Leu-Gly-Gly - ≥98% , CAS No.1187-50-4

CAS: 1187-50-4 Cat. No.: L121359 Peso molecular: 245.28 Beilstein Registry Number: 1728928 Número EC: 214-698-1

GRADE & PURITY ≥98%

Synonyms

(S)-2-(2-(2-Amino-4-methylpentanamido)acetamido)acetic acid | HY-W012003 | L-Leu-Gly-Gly | Q27144715 | [2-((S)-2-Amino-4-methyl-pentanoylamino)-acetylamino]-acetic acid | CHEBI:74538 | l-leucylglycylglycine | L-Leucyl-glycyl-glycine | 0962ABF0-21F5-4144-B

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Specifications

Sinónimos

(S)-2-(2-(2-Amino-4-methylpentanamido)acetamido)acetic acid | HY-W012003 | L-Leu-Gly-Gly | Q27144715 | [2-((S)-2-Amino-4-methyl-pentanoylamino)-acetylamino]-acetic acid | CHEBI:74538 | l-leucylglycylglycine | L-Leucyl-glycyl-glycine | 0962ABF0-21F5-4144-B

Especificaciones y pureza

≥98%

Mecanismos bioquímicos y fisiológicos

Leucylglycylglycine (DL-Leu-Gly-Gly) may be used to study the effects of branched-chain di- and tripeptides on cell envelope-associated proteinases (CEPs) activity. L-Leu-Gly-Gly may be used as a substrate to study the kinetics of tripeptide aminopeptidas

Condiciones de almacenamiento de almacenamiento

Store at -20°C

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Pureza

≥98%

Nombres e identificadores

• Pubchem Sid: 504754586
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504754586
• Sonrisas canónicas: CC(C)CC(C(=O)NCC(=O)NCC(=O)O)N
• IUPAC Name: 2-[[2-[[(2S)-2-amino-4-methylpentanoyl]amino]acetyl]amino]acetic acid
• InChIKey: VWHGTYCRDRBSFI-ZETCQYMHSA-N
• INCHI: 1S/C10H19N3O4/c1-6(2)3-7(11)10(17)13-4-8(14)12-5-9(15)16/h6-7H,3-5,11H2,1-2H3,(H,12,14)(H,13,17)(H,15,16)/t7-/m0/s1
• Isómeros SMILES: CC(C)C[C@@H](C(=O)NCC(=O)NCC(=O)O)N
• WGK Alemania: 3
• Peso molecular: 245.28
• Beilstein: 1728928
• Reaxy-Rn: 1728926
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1728926&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Clase Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Clase: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Not available
• Direct Parent: Peptides
• Alternative Parents: N-acyl-alpha amino acids Amino acids Propargyl-type 1,3-dipolar organic compounds Monocarboxylic acids and derivatives Carboxylic acids Carboximidic acids Organopnictogen compounds Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Alpha peptide - N-acyl-alpha-amino acid - N-acyl-alpha amino acid or derivatives - Alpha-amino acid or derivatives - Amino acid or derivatives - Amino acid - Carboximidic acid - Carboximidic acid derivative - Carboxylic acid - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Monocarboxylic acid or derivatives - Organic nitrogen compound - Organonitrogen compound - Organooxygen compound - Primary amine - Primary aliphatic amine - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Carbonyl group - Organic oxygen compound - Amine - Aliphatic acyclic compound
• Descripción: This compound belongs to the class of organic compounds known as peptides. These are compounds containing an amide derived from two or more amino carboxylic acid molecules (the same or different) by formation of a covalent bond from the carbonyl carbon of one to the nitrogen atom of another.
• External Descriptors: tripeptide

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Objetivos asociados (humanos)

SLC15A1 Tchem Oligopeptide transporter small intestine isoform (922 Activities)

Discover Target: SLC15A1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SLC15A2 Tchem Solute carrier family 15 member 2 (186 Activities)

Discover Target: SLC15A2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de acción

Propiedades químicas y físicas

• Peso molecular: 245.280 g/mol
• XLogP3: -3.000
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 7
• Exact Mass: 245.138 Da
• Monoisotopic Mass: 245.138 Da
• Topological Polar Surface Area: 122.000 Ų
• Heavy Atom Count: 17
• Formal Charge: 0
• Complexity: 291.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 1
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Referencias

1. Zhixian Wu, Xueyong Zheng, Chunli Jiang, Junhan Xie, Weimin Liu, Bo Li, Hechun Lin, Hui Peng, Chunhua Luo.  (2025)  Peptide-Engineered Interface to Improve the Efficiency of Pure Red Tin Halide Perovskite LEDs by Controlling Crystallization and Reducing Oxidation.  ACS Applied Electronic Materials,      [PMID:] [10.1021/acsaelm.4c01935]