Macbecin I , CAS No.73341-72-7

CAS: 73341-72-7 Cat. No.: M288197 Peso molecular: 558.67 PubChem CID: 24199491

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Macbecin I - CAS No(73341-72-7) by Aladdin Scientific

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Disponible para pedir

Synonyms

NSC330499 | NSC-330499 | [(4E,6Z,10Z)-13,14,17-Trimethoxy-4,8,10,12,16-pentamethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl] carbamate | Geldanamycin,17-didemethoxy-15-methoxy-6-methyl-11-O-methyl-, (6S,15R)- | Macbecin I

Storage

Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

Specifications Nombres e identificadores Documentation Advanced Data Estructura 3D Objetivos asociados (humanos) Mecanismos de acción Certificados (CoA, COO, BSE/TSE y tabla de análisis) Propiedades químicas y físicas Calculadoras de soluciones Reseñas

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Why this grade

for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -20°C,Desiccated Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Sinónimos

NSC330499 | NSC-330499 | [(4E, 6Z, 10Z)-13, 14, 17-Trimethoxy-4, 8, 10, 12, 16-pentamethyl-3, 20, 22-trioxo-2-azabicyclo[16.3.1]docosa-1(21), 4, 6, 10, 18-pentaen-9-yl] carbamate | Geldanamycin, 17-didemethoxy-15-methoxy-6-methyl-11-O-methyl-, (6S, 15R)- | Macbecin I

Mecanismos bioquímicos y fisiológicos

Ansamycin antibiotic compound that inhibits Hsp90 activity (IC50= 2μM) by binding to the ATP-binding site. Exhibits antitumor and cytocidal activities (IC50~ 0.4μM) by causing degradation of key oncogenic client proteins such as ErbB2 and cRaf1. Displays

Condiciones de almacenamiento de almacenamiento

Store at -20°C, Desiccated

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Tipo de acción

INHIBITOR

Nombres e identificadores

Sonrisas canónicas	CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C=C(C1OC)C2=O)C)C)OC(=O)N)C)C)OC)OC
IUPAC Name	[(4E,6Z,10Z)-13,14,17-trimethoxy-4,8,10,12,16-pentamethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-9-yl] carbamate
InChIKey	PLTGBUPHJAKFMA-FOKZELFKSA-N
INCHI	1S/C30H42N2O8/c1-16-10-9-11-17(2)29(35)32-23-15-21(33)14-22(25(23)34)27(38-7)20(5)13-24(37-6)28(39-8)19(4)12-18(3)26(16)40-30(31)36/h9-12,14-16,19-20,24,26-28H,13H2,1-8H3,(H2,31,36)(H,32,35)/b10-9-,17-11+,18-12-
Isómeros SMILES	CC1CC(C(C(/C=C(\C(C(/C=C\C=C(\C(=O)NC2=CC(=O)C=C(C1OC)C2=O)/C)C)OC(=O)N)/C)C)OC)OC
PubChem CID	24199491
Peso molecular	558.67

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

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✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

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📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Estructura 3D

Objetivos asociados (humanos)

A498 (42825 Activities)