Levofloxacin hydrochloride - ≥98% , CAS No.177325-13-2

CAS: 177325-13-2 Cat. No.: L305201 Peso molecular: 397.83 Número EC: 605-797-4
Disponible para pedir
GRADE & PURITY ≥98%
Synonyms
Weilisu | Levofloxacin (hydrochloride) | (S)-9-Fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylic acid hydrochloride | HTN0D03VRZ
Storage
Store at 2-8°C,Protected from light,Argon charged
Shipped In
Wet ice
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
5g
L305201-5g
2

16,90US$

25,90US$
Guardar 9,00 US$ (34.75%)
25g
L305201-25g
2

63,90US$

95,90US$
Guardar 32,00 US$ (33.37%)
100g
L305201-100g
1

202,90US$

304,90US$
Guardar 102,00 US$ (33.45%)
500g
L305201-500g
1

760,90US$

1.141,90US$
Guardar 381,00 US$ (33.37%)
Enter a quantity for the sizes you want to add.
🧪

Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at 2-8°C,Protected from light,Argon charged Ships Wet ice Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 13 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Levofloxacin Hydrochloride is a fluoroquinolone broad spectrum antibiotic. It is an inhibitor of two enzymes, DNA gyrase and topoisomerase IV.

Specifications

Sinónimos
Weilisu | Levofloxacin (hydrochloride) | (S)-9-Fluoro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-3, 7-dihydro-2H-[1, 4]oxazino[2, 3, 4-ij]quinoline-6-carboxylic acid hydrochloride | HTN0D03VRZ
Especificaciones y pureza
≥98%
Condiciones de almacenamiento de almacenamiento
Store at 2-8°C, Protected from light, Argon charged
Enviado en
Wet ice
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Pureza
≥98%
Nombres e identificadores
Pubchem Sid504765075
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504765075
Sonrisas canónicasCC1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)O.Cl
IUPAC Name(2S)-7-fluoro-2-methyl-6-(4-methylpiperazin-1-yl)-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylic acid;hydrochloride
InChIKeyCAOOISJXWZMLBN-PPHPATTJSA-N
INCHI1S/C18H20FN3O4.ClH/c1-10-9-26-17-14-11(16(23)12(18(24)25)8-22(10)14)7-13(19)15(17)21-5-3-20(2)4-6-21;/h7-8,10H,3-6,9H2,1-2H3,(H,24,25);1H/t10-;/m0./s1
Isómeros SMILES C[C@H]1COC2=C3N1C=C(C(=O)C3=CC(=C2N4CCN(CC4)C)F)C(=O)O.Cl
Peso molecular 397.83
Reaxy-Rn 8527394
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=8527394&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClaseQuinolines and derivatives
SubclassQuinoline carboxylic acids
Intermediate Tree Nodes Not available
Direct ParentQuinoline carboxylic acids
Alternative Parents Fluoroquinolones  N-arylpiperazines  Haloquinolines  Aminoquinolines and derivatives  Hydroquinolones  Benzoxazines  Hydroquinolines  Pyridinecarboxylic acids  Dialkylarylamines  Alkyl aryl ethers  N-methylpiperazines  Benzenoids  Aryl fluorides  Heteroaromatic compounds  Vinylogous amides  Trialkylamines  Amino acids  Oxacyclic compounds  Carboxylic acids  Azacyclic compounds  Hydrocarbon derivatives  Hydrochlorides  Organic oxides  Organofluorides  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents Quinoline-3-carboxylic acid - Fluoroquinolone - N-arylpiperazine - Aminoquinoline - Haloquinoline - Dihydroquinolone - Benzoxazine - Dihydroquinoline - Pyridine carboxylic acid - Pyridine carboxylic acid or derivatives - Dialkylarylamine - Tertiary aliphatic/aromatic amine - Alkyl aryl ether - N-methylpiperazine - N-alkylpiperazine - Aryl fluoride - Aryl halide - 1,4-diazinane - Piperazine - Pyridine - Benzenoid - Vinylogous amide - Heteroaromatic compound - Tertiary aliphatic amine - Tertiary amine - Amino acid or derivatives - Amino acid - Azacycle - Oxacycle - Carboxylic acid derivative - Carboxylic acid - Ether - Organic nitrogen compound - Hydrocarbon derivative - Organohalogen compound - Organofluoride - Organic oxide - Amine - Hydrochloride - Organonitrogen compound - Organooxygen compound - Organic oxygen compound - Aromatic heteropolycyclic compound
DescripciónThis compound belongs to the class of organic compounds known as quinoline carboxylic acids. These are quinolines in which the quinoline ring system is substituted by a carboxyl group at one or more positions.
External Descriptors Not available
Estructura 3D
Modelo de Estructura Química Interactiva





Objetivos asociados (humanos)
Homo sapiens (32628 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Objetivos asociados (no humanos)
Staphylococcus aureus (210822 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Bacillus subtilis (32866 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Aspergillus fumigatus (16427 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Candida albicans (78123 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

18 results found

Lot NumberCertificate TypeFechaArticulo
C2307241Certificate of AnalysisDec 12, 2025 L305201
H2507793Certificate of AnalysisJul 12, 2025 L305201
H2507792Certificate of AnalysisJul 12, 2025 L305201
H2507791Certificate of AnalysisJul 12, 2025 L305201
H2507597Certificate of AnalysisJul 12, 2025 L305201
G2509091Certificate of AnalysisAug 30, 2024 L305201
H2409552Certificate of AnalysisAug 30, 2024 L305201
H2409553Certificate of AnalysisAug 30, 2024 L305201
H2409554Certificate of AnalysisAug 30, 2024 L305201
H2409555Certificate of AnalysisAug 30, 2024 L305201
H2409556Certificate of AnalysisAug 30, 2024 L305201
L2315013Certificate of AnalysisMar 19, 2022 L305201
K2316060Certificate of AnalysisMar 19, 2022 L305201
F2204896Certificate of AnalysisMar 19, 2022 L305201
F2204895Certificate of AnalysisMar 19, 2022 L305201
F2204894Certificate of AnalysisMar 19, 2022 L305201
F2204893Certificate of AnalysisMar 19, 2022 L305201
C2418076Certificate of AnalysisMar 19, 2022 L305201

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Propiedades químicas y físicas
SolubilidadAqueous Base (Slightly), DMSO (Slightly, Heated), Methanol (Slightly)
SensibilidadAir sensitive;Moisture sensitive
Punto de inflamación (°C)299.4°C
Punto de ebullición (°C)571.5°C
Peso molecular397.800 g/mol
XLogP3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count8
Rotatable Bond Count2
Exact Mass397.12 Da
Monoisotopic Mass397.12 Da
Topological Polar Surface Area73.300 Ų
Heavy Atom Count27
Formal Charge0
Complexity634.000
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count2
Citations of This Product
Referencias
1. Xiaojing Qin, Rongrong Tao, Song Cheng, Baolin Xing, Weibo Meng, Yanhe Nie, Chuanxiang Zhang, Jianglong Yu.  (2023)  Microwave-assisted one-pot method preparation of ZnO decorated biochar for levofloxacin and Cr(Ⅵ) removal from wastewater.  INDUSTRIAL CROPS AND PRODUCTS,      [PMID:] [10.1016/j.indcrop.2023.117863]
2. Xiaoting Yu, Fengfan Zhu, Boyi Yang, Jiancheng Zhou, Ke Wang, Nan Wang, Naixu Li.  (2023)  Novel BiVO4/SiC/Cu2O ternary composite photocatalyst coupled with carbonized wood for simultaneous water evaporation and purification driven by solar energy.  SEPARATION AND PURIFICATION TECHNOLOGY,      [PMID:] [10.1016/j.seppur.2023.124307]
3. Bing Liu, Xia Zhang, Jialong Chu, Fei Li, Caixia Jin, Jing Fan.  (2023)  2D/2D BiOIO3/Ti3C2 MXene nanocomposite with efficient charge separation for degradation of multiple pollutants.  APPLIED SURFACE SCIENCE,      [PMID:] [10.1016/j.apsusc.2023.156565]
4. Lu Min, Liu Bingxin, Xiong Wenbin, Liu Xinchun.  (2022)  The Combination of Salmonella Phage ST-3 and Antibiotics to Prevent Salmonella Typhimurium In Vitro.  CURRENT MICROBIOLOGY,  79  (12): (1-10).  [PMID:36269452] [10.1007/s00284-022-03073-3]
5. Yanzhuo Zhang, Jing Zhao.  (2022)  Comparison of different S-doped biochar materials to activate peroxymonosulfate for efficient degradation of antibiotics.  CHEMOSPHERE,      [PMID:36126742] [10.1016/j.chemosphere.2022.136442]
6. Xin-Yuan Jiang, Zong-Yi Ren, Nian-Kun Zhang, Ke-Chen Yang, Gao-Xue Wang, Hai-Feng Jiang.  (2022)  Screening and evaluating honokiol from Magnolia officinalis against Nocardia seriolae infection in largemouth bass (Micropterus Salmoides).  JOURNAL OF FISH DISEASES,  45  (11): (1599-1607).  [PMID:35801398] [10.1111/jfd.13683]
7. Yuan Qu, Heng Qian, Yiduo Mi, Jingjing He, Haixiang Gao, Runhua Lu, Sanbing Zhang, Wenfeng Zhou.  (2020)  Rapid determination of the pesticide ametryn based on a colorimetric aptasensor of gold nanoparticles.  Analytical Methods,  12  (14): (1919-1925).  [PMID:] [10.1039/D0AY00283F]
8. Xiang Li, Lijuan Liang, Wei Xu, Shuangjiao Li, Shengbo Yuan, Haijuan Zhan, Wanyi Liu.  (2025)  Constructing a robust built-in electric field via adjusting the charge distribution from surface-to-bulk of phosphorus and benzene ring co-doped C3N5 for enhanced photocatalytic performance.  JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY,      [PMID:] [10.1016/j.jmst.2024.12.098]
9. Mengyue Wang, Yu Wang, Nanjiong Pang, Mingyao Wang, Yunxiang He, Xiaoling Wang, Junling Guo.  (2024)  Efficient Removal of Tetracyclines and Quinolones Enabled by Polyphenol-Mediated Supramolecular Coagulation.  LANGMUIR,      [PMID:38320295] [10.1021/acs.langmuir.3c03261]
10. Rui Fang, Ning Yu, Fa Wang, Xi Xu, Jianfa Zhang.  (2025)  Hemoadhican Fiber Composite with Carbon Dots for Treating Severe Hemorrhage and Infected Wounds.  ACS Applied Materials & Interfaces,      [PMID:39882714] [10.1021/acsami.4c20176]
11. Wuxia Ge, Yumei Chen, Xinru Ding, Wentao Bi, David Da Yong Chen.  (2025)  Green synthesis of magnetic aromatic polyamide composites via mechanochemical ball milling with a deep eutectic system for the magnetic solid-phase extraction of antibiotics from water.  JOURNAL OF CHROMATOGRAPHY A,      [PMID:40043643] [10.1016/j.chroma.2025.465830]
12. Jingjing Wang, Waqas Ahmad, Yuzhen Liang, Yi Xu, Tianhui Jiao, Peipei Qi, Xingyu Lin, Quansheng Chen.  (2025)  Electrochemical synthesis of ultra-compact gold hexagonal nanostar substrate for enhanced and stable SERS detection.  ANALYTICA CHIMICA ACTA,      [PMID:41285526] [10.1016/j.aca.2025.344779]
13. Kaixin Sun, Bo Gong, Chang Xu, Shan Zhao, Shuguang Wang, Le Ren, Chao Song.  (2025)  Enhancing the degradation of ciprofloxacin and levofloxacin by peroxydisulfate (PDS): Multiple roles of co-existing copper ion.  Journal of Environmental Chemical Engineering,  13  (6): (120491).  [PMID:] [10.1016/j.jece.2025.120491]
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