Determine the necessary mass, volume, or concentration for preparing a solution.
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≥97% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Conservar a -20°C Ships Hielera + almohadillas de hielo Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 38 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
La lomefloxacina es un antibiótico quinolónico de amplio espectro, con actividad antimicrobiana. Lomefloxacino se utiliza para la investigación de la bronquitis, infección del tracto urinario, conjuntivitis, otitis externa y otitis media.
| Pubchem Sid | 504750731 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504750731 |
| Sonrisas canónicas | CCN1C=C(C(=O)C2=CC(=C(C(=C21)F)N3CCNC(C3)C)F)C(=O)O |
| IUPAC Name | 1-ethyl-6,8-difluoro-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid |
| InChIKey | ZEKZLJVOYLTDKK-UHFFFAOYSA-N |
| INCHI | 1S/C17H19F2N3O3/c1-3-21-8-11(17(24)25)16(23)10-6-12(18)15(13(19)14(10)21)22-5-4-20-9(2)7-22/h6,8-9,20H,3-5,7H2,1-2H3,(H,24,25) |
| Isómeros SMILES | CCN1C=C(C(=O)C2=CC(=C(C(=C21)F)N3CCNC(C3)C)F)C(=O)O |
| Peso molecular | 353.37 |
| Reaxy-Rn | 4210041 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=4210041&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Organoheterocyclic compounds |
| Clase | Quinolines and derivatives |
| Subclass | Quinoline carboxylic acids |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Quinoline carboxylic acids |
| Alternative Parents | Fluoroquinolones N-arylpiperazines Haloquinolines Hydroquinolones Aminoquinolines and derivatives Hydroquinolines Pyridinecarboxylic acids Dialkylarylamines Benzenoids Aryl fluorides Heteroaromatic compounds Vinylogous amides Amino acids Azacyclic compounds Monocarboxylic acids and derivatives Dialkylamines Carboxylic acids Hydrocarbon derivatives Organic oxides Organofluorides Organooxygen compounds Organopnictogen compounds |
| Molecular Framework | Aromatic heteropolycyclic compounds |
| Substituents | Quinoline-3-carboxylic acid - Fluoroquinolone - N-arylpiperazine - Aminoquinoline - Haloquinoline - Dihydroquinolone - Dihydroquinoline - Pyridine carboxylic acid - Pyridine carboxylic acid or derivatives - Tertiary aliphatic/aromatic amine - Dialkylarylamine - Aryl fluoride - Aryl halide - 1,4-diazinane - Piperazine - Pyridine - Benzenoid - Vinylogous amide - Heteroaromatic compound - Amino acid or derivatives - Amino acid - Tertiary amine - Azacycle - Secondary amine - Carboxylic acid derivative - Monocarboxylic acid or derivatives - Carboxylic acid - Secondary aliphatic amine - Amine - Organic oxygen compound - Organic nitrogen compound - Organopnictogen compound - Organic oxide - Organohalogen compound - Organofluoride - Organonitrogen compound - Organooxygen compound - Hydrocarbon derivative - Aromatic heteropolycyclic compound |
| Descripción | This compound belongs to the class of organic compounds known as quinoline carboxylic acids. These are quinolines in which the quinoline ring system is substituted by a carboxyl group at one or more positions. |
| External Descriptors | N-arylpiperazine - quinolone antibiotic - fluoroquinolone antibiotic - quinolone - quinolinemonocarboxylic acid |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Fecha | Articulo |
|---|---|---|---|
| Certificate of Analysis | Aug 12, 2025 | L305054 | |
| Certificate of Analysis | Aug 12, 2025 | L305054 | |
| Certificate of Analysis | Aug 12, 2025 | L305054 | |
| Certificate of Analysis | Aug 12, 2025 | L305054 | |
| Certificate of Analysis | Aug 12, 2025 | L305054 | |
| Certificate of Analysis | Sep 05, 2024 | L305054 | |
| Certificate of Analysis | Sep 05, 2024 | L305054 | |
| Certificate of Analysis | Sep 05, 2024 | L305054 | |
| Certificate of Analysis | Sep 05, 2024 | L305054 |
| Peso molecular | 351.350 g/mol |
|---|---|
| XLogP3 | -0.800 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 8 |
| Rotatable Bond Count | 3 |
| Exact Mass | 351.139 Da |
| Monoisotopic Mass | 351.139 Da |
| Topological Polar Surface Area | 72.900 Ų |
| Heavy Atom Count | 25 |
| Formal Charge | 0 |
| Complexity | 585.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 1 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
| 1. Li Zhili, Jiang Tianxiang, Huo Hanxin, Zhang Yizhong, Wang Xunliang, Guo Jian, Ma Yuhui. (2023) Magnetic activated carbon from spent coffee grounds: iron-catalyzed CO2 activation mechanism and adsorption of antibiotic lomefloxacin from aqueous medium. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, [PMID:38102422] [10.1007/s11356-023-31455-y] |
| 2. Xiaofei Fu, Junwu Tao, Zizhou Zhao, Siwen Sun, Lin Zhao, Zuming He, Yong Gao, Yongmei Xia. (2023) Interfacial S–O bonds specifically boost Z-scheme charge separation in a CuInS2/In2O3 heterojunction for efficient photocatalytic activity. RSC Advances, 13 (12): (8227-8237). [PMID:36922941] [10.1039/D3RA00043E] |
| 3. Wang Jiarui, Feng Juanjuan, Sun Min, Lian Yujing, Wang Minglin, Qiao Luqin. (2022) Sulfonic acid-functionalized covalent organic frameworks as the coating for stir bar sorptive extraction of fluoroquinolones in milk samples. MICROCHIMICA ACTA, 190 (1): (1-9). [PMID:36469152] [10.1007/s00604-022-05534-9] |
| 4. Yunhe Li, Hua Li, Siyuan Jiang, Yuerong Zhou, Dongran Cao, Xinrong Che, Ying Yang, Jiangwei Shang, Xiuwen Cheng. (2022) Enhanced adsorption for fluoroquinolones by MnOx-modified palygorskite composites: Preparation, properties and mechanism. SEPARATION AND PURIFICATION TECHNOLOGY, [PMID:] [10.1016/j.seppur.2022.121468] |
| 5. Xinyi Zhang, Yingjie Gao, Yunhe Li, Yuerong Zhou, Haiyan Ma, Jiangwei Shang, Xiuwen Cheng. (2022) Synthesis of magnetic NiFe2O4/CuS activator for degradation of lomefloxacin via the activation of peroxymonosulfate under simulated sunlight illumination. SEPARATION AND PURIFICATION TECHNOLOGY, [PMID:] [10.1016/j.seppur.2022.120664] |
| 6. Jin Yuting, Yan Rongfang, Wang Shuo, Wang Xianghong, Zhang Xuemei, Tang Yiwei. (2022) Dipeptide nanoparticle and aptamer-based hybrid fluorescence platform for enrofloxacin determination. MICROCHIMICA ACTA, 189 (3): (1-8). [PMID:35147788] [10.1007/s00604-022-05182-z] |
| 7. Ruonan Guo, Ying Chen, Bingrui Liu, Ying Han, Jianfeng Gou, Xiuwen Cheng. (2021) Catalytic degradation of lomefloxacin by photo-assisted persulfate activation on natural hematite: Performance and mechanism. CHINESE CHEMICAL LETTERS, [PMID:] [10.1016/j.cclet.2021.11.061] |
| 8. Cuizhu Ye, Xingguang Chen, Dong Zhang, Junjun Xu, Huiting Xi, Tiantian Wu, Danwen Deng, Chunhong Xiong, Jinsheng Zhang, Ganhui Huang. (2021) Study on the properties and reaction mechanism of polypyrrole@norfloxacin molecularly imprinted electrochemical sensor based on three-dimensional CoFe-MOFs/AuNPs. ELECTROCHIMICA ACTA, [PMID:] [10.1016/j.electacta.2021.138174] |
| 9. Zhijia Zhu, Chenmiao Zhu, Ruiying Yang, Lingfeng Yan, Chunyan Hu, Baojiang Liu. (2021) Fabrication of 3D Bi5O7I/BiOIO3 heterojunction material with enhanced photocatalytic activity towards tetracycline antibiotics. SEPARATION AND PURIFICATION TECHNOLOGY, [PMID:] [10.1016/j.seppur.2021.118522] |
| 10. Xiangning Han, Hong Lin, Limin Cao, Xiangfeng Chen, Luefeng Wang, Hongwei Zheng, Ziang Zhang, Tushar Ramesh Pavase, Sai Wang, Xun Sun, Jianxin Sui. (2020) Hapten-Branched Polyethylenimine as a New Antigen Affinity Ligand to Purify Antibodies with High Efficiency and Specificity. ACS Applied Materials & Interfaces, [PMID:33319977] [10.1021/acsami.0c15586] |
| 11. Meng Zhang, Jie Chen, Faqiong Zhao, Baizhao Zeng. (2020) Determination of fluoroquinolones in foods using ionic liquid modified Fe3O4/MWCNTs as the adsorbent for magnetic solid phase extraction coupled with HPLC. Analytical Methods, 12 (36): (4457-4465). [PMID:32856643] [10.1039/D0AY01045F] |
| 12. Kaili Yu, Mei-E. Yue, Jie Xu, Ting-Fu Jiang. (2020) Determination of fluoroquinolones in milk, honey and water samples by salting out-assisted dispersive liquid-liquid microextraction based on deep eutectic solvent combined with MECC. FOOD CHEMISTRY, [PMID:32622188] [10.1016/j.foodchem.2020.127371] |
| 13. Ruonan Guo, Ying Chen, Li-chao Nengzi, Lezu Meng, Qingqing Song, Jianfeng Gou, Xiuwen Cheng. (2020) In situ preparation of carbon-based Cu-Fe oxide nanoparticles from CuFe Prussian blue analogues for the photo-assisted heterogeneous peroxymonosulfate activation process to remove lomefloxacin. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2020.125556] |
| 14. Huixuan Zhang, Li-chao Nengzi, Xiaoling Li, Zhongjuan Wang, Bo Li, Lichen Liu, Xiuwen Cheng. (2020) Construction of CuBi2O4/MnO2 composite as Z-scheme photoactivator of peroxymonosulfate for degradation of antibiotics. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2020.124011] |
| 15. Qiuling Ma, Li-chao Nengzi, Bo Li, Zhongjuan Wang, Lichen Liu, Xiuwen Cheng. (2019) Heterogeneously catalyzed persulfate with activated carbon coated with CoFe layered double hydroxide (AC@CoFe-LDH) for the degradation of lomefloxacin. SEPARATION AND PURIFICATION TECHNOLOGY, [PMID:] [10.1016/j.seppur.2019.116204] |
| 16. Huixuan Zhang, Li-chao Nengzi, Zhongjuan Wang, Xinyi Zhang, Bo Li, Xiuwen Cheng. (2019) Construction of Bi2O3/CuNiFe LDHs composite and its enhanced photocatalytic degradation of lomefloxacin with persulfate under simulated sunlight. JOURNAL OF HAZARDOUS MATERIALS, [PMID:31563046] [10.1016/j.jhazmat.2019.121236] |
| 17. Yang-Zi Ouyang, Hai-Long Wu, Huan Fang, Tong Wang, Xiao-Dong Sun, Yue-Yue Chang, Yu-Jie Ding, Ru-Qin Yu. (2019) Rapid and simultaneous determination of three fluoroquinolones in animal-derived foods using excitation-emission matrix fluorescence coupled with second-order calibration method. SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, [PMID:31437766] [10.1016/j.saa.2019.117458] |
| 18. Huixuan Zhang, Yingyang Song, Li-chao Nengzi, Jianfeng Gou, Bo Li, Xiuwen Cheng. (2019) Activation of persulfate by a novel magnetic CuFe2O4/Bi2O3 composite for lomefloxacin degradation. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2019.122362] |
| 19. Da-Qi Cao, Wen-Yu Yang, Zhen Wang, Xiao-Di Hao. (2019) Role of extracellular polymeric substance in adsorption of quinolone antibiotics by microbial cells in excess sludge. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2019.03.230] |
| 20. Huixuan Zhang, Jinning Wang, Xinyi Zhang, Bo Li, Xiuwen Cheng. (2019) Enhanced removal of lomefloxacin based on peroxymonosulfate activation by Co3O4/δ-FeOOH composite. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2019.03.132] |
| 21. Huikai Shao, Haibo Zhou, Tingting Zhang, Xianglong Zhao, Zhengjin Jiang, Qiqin Wang. (2018) Preparation of molecularly imprinted hybrid monoliths for the selective detection of fluoroquinolones in infant formula powders. JOURNAL OF CHROMATOGRAPHY A, [PMID:30587346] [10.1016/j.chroma.2018.12.038] |
| 22. Chang Liu, Diandian Deng, Di Xu, Kang Wu, Hong Yang, Kang Zhao, Jianguo Li, Anping Deng. (2018) Development of a monoclonal antibody based-ELISA for the detection of chloramphenicol in shrimp, feed and milk samples and validation by LC-MS/MS coupled with immunoaffinity clean-up. Analytical Methods, 11 (4): (507-516). [PMID:] [10.1039/C8AY02284D] |
| 23. Suyu Ren, Jing Tao, Feng Tan, Ying Cui, Xiaona Li, Jingwen Chen, Xin He, Yi Wang. (2018) Diffusive gradients in thin films based on MOF-derived porous carbon binding gel for in-situ measurement of antibiotics in waters. SCIENCE OF THE TOTAL ENVIRONMENT, [PMID:30029123] [10.1016/j.scitotenv.2018.07.013] |
| 24. Fengliang Wang, Yiping Feng, Ping Chen, Yingfei Wang, Yuehan Su, Qianxin Zhang, Yongqin Zeng, Zhijie Xie, Haijin Liu, Yang Liu, Wenying Lv, Guoguang Liu. (2018) Photocatalytic degradation of fluoroquinolone antibiotics using ordered mesoporous g-C3N4 under simulated sunlight irradiation: Kinetics, mechanism, and antibacterial activity elimination. APPLIED CATALYSIS B-ENVIRONMENTAL, [PMID:] [10.1016/j.apcatb.2018.01.024] |
| 25. Yingfei Wang, Fengliang Wang, Yiping Feng, Zhijie Xie, Qianxin Zhang, Xiaoyu Jin, Haijin Liu, Yang Liu, Wenying Lv, Guoguang Liu. (2017) Facile synthesis of carbon quantum dots loaded with mesoporous g-C3N4 for synergistic absorption and visible light photodegradation of fluoroquinolone antibiotics. DALTON TRANSACTIONS, 47 (4): (1284-1293). [PMID:29299582] [10.1039/C7DT04360K] |
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