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Loreclezole - Moligand™, ≥98% , CAS No.117857-45-1

CAS: 117857-45-1 Cat. No.: L337898 Peso molecular: 274.53
COA
Loreclezole - Moligand™, ≥98% CAS No(117857-45-1) by Aladdin Scientific
Disponible para pedir
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥98%
Synonyms
HY-105272 | BS-14505 | Loreclezole [USAN:INN:BAN] | 6DJ32STZ5W | DTXSID6048252 | LORECLEZOLE [USAN] | R 72063 | Loreclezole [INN-Español] | Loreclezole | GTPL5466 | LORECLEZOLE [INN] | (Z)-1-(.beta.,2,4-Tricloroestirilo)-1H-1,2,4-triazol
Storage
Conservar a -20°C,Desecado
Shipped In
Hielera + almohadillas de hielo
★
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
1mg
L337898-1mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.

9,90US$

14,90US$
Guardar 5,00 US$ (33.56%)
5mg
L337898-5mg
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32,90US$

49,90US$
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10mg
L337898-10mg
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59,90US$

89,90US$
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25mg
L337898-25mg
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129,90US$

194,90US$
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50mg
L337898-50mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.

233,90US$

350,90US$
Guardar 117,00 US$ (33.34%)
100mg
L337898-100mg
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.

419,90US$

629,90US$
Guardar 210,00 US$ (33.34%)
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♡ Lista de deseos ⇅ Añadir para comparar ⎙ Print page
SDS
Safety data
COA
Certificate
DS
Datasheet
SP
Spec sheet
Descripción general Specifications Nombres e identificadores Documentation Advanced Data Taxonomic Classification Estructura 3D Objetivos asociados (humanos) Objetivos asociados (no humanos) Mecanismos de acción Certificados (CoA, COO, BSE/TSE y tabla de análisis) Propiedades químicas y físicas Calculadoras de soluciones Reseñas
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Why this grade

Moligand™, ≥98% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Conservar a -20°C,Desecado Ships Hielera + almohadillas de hielo Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

El clorhidrato de loreclezol es un agonista selectivo de los receptores GABA. Modulador alostérico positivo de los receptores que contienen subunidades β2 o β3. También actúa como modulador negativo en un nuevo sitio regulador, aumentando la sensibilización de los receptores GABA. Inhibe los receptores GABA-C homoméricos ρ1.

Specifications

Sinónimos
HY-105272 | BS-14505 | Loreclezole [USAN:INN:BAN] | 6DJ32STZ5W | DTXSID6048252 | LORECLEZOLE [USAN] | R 72063 | Loreclezole [INN-Español] | Loreclezole | GTPL5466 | LORECLEZOLE [INN] | (Z)-1-(.beta., 2, 4-Tricloroestirilo)-1H-1, 2, 4-triazol
Especificaciones y pureza
Moligand™, ≥98%
Condiciones de almacenamiento de almacenamiento
Conservar a -20°C, Desecado
Enviado en
Hielera + almohadillas de hielo
Grado
Moligand™
Tipo de acción
AGONIST
Pureza
≥98%
Nombres e identificadores
Sonrisas canónicasC1=CC(=C(C=C1Cl)Cl)C(=CN2C=NC=N2)Cl
IUPAC Name1-[(Z)-2-chloro-2-(2,4-dichlorophenyl)ethenyl]-1,2,4-triazole
InChIKeyXGLHZTBDUXXHOM-WMZJFQQLSA-N
INCHI1S/C10H6Cl3N3/c11-7-1-2-8(9(12)3-7)10(13)4-16-6-14-5-15-16/h1-6H/b10-4-
Isómeros SMILES C1=CC(=C(C=C1Cl)Cl)/C(=C/N2C=NC=N2)/Cl
RTECS XZ4382000
Peso molecular 274.53

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

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📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassBenzenoids
ClaseBenzene and substituted derivatives
SubclassHalobenzenes
Intermediate Tree Nodes Chlorobenzenes
Direct ParentDichlorobenzenes
Alternative Parents Styrenes  Aryl chlorides  Triazoles  Heteroaromatic compounds  Vinyl chlorides  Chloroalkenes  Azacyclic compounds  Organopnictogen compounds  Organonitrogen compounds  Organochlorides  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteromonocyclic compounds
Substituents 1,3-dichlorobenzene - Styrene - Aryl chloride - Aryl halide - Azole - Heteroaromatic compound - 1,2,4-triazole - Azacycle - Chloroalkene - Haloalkene - Vinyl chloride - Vinyl halide - Organoheterocyclic compound - Organochloride - Organonitrogen compound - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organohalogen compound - Aromatic heteromonocyclic compound
DescripciónThis compound belongs to the class of organic compounds known as dichlorobenzenes. These are compounds containing a benzene with exactly two chlorine atoms attached to it.
External Descriptors Not available
Estructura 3D
Modelo de Estructura Química Interactiva





Objetivos asociados (humanos)
CYP1A2 Tchem Cytochrome P450 1A2 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
CYP3A4 Tclin Cytochrome P450 3A4 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
TSHR Tclin Thyroid stimulating hormone receptor (29986 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2D6 Tclin Cytochrome P450 2D6 (33882 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP1A2 Tchem Cytochrome P450 1A2 (26471 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2C9 Tchem Cytochrome P450 2C9 (32119 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2C19 Tchem Cytochrome P450 2C19 (29246 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HPGD Tchem 15-hydroxyprostaglandin dehydrogenase [NAD+] (24926 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GABRA1 Tclin GABA-A receptor; alpha-1/beta-3/gamma-2 (1565 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Objetivos asociados (no humanos)
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
lef Anthrax lethal factor (7585 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mapt Microtubule-associated protein tau (6 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Gabrg2 Gamma-aminobutyric acid receptor subunit alpha-6/beta-3/gamma-2 (184 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propiedades químicas y físicas
SolubilidadSoluble in ethanol (5 mM with gentle warming), and DMSO (5 mM with gentle warming).
Índice de refracciónn20D1.65 (Predicted)
Punto de ebullición (°C)442.7° C at 760 mmHg (Predicted)
Peso molecular274.500 g/mol
XLogP33.800
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count2
Exact Mass272.963 Da
Monoisotopic Mass272.963 Da
Topological Polar Surface Area30.700 Ų
Heavy Atom Count16
Formal Charge0
Complexity272.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds1
Covalently-Bonded Unit Count1
Calculadoras de soluciones
Reseñas

Reseñas de cliente

Need help choosing the grade?

Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

View Moligand™ grade guide →
Bulk & Custom Packaging Need larger quantities or custom specifications? Contact our team for a tailored quote.

View related series

GABA Receptor (186) Ion channel (4039) Membrane Transporter/Ion Channel (1841) Neuronal Signaling (3365)
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