LY2109761 - Moligand™, 10 mM in DMSO , CAS No.700874-71-1

CAS: 700874-71-1 Cat. No.: L1495300 Peso molecular: 441.52
Disponible para pedir
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10 mM in DMSO
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
1ml
L1495300-1ml
8-12 wks(?) Production requires sourcing of materials. We appreciate your patience and understanding.
92,90US$
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Why this grade

Moligand™, 10 mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 2 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

LY2109761 is an orally active, selective TGF-β receptor type I/II inhibitor with K i s of 38 nM and 300 nM, respectively.

Specifications

Especificaciones y pureza
Moligand™, 10 mM in DMSO
Condiciones de almacenamiento de almacenamiento
Store at -80°C
Enviado en
Dry ice packs + Cold packs
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Grado
Moligand™
Tipo de acción
INHIBITOR
Nombres e identificadores
Isómeros SMILES C1CC2=C(C(=NN2C1)C3=CC=CC=N3)C4=C5C=CC(=CC5=NC=C4)OCCN6CCOCC6
Peso molecular 441.52
Reaxy-Rn 14275148
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=14275148&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Citations of This Product
Referencias
1. Dai-Yu Sun, Jia-Qi Wu, Zhi-Heng He, Ming-Fang He, Hong-Bin Sun.  (2019)  Cancer-associated fibroblast regulate proliferation and migration of prostate cancer cells through TGF-β signaling pathway.  LIFE SCIENCES,      [PMID:31465732] [10.1016/j.lfs.2019.116791]
2. Junjuan Lu, Caihong Liu, Ting Yuan, Honghui Yang, Li Zhang.  (2025)  Neutrophil-derived exosomal thrombospondin-1 exacerbates endothelial progenitor cell senescence and lung injury via TGF-β/SMAD signaling in COPD.  Translational Research,      [PMID:41412416] [10.1016/j.trsl.2025.12.004]
Calculadoras de soluciones
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