LM22A-4 - 10mM in DMSO , CAS No.37988-18-4

CAS: 37988-18-4 Cat. No.: L423720 Peso molecular: 339.34
Disponible para pedir
GRADE & PURITY 10mM in DMSO
Synonyms
LM 22A4 | LM22a4 | LM-22A4 | LM22A-4 | N1,N3,N5-Tris(2-hydroxyethyl)-1,3,5-benzenetricarboxamide | 5GCL3P6AF5 | N,N',N''-Tris(2-hydroxyethyl)-1,3,5-benzenetricarboxamide | N,N',N''Tris(2-hydroxyethyl)-1,3,5-benzenetricarboxamide | SCHEMBL3321012 | 1,3,5-B
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
1ml
L423720-1ml
2

88,90US$

104,90US$
Guardar 16,00 US$ (15.25%)
Enter a quantity for the sizes you want to add.
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Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Shipped at room temperature. Store at -20°C.


Application

LM22A-4 has been used as a component of dissociation medium for mouse embryonic stem cells (mESC) and human embryonic stem (hESC) aggregates.

Specifications

Sinónimos
LM 22A4 | LM22a4 | LM-22A4 | LM22A-4 | N1, N3, N5-Tris(2-hydroxyethyl)-1, 3, 5-benzenetricarboxamide | 5GCL3P6AF5 | N, N', N''-Tris(2-hydroxyethyl)-1, 3, 5-benzenetricarboxamide | N, N', N''Tris(2-hydroxyethyl)-1, 3, 5-benzenetricarboxamide | SCHEMBL3321012 | 1, 3, 5-B
Especificaciones y pureza
10mM in DMSO
Mecanismos bioquímicos y fisiológicos
Small molecule BDNF mimetic displaying neurotrophic activity. Partial agonist at TrkB, activating TrkB signaling. Displaces BDNF (IC 50 = 47 nM) in binding assays.\xa0Prevents neuronal degeneration with equal efficacy to that of BDNF in in vitro models of
Condiciones de almacenamiento de almacenamiento
Store at -80°C
Enviado en
Dry ice packs + Cold packs
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Tipo de acción
AGONIST
Nombres e identificadores
Sonrisas canónicasC1=C(C=C(C=C1C(=O)NCCO)C(=O)NCCO)C(=O)NCCO
IUPAC Name1-N,3-N,5-N-tris(2-hydroxyethyl)benzene-1,3,5-tricarboxamide
InChIKeyRGWJKANXFYJKHN-UHFFFAOYSA-N
INCHI1S/C15H21N3O6/c19-4-1-16-13(22)10-7-11(14(23)17-2-5-20)9-12(8-10)15(24)18-3-6-21/h7-9,19-21H,1-6H2,(H,16,22)(H,17,23)(H,18,24)
Isómeros SMILES C1=C(C=C(C=C1C(=O)NCCO)C(=O)NCCO)C(=O)NCCO
Peso molecular 339.34
Reaxy-Rn 2398310
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2398310&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
ClaseBenzene and substituted derivatives
SubclassBenzoic acids and derivatives
Intermediate Tree Nodes Not available
Direct ParentBenzamides
Alternative Parents N-acylethanolamines  Benzoyl derivatives  Secondary carboxylic acid amides  Primary alcohols  Organopnictogen compounds  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAromatic homomonocyclic compounds
Substituents Benzamide - Benzoyl - N-acylethanolamine - Carboxamide group - Secondary carboxylic acid amide - Alkanolamine - Carboxylic acid derivative - Alcohol - Organooxygen compound - Organonitrogen compound - Primary alcohol - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic oxygen compound - Organic nitrogen compound - Aromatic homomonocyclic compound
DescripciónThis compound belongs to the class of organic compounds known as benzamides. These are organic compounds containing a carboxamido substituent attached to a benzene ring.
External Descriptors Not available
Estructura 3D
Modelo de Estructura Química Interactiva





Objetivos asociados (no humanos)
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propiedades químicas y físicas
Peso molecular339.340 g/mol
XLogP3-2.300
Hydrogen Bond Donor Count6
Hydrogen Bond Acceptor Count6
Rotatable Bond Count9
Exact Mass339.143 Da
Monoisotopic Mass339.143 Da
Topological Polar Surface Area148.000 Ų
Heavy Atom Count24
Formal Charge0
Complexity358.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Calculadoras de soluciones
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