026 | L413240 |
| G2304571 | Certificate of Analysis | Apr 03, 2026 | L413240 |
| G2304574 | Certificate of Analysis | Apr 03, 2026 | L413240 |
| G2304575 | Certificate of Analysis | Apr 03, 2026 | L413240 |
| G2304609 | Certificate of Analysis | Apr 03, 2026 | L413240 |
| G2304694 | Certificate of Analysis | Apr 03, 2026 | L413240 |
| G2304695 | Certificate of Analysis | Apr 03, 2026 | L413240 |
| G2304696 | Certificate of Analysis | Apr 03, 2026 | L413240 |
| G2304572 | Certificate of Analysis | May 26, 2023 | L413240 |
| Solubilidad | Solubility (25°C) In vitro DMSO: 85 mg/mL (199.4 mM); Ethanol: 85 mg/mL (199.4 mM); Water: 8 mg/mL (18.76 mM); |
|---|---|
| DMSO (mg/ml) Solubilidad máxima | 85 |
| DMSO (mM) Solubilidad máxima | 199.408811523483 |
| Agua (mg/ml) Solubilidad máxima | 8 |
| Agua (mM) Solubilidad máxima | 18.7678881433867 |
| Peso molecular | 426.300 g/mol |
| XLogP3 | |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 5 |
| Exact Mass | 424.981 Da |
| Monoisotopic Mass | 424.981 Da |
| Topological Polar Surface Area | 96.100 Ų |
| Heavy Atom Count | 25 |
| Formal Charge | 0 |
| Complexity | 485.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 2 |
