Luteolinidin chloride - ≥98% , CAS No.1154-78-5

CAS: 1154-78-5 Cat. No.: L648263 Peso molecular: 306.70 Número EC: 601-367-5 PubChem CID: 6451196

GRADE & PURITY ≥98%

Synonyms

1-Benzopyrylium, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-, chloride | 2-(3,4-dihydroxyphenyl)chromenylium-5,7-diol chloride | DTXSID20921728 | HY-129997 | Luteolinidol chloride | AKOS040760536 | 2-(3,4-dihydroxyphenyl)chromenylium-5,7-diol;chloride | 2-(3,4

Storage

Store at 2-8°C,Protected from light,Desiccated

Shipped In

Wet ice

Descripción general

Luteolinidin is a natural deoxyanthocyanidin, isolated from Sorghum bicolor Luteolinidin is a potent CD38 inhibitor which can protect the heart against I/R injury with preservation of eNOS function and prevention of endothelial dysfunction in vivo .

Form:Solid

IC50& Target:Ki: 11 μM (CD 38)

Specifications

Sinónimos

1-Benzopyrylium, 2-(3, 4-dihydroxyphenyl)-5, 7-dihydroxy-, chloride | 2-(3, 4-dihydroxyphenyl)chromenylium-5, 7-diol chloride | DTXSID20921728 | HY-129997 | Luteolinidol chloride | AKOS040760536 | 2-(3, 4-dihydroxyphenyl)chromenylium-5, 7-diol;chloride | 2-(3, 4

Especificaciones y pureza

≥98%

Mecanismos bioquímicos y fisiológicos

Luteolinidin is a natural deoxyanthocyanidin, isolated from Sorghum bicolor. Luteolinidin is a potent CD38 inhibitor which can protect the heart against I/R injury with preservation of eNOS function and prevention of endothelial dysfunction in vivo [

Condiciones de almacenamiento de almacenamiento

Store at 2-8°C, Protected from light, Desiccated

Enviado en

Wet ice

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Tipo de acción

INHIBITOR

Pureza

≥98%

Nombres e identificadores

• Sonrisas canónicas: C1=CC(=C(C=C1C2=[O+]C3=CC(=CC(=C3C=C2)O)O)O)O.[Cl-]
• IUPAC Name: 2-(3,4-dihydroxyphenyl)chromenylium-5,7-diol;chloride
• InChIKey: MMAGHFOHXGFQRZ-UHFFFAOYSA-N
• INCHI: 1S/C15H10O5.ClH/c16-9-6-12(18)10-2-4-14(20-15(10)7-9)8-1-3-11(17)13(19)5-8;/h1-7H,(H3-,16,17,18,19);1H
• Isómeros SMILES: C1=CC(=C(C=C1C2=[O+]C3=CC(=CC(=C3C=C2)O)O)O)O.[Cl-]
• CAS alternativo: 1154-78-5
• PubChem CID: 6451196
• Términos de entrada MeSH: luteolinidin
• Peso molecular: 306.70

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Phenylpropanoids and polyketides
    • Clase Flavonoids
      • Subclass Hydroxyflavonoids

• Kingdom: Organic compounds
• Superclass: Phenylpropanoids and polyketides
• Clase: Flavonoids
• Subclass: Hydroxyflavonoids
• Intermediate Tree Nodes: Not available
• Direct Parent: 7-hydroxyflavonoids
• Alternative Parents: 5-hydroxyflavonoids 4'-hydroxyflavonoids 3'-hydroxyflavonoids Anthocyanidins 1-benzopyrans Catechols 1-hydroxy-4-unsubstituted benzenoids 1-hydroxy-2-unsubstituted benzenoids Benzene and substituted derivatives Heteroaromatic compounds Oxacyclic compounds Organooxygen compounds Organic zwitterions Organic chloride salts Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: 3'-hydroxyflavonoid - 4'-hydroxyflavonoid - 5-hydroxyflavonoid - 7-hydroxyflavonoid - Anthocyanidin - 1-benzopyran - Benzopyran - Catechol - 1-hydroxy-4-unsubstituted benzenoid - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Benzenoid - Monocyclic benzene moiety - Heteroaromatic compound - Oxacycle - Organoheterocyclic compound - Organic oxygen compound - Organooxygen compound - Organic zwitterion - Organic salt - Organic chloride salt - Hydrocarbon derivative - Aromatic heteropolycyclic compound
• Descripción: This compound belongs to the class of organic compounds known as 7-hydroxyflavonoids. These are flavonoids that bear one hydroxyl group at the C-7 position of the flavonoid skeleton.
• External Descriptors: anthocyanidin chloride

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Solubilidad: DMSO : 50 mg/mL (163.03 mM; Need ultrasonic)
• Peso molecular: 306.700 g/mol
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 1
• Exact Mass: 306.03 Da
• Monoisotopic Mass: 306.03 Da
• Topological Polar Surface Area: 81.900 Ų
• Heavy Atom Count: 21
• Formal Charge: 0
• Complexity: 336.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

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