Determine the necessary mass, volume, or concentration for preparing a solution.
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≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Room temperature Ships Normal Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 22 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
| Pubchem Sid | 488183066 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488183066 |
| Sonrisas canónicas | C1CSC2=NC(CN21)C3=CC=CC=C3.Cl |
| IUPAC Name | (6S)-6-phenyl-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole;hydrochloride |
| InChIKey | LAZPBGZRMVRFKY-HNCPQSOCSA-N |
| INCHI | 1S/C11H12N2S.ClH/c1-2-4-9(5-3-1)10-8-13-6-7-14-11(13)12-10;/h1-5,10H,6-8H2;1H/t10-;/m1./s1 |
| Isómeros SMILES | C1CSC2=N[C@H](CN21)C3=CC=CC=C3.Cl |
| Número ONU | 2811 |
| Grupo de embalaje | III |
| Peso molecular | 240.75 |
| Reaxy-Rn | 4358987 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=4358987&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Clase | Imidazothiazoles |
| Subclass | Not available |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Imidazothiazoles |
| Alternative Parents | Benzene and substituted derivatives Thiazolidines Imidazolines Isothioureas Propargyl-type 1,3-dipolar organic compounds Carboximidamides Azacyclic compounds Organopnictogen compounds Hydrochlorides Hydrocarbon derivatives |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Imidazothiazole - Monocyclic benzene moiety - Benzenoid - 2-imidazoline - Thiazolidine - Isothiourea - Propargyl-type 1,3-dipolar organic compound - Carboximidamide - Azacycle - Organic 1,3-dipolar compound - Hydrochloride - Organonitrogen compound - Hydrocarbon derivative - Organopnictogen compound - Organic nitrogen compound - Aromatic heteropolycyclic compound |
| Descripción | This compound belongs to the class of organic compounds known as imidazothiazoles. These are organic polycyclic compounds containing an imidazole ring fused to a thiazole ring. Imidazole is 5-membered ring consisting of three carbon atoms, and two nitrogen centers at the 1- and 3-positions. Thiazole is a 6-membered ring that contains both sulfur and nitrogen. |
| External Descriptors | organic molecular entity |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Fecha | Articulo |
|---|---|---|---|
| Certificate of Analysis | Jun 15, 2026 | L118865 | |
| Certificate of Analysis | Jun 15, 2026 | L118865 | |
| Certificate of Analysis | Apr 13, 2026 | L118865 | |
| Certificate of Analysis | Apr 13, 2026 | L118865 | |
| Certificate of Analysis | Jul 08, 2025 | L118865 | |
| Certificate of Analysis | Jun 22, 2022 | L118865 | |
| Certificate of Analysis | Jun 22, 2022 | L118865 | |
| Certificate of Analysis | Jun 22, 2022 | L118865 | |
| Certificate of Analysis | Jun 22, 2022 | L118865 | |
| Certificate of Analysis | Jun 22, 2022 | L118865 | |
| Certificate of Analysis | Jun 22, 2022 | L118865 | |
| Certificate of Analysis | Jun 22, 2022 | L118865 | |
| Certificate of Analysis | Jun 22, 2022 | L118865 | |
| Certificate of Analysis | Jan 19, 2022 | L118865 |
| Solubilidad | Easily soluble in chloroform, insoluble in acetone |
|---|---|
| Rotación específica [α] | -126 ° (C=1, H2O) |
| Punto de fusión (°C) | 228-230°C |
| Peso molecular | 240.750 g/mol |
| XLogP3 | |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 1 |
| Exact Mass | 240.049 Da |
| Monoisotopic Mass | 240.049 Da |
| Topological Polar Surface Area | 40.900 Ų |
| Heavy Atom Count | 15 |
| Formal Charge | 0 |
| Complexity | 246.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 1 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 2 |
| 1. Shuna Chen, Jiaxin Kang, Huanqing Zhu, Ziyi Han, Leyu Wang, Kaixi Wang, Junsheng Liu, Yuanyuan Wu, Puming He, Youying Tu, Bo Li. (2023) Tea seed saponins ameliorate cyclophosphamide-induced intestinal injury, immune disorder and gut microbial dysbiosis in mice. Food Bioscience, [PMID:] [10.1016/j.fbio.2023.103504] |
| 2. Anqi Xie, Hao Wan, Lei Feng, Boyun Yang, Yiqun Wan. (2023) Protective Effect of Anoectochilus formosanus Polysaccharide against Cyclophosphamide-Induced Immunosuppression in BALB/c Mice. Foods, 12 (9): (1910). [PMID:37174447] [10.3390/foods12091910] |
| 3. Han Mengyao, Zhang Zhongshan, Li Xinyue, Tong Haibin, Xu Zhiguo, Ding Zikang, Yang Anquan, Xie Min, Wang Xiaomei. (2022) Effects of collagen peptides from Micropterus salmoides skin on oxidative damage induced by cyclophosphamide in mice. Frontiers in Nutrition, [PMID:36407538] [10.3389/fnut.2022.1037212] |
| 4. Chao Han, Ying Wang, Ruiying Liu, Beibei Ran, Weidong Li. (2022) Structural characterization and protective effect of Lonicerae flos polysaccharide on cyclophosphamide-induced immunosuppression in mice. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, [PMID:34999342] [10.1016/j.ecoenv.2022.113174] |
| 5. Pengshuai Zhang, Yameng Wan, Chi Zhang, Rui Zhao, Jiao Sha, Yu Li, Tao Li, Baozeng Ren. (2019) Solubility and mixing thermodynamic properties of levamisole hydrochloride in twelve pure solvents at various temperatures. JOURNAL OF CHEMICAL THERMODYNAMICS, [PMID:] [10.1016/j.jct.2019.105882] |
| 6. Huiting Fang, Huizhen Li, Yang Chen, Xiaoming Liu, Jianxin Zhao, Paul Ross, Catherine Stanton, Wei Chen, Bo Yang. (2024) Bifidobacterium breve CCFM1310 enhances immunity in immunosuppressed mice via modulating immune response and gut microbiota. Food Bioscience, [PMID:] [10.1016/j.fbio.2024.104058] |
| 7. Yahui Jia, Zhiqiang Zhang, Siming Zhang, Xia Ma, Yuan Ruan, Bingji Ma, Li Wang. (2024) Effects of polysaccharide from hot-compressed steamed Rehmannia glutinosa on the immune system and gut microbiota in an immunosuppressed mice model. INTERNATIONAL IMMUNOPHARMACOLOGY, [PMID:39303540] [10.1016/j.intimp.2024.113202] |
| 8. Ying Yang, Mengfan Luo, Wanyi Zhou, Wenyang Tao, Jingrui Li, Jianrong Xing, Quanqin Tan, Yuxing Guo. (2024) Lactiplantibacillus plantarum YY-112 ameliorates mouse immunosuppression by enhancing B/T-cell activation and maintaining Th1/Th2 homeostasis. Food Frontiers, [PMID:] [10.1002/fft2.477] |
| 9. Weiguang Luo, Xiuwei Li, Chenxi Zhang, Kai Shen, Mengxue Li, Yan Zhuang, Jinhai Huo, Weiming Wang. (2025) Physicochemical characterization and protective effects of raw and nine-steamed Polygonatum cyrtonema polysaccharides on cyclophosphamide-induced immunosuppression in mice. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, [PMID:40068755] [10.1016/j.ijbiomac.2025.141911] |
| 10. Lin Chen, Qihong Jiang, Shiwei Yao, Chenkai Jiang, Hongling Lu, Wenjun Hu, Shaofang Yu, Mingqian Li, Yongcai Feng, Chin Ping Tan, Xingwei Xiang, Guoxin Shen. (2024) Sciadonic acid ameliorates cyclophosphamide-induced immunosuppression by modulating the immune response and altering the gut microbiota. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, [PMID:38264943] [10.1002/jsfa.13271] |
| 11. Xinru Du, Yongheng Yan, Yufeng Dai, Ruijie Xu. (2024) Yogurt Alleviates Cyclophosphamide-Induced Immunosuppression in Mice through D-Lactate. Nutrients, 16 (9): (1395). [PMID:38732641] [10.3390/nu16091395] |
| 12. Mengling Zhong, Mingmei Feng, Xinlin Chen, Yuxin Zhang, Yupeng Wang, Peizhi Yuan, Tianyao Zhang, Zhipeng Han, Chenglun Tang, Qi Zhang, Yang Sun. (2025) Cordycepin attenuated cyclophosphamide (CTX)-induced immunosuppression in mice via EGFR/Nrf2 antioxidant signaling pathway. INTERNATIONAL IMMUNOPHARMACOLOGY, [PMID:40695148] [10.1016/j.intimp.2025.115235] |
| 13. Xian-Yi Jin, Jia Luo, Hang Cong, Jiang-Lin Zhao. (2025) Synergic Electrochemiluminescence System with Hemicucurbituril-Based CQDs and a Chiral Macrocycle for Recognition Toward Levamisole Hydrochloride. ChemistrySelect, 10 (28): (e00823). [PMID:] [10.1002/slct.202500823] |
| 14. Ming Zhao, Huiyan Huang, Bowen Li, Yu Pan, Chuankai Wang, Wanjia Du, Wenliang Wang, Yansheng Wang, Xue Mao, Xianghui Kong. (2025) Preparation of Auricularia auricula-Derived Immune Modulators and Alleviation of Cyclophosphamide-Induced Immune Suppression and Intestinal Microbiota Dysbiosis in Mice. Life-Basel, 15 (8): (1236). [PMID:40868884] [10.3390/life15081236] |
| 15. Pengshuai Zhang, Jiao Sha, Yameng Wan, Chi Zhang, Tao Li, Baozeng Ren. (2019) Apparent thermodynamic analysis and the dissolution behavior of levamisole hydrochloride in three binary solvent mixtures. THERMOCHIMICA ACTA, [PMID:] [10.1016/j.tca.2019.178375] |
| 16. Song Wang, Chenyu Jiang, Shitong Yu, Qianru Fan, Kai Yang, Jianqin Huang, Yan Li. (2025) Hickory nut polyphenols enhance oxidative stress resilience and improve the longevity of Caenorhabditis elegans through modulating DAF-16/DAF-2 insulin/IGF-1 signaling. PHYTOMEDICINE, [PMID:40466506] [10.1016/j.phymed.2025.156918] |
| 17. Aijing Jia, Yucong Xu, Chaonan Sun, Hongwei Luan, Zhiteng Liu, Ying Bu, Wenhui Zhu, Xuepeng Li. (2025) Identification and molecular mechanisms of novel antioxidant peptides from Manila clam hydrolysate: Caenorhabditis elegans model, molecular simulations, and quantum chemistry. FOOD CHEMISTRY, [PMID:40516351] [10.1016/j.foodchem.2025.145079] |
| 18. Li Wang, Yupeng Yang, Xuelian Tang, Chunnan Wen, Zhiqiang Zhang, Xia Ma, Bingji Ma. (2025) Effects of polysaccharides from Stropharia rugosoannulata on cyclophosphamide-induced immunosuppression and hepatic injury in mice. JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, [PMID:41195471] [10.1002/jsfa.70295] |
| 19. Ji Zhang, Xueting Guan, Jianmei Zhang, Weicheng Hu, Chuanling Si, Honggang Wang, Ting Shen. (2025) Polysaccharides from lotus root residue alleviate cyclophosphamide-induced immunosuppression in mice. INDUSTRIAL CROPS AND PRODUCTS, [PMID:] [10.1016/j.indcrop.2025.122303] |
| 20. Caihong Chen, Haiyan Wu, Guanchao Zheng, Limin Lu, Zhijun Tan. (2025) Enhanced Toxicity of Diol-Estered Diarrhetic Shellfish Toxins Across Trophic Levels: Evidence from Caenorhabditis elegans and Mytilus galloprovincialis. Marine Drugs, 23 (12): (459). [PMID:41440892] [10.3390/md23120459] |
| 21. Shiqiong Xiang, Yang Chen, Jiayue Xia, Guiju Sun. (2025) Purification, Structural Characterization, and Immunomodulatory Activities of a Glucan from Morchella sextelata. Foods, 15 (1): (105). [PMID:41517171] [10.3390/foods15010105] |
| 22. Bo Li, Lin Zhang, Ding-Tao Wu, Qin Yuan, Shengpeng Wang, Mao-Ling Tan, Mei-Lin Feng, Yi-Chen Hu, Liang Zou, Zi-Peng Wang, Ya-Nan Cao, Jing-Wei Huang. (2026) Potential structure-immunostimulatory activity relationship of Tartary buckwheat sprout pectic polysaccharides: Influences of molecular mass and esterification degree. FOOD RESEARCH INTERNATIONAL, [PMID:] [10.1016/j.foodres.2026.118949] |