Datopotamab deruxtecan (anti-TROP2) - Primary antibody, specific to TACSTD2, >90% (SDS-PAGE&SEC), Human IgG1

CAS: 2238831-60-0 Cat. No.: Ab183314
Disponible para pedir
GRADE & PURITY Animal Free ? Animal-free — produced without animal-derived components to reduce contamination risk. Use in biomanufacturing and culture avoiding animal-origin material. Carrier Free ? Carrier-free — supplied without added carrier protein/stabilizer. Use when carriers (e.g. BSA) would interfere with conjugation or sensitive assays. Recombinant ? Recombinant — produced via recombinant expression for defined sequence and consistency. Use for reproducible, animal-free proteins of known origin. Validated ? Validated grade — performance confirmed in defined applications before release. Use when you want documented assurance the reagent works as stated. ExactAb™ ? ExactAb™ — Aladdin's antibody line emphasizing precision and validated quality. Use for reliable, specificity-validated antibody applications. Low Endotoxin ? Low-endotoxin grade — endotoxin reduced to low controlled levels. Use in sensitive biological work where high endotoxin would interfere. Azide Free ? Azide-free — without sodium azide preservative. Use in conjugations, cell work, or assays where azide is toxic or inhibitory. ≥90%(SDS-PAGE&SEC-HPLC) See COA
Application
Animal Model, ELISA, Flow Cytometry, Functional Assay
Host species
Human
Reactive species
Cynomolgus monkey, Human, Rat
Isotype
Human IgG1
Conjugation
MC-GGFG-DXd
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
100μg
Ab183314-100μg
10
301,90US$
1mg
Ab183314-1mg
2
1.509,90US$
5mg
Ab183314-5mg
1
3.775,90US$
10mg
Ab183314-10mg
1-2 wks(?)
Item is derived from our semi-finished stock and is processed in 1-2 weeks.
6.041,90US$
Enter a quantity for the sizes you want to add.
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Why this grade

Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥90%(SDS-PAGE&SEC-HPLC), See COA Animal Free,Azide Free,Carrier Free,ExactAb™,Low Endotoxin,Recombinant,Validated for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C,Avoid repeated freezing and thawing Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Datopotamab deruxtecan (anti-TROP2) is a trophoblast cell surface antigen 2 (TROP2)-directed antibody-drug conjugate (ADC). Datopotamab deruxtecan (anti-TROP2) has a potent antitumor activity.
Purity
>90% (SDS-PAGE&SEC)
Endotoxin Level
< 1.0EU/mg

Specifications

Product Name
Datopotamab deruxtecan (anti-TROP2) - Primary antibody, specific to TACSTD2, >90% (SDS-PAGE&SEC), Human IgG1
Sinónimos
Cell surface glycoprotein Trop 2 antibody | Cell surface glycoprotein Trop-2 antibody | Cell surface glycoprotein Trop2 antibody | Epithelial glycoprotein 1 antibody | GA733 1 antibody | GA7331 antibody | M1S 1 antibody | M1S1 antibody | Membrane componen
Especificaciones y pureza
Carrier Free, Recombinant, ExactAb™, Low Endotoxin, Azide Free, Validated, Animal Free, ≥90%(SDS-PAGE&SEC-HPLC), See COA
Especies hospedadoras
Human
Especificidad
TACSTD2
Conjugación
MC-GGFG-DXd
Grado
Animal Free, Azide Free, Carrier Free, ExactAb™, Low Endotoxin, Recombinant, Validated
Tipo de acción
INHIBITOR
Isotipo
Human IgG1
Tipo de cadena ligera
kappa
SDS-PAGE
149.3 kDa
Método de purificación
Protein A purified
Pureza
>90% (SDS-PAGE&SEC)
Concentración
See COA
CAS
2238831-60-0
Almacenamiento y envío
Forma
Liquid
Condiciones de almacenamiento de almacenamiento
Store at -80°C,Avoid repeated freezing and thawing
Enviado en
Dry ice packs + Cold packs
Estabilidad y almacenamiento
Store at -80℃ for 24 months. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.
Imágenes

Datopotamab deruxtecan (anti-TROP2) (Ab183314) - Flow Cytometry
Flow Cytometry analysis of MCF-7 cells labelling TROP2 (red) with Datopotamab deruxtecan (anti-TROP2) (Ab183314). Goat Anti-Human IgG (PE) (Ab175838) at a dilution of 1/1000 was used as the secondary antibody. Blue - Isotype control, human IgG (Ab170213). Black - Unlabelled control, cells without incubation with primary antibody.

Datopotamab deruxtecan (anti-TROP2) (Ab183314) - ELISA
Immobilized rhTROP2(ECD)-chis at 2.0 μg/mL can bind Datopotamab deruxtecan (anti-TROP2) (Ab183314) with the EC ₅₀  of 7.22 ng/mL.​

Datopotamab deruxtecan (anti-TROP2) (Ab183314) - HIC
The drug-to-antibody ratio (DAR) of the Datopotamab deruxtecan (anti-TROP2) (Ab183314) is 4.0.

The purity of Datopotamab deruxtecan (anti-TROP2) (Ab183314) is more than 95% verified by HPLC.

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Objetivos asociados (humanos)
TACSTD2 Tclin Tumor-associated calcium signal transducer 2 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot NumberCertificate TypeFechaArticulo
ZJ24F0505657Certificate of AnalysisMar 17, 2026 Ab183314
ZJ24F0505658Certificate of AnalysisMar 17, 2026 Ab183314
ZJ24F0505659Certificate of AnalysisMar 17, 2026 Ab183314
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