Proteína quinasa activada por mitógenos 1 (MAP3K1)

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  1. GSK461364, Serine/threonine-protein kinase PLK1 inhibitor
    CAS: 929095-18-1 Formula: C27H28F3N5O2S Peso molecular: 543.62
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
    En Stock Articulo #: G127124
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    Identificadores técnicos
    Nombre IUPAC
    5-[6-[(4-methylpiperazin-1-yl)methyl]benzimidazol-1-yl]-3-[(1R)-1-[2-(trifluoromethyl)phenyl]ethoxy]thiophene-2-carboxamide
    SMILES
    CC(C1=CC=CC=C1C(F)(F)F)OC2=C(SC(=C2)N3C=NC4=C3C=C(C=C4)CN5CCN(CC5)C)C(=O)N
    InChIKey
    ZHJGWYRLJUCMRT-QGZVFWFLSA-N
    InChI
    1S/C27H28F3N5O2S/c1-17(19-5-3-4-6-20(19)27(28,29)30)37-23-14-24(38-25(23)26(31)36)35-16-32-21-8-7-18(13-22(21)35)15-34-11-9-33(2)10-12-34/h3-8,13-14,1show more
    Sinónimos
    CCG-264940 | GTPL5684 | SW220052-1 | AC-23167 | GSK 461364 | 5-[6-[(4-Methyl-1-piperazinyl)methyl]-1h-benzimidazol-1-...
  2. GSK461364, Serine/threonine-protein kinase PLK1 inhibitor
    CAS: 929095-18-1 Formula: C27H28F3N5O2S Peso molecular: 543.62
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    En Stock Articulo #: G408291
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    Identificadores técnicos
    Sinónimos
    GSK461364A | 5-(6-((4-methylpiperazin-1-yl)methyl)-1H-benzo[d]imidazol-1-yl)-3-((R)-1-(2-(trifluoromethyl)phenyl)etho...
  3. X-376, Inhibitor of ALK receptor tyrosine kinase;Inhibitor of MET proto-oncogene; receptor tyrosine kinase
    CAS: 1365267-27-1 PubChem CID: 56960447 Formula: C25H25Cl2FN6O3 Peso molecular: 547.41
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
    En Stock Articulo #: X413489
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    Identificadores técnicos
    Nombre IUPAC
    6-amino-5-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-N-[4-(4-methylpiperazine-1-carbonyl)phenyl]pyridazine-3-carboxamide
    SMILES
    CC(C1=C(C=CC(=C1Cl)F)Cl)OC2=CC(=NN=C2N)C(=O)NC3=CC=C(C=C3)C(=O)N4CCN(CC4)C
    InChIKey
    ONPGOSVDVDPBCY-CQSZACIVSA-N
    InChI
    1S/C25H25Cl2FN6O3/c1-14(21-17(26)7-8-18(28)22(21)27)37-20-13-19(31-32-23(20)29)24(35)30-16-5-3-15(4-6-16)25(36)34-11-9-33(2)10-12-34/h3-8,13-14H,9-12Hshow more
    Sinónimos
    7DR7JMB8BH | NSC800968 | NSC-800968 | s6505 | X-396 | MS-30029 | X-376; X-396 | DB13104 | AKOS030528612 | BDBM5043289...
  4. X-376, Inhibitor of ALK receptor tyrosine kinase;Inhibitor of MET proto-oncogene; receptor tyrosine kinase
    CAS: 1365267-27-1 PubChem CID: 56960447 Formula: C25H25Cl2FN6O3 Peso molecular: 547.41
    Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
    En Stock Articulo #: X421388
    Vista del artículo
    Precios y tamaños del paquete
    Identificadores técnicos
    Nombre IUPAC
    6-amino-5-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-N-[4-(4-methylpiperazine-1-carbonyl)phenyl]pyridazine-3-carboxamide
    SMILES
    CC(C1=C(C=CC(=C1Cl)F)Cl)OC2=CC(=NN=C2N)C(=O)NC3=CC=C(C=C3)C(=O)N4CCN(CC4)C
    InChIKey
    ONPGOSVDVDPBCY-CQSZACIVSA-N
    InChI
    1S/C25H25Cl2FN6O3/c1-14(21-17(26)7-8-18(28)22(21)27)37-20-13-19(31-32-23(20)29)24(35)30-16-5-3-15(4-6-16)25(36)34-11-9-33(2)10-12-34/h3-8,13-14H,9-12Hshow more
    Sinónimos
    7DR7JMB8BH | NSC800968 | NSC-800968 | s6505 | X-396 | MS-30029 | X-376; X-396 | DB13104 | AKOS030528612 | BDBM5043289...
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