Malonyl coenzyme A lithium salt - ≥90%(HPLC) , CAS No.108347-84-8

CAS: 108347-84-8 Cat. No.: M463170 Peso molecular: 853.58 (free acid basis)

GRADE & PURITY ≥90%(HPLC)

Synonyms

CID 16219642 | AKOS030255405 | DTXSID70585218 | Malonyl coenzyme A lithium salt | PUBCHEM_16219642

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Descripción general

Description

Malonyl coenzyme A lithium salt has been used:in Krebs Ringer bicarbonate medium for preincubation of trypsinized and re-suspended fibroblast for fatty acid oxidation assayin HEPES (4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid) buffer used for scintillation proximity assay for fatty acid synthaseas an internal standard in the reaction mixture used for succinyl-CoA ligase assay

Specifications

Sinónimos

CID 16219642 | AKOS030255405 | DTXSID70585218 | Malonyl coenzyme A lithium salt | PUBCHEM_16219642

Especificaciones y pureza

≥90%(HPLC)

Mecanismos bioquímicos y fisiológicos

Coenzyme A functions as an acyl group carrier, acetyl-CoA. Malonyl Coenzyme A is a coenzyme A derivative that is utilized in fatty acid and polyketide synthesis and in the transport of α-ketoglutarate across the mitochondrial membrane. Malonyl CoA is for

Condiciones de almacenamiento de almacenamiento

Store at -20°C

Enviado en

Ice chest + Ice pads

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Pureza

≥90%(HPLC)

Nombres e identificadores

• Sonrisas canónicas: [Li].CC(C)(COP(=O)(O)OP(=O)(O)OCC1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)OP(=O)(O)O)C(C(=O)NCCC(=O)NCCSC(=O)CC(=O)O)O
• InChIKey: OPIJLICRFQMMJH-UHFFFAOYSA-N
• INCHI: 1S/C24H38N7O19P3S.Li/c1-24(2,19(37)22(38)27-4-3-13(32)26-5-6-54-15(35)7-14(33)34)9-47-53(44,45)50-52(42,43)46-8-12-18(49-51(39,40)41)17(36)23(48-12)31-11-30-16-20(25)28-10-29-21(16)31;/h10-12,17-19,23,36-37H,3-9H2,1-2H3,(H,26,32)(H,27,38)(H,33,34)(H,42,43)(H,44,45)(H2,25,28,29)(H2,39,40,41)
• Isómeros SMILES: [Li].CC(C)(COP(=O)(O)OP(=O)(O)OCC1C(C(C(O1)N2C=NC3=C(N=CN=C32)N)O)OP(=O)(O)O)C(C(=O)NCCC(=O)NCCSC(=O)CC(=O)O)O
• CAS alternativo: 524-14-1
• Peso molecular: 853.58 (free acid basis)

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Lipids and lipid-like molecules
    • Clase Fatty Acyls
      • Subclass Fatty acyl thioesters

• Kingdom: Organic compounds
• Superclass: Lipids and lipid-like molecules
• Clase: Fatty Acyls
• Subclass: Fatty acyl thioesters
• Intermediate Tree Nodes: Not available
• Direct Parent: Acyl CoAs
• Alternative Parents: Coenzyme A and derivatives Purine ribonucleoside diphosphates Ribonucleoside 3'-phosphates Pentose phosphates Beta amino acids and derivatives Glycosylamines 6-aminopurines Monosaccharide phosphates Organic pyrophosphates Aminopyrimidines and derivatives Monoalkyl phosphates 1,3-dicarbonyl compounds Imidolactams N-acyl amines N-substituted imidazoles Tetrahydrofurans Heteroaromatic compounds Amino acids Carbothioic S-esters Secondary carboxylic acid amides Secondary alcohols Thioesters Organic alkali metal salts Carboxylic acids Sulfenyl compounds Oxacyclic compounds Azacyclic compounds Monocarboxylic acids and derivatives Organopnictogen compounds Organic oxides Hydrocarbon derivatives Primary amines
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Coenzyme a or derivatives - Purine ribonucleoside 3',5'-bisphosphate - Purine ribonucleoside bisphosphate - Purine ribonucleoside diphosphate - Ribonucleoside 3'-phosphate - Pentose phosphate - Pentose-5-phosphate - Beta amino acid or derivatives - Glycosyl compound - N-glycosyl compound - 6-aminopurine - Monosaccharide phosphate - Organic pyrophosphate - Pentose monosaccharide - Imidazopyrimidine - Purine - Aminopyrimidine - Monoalkyl phosphate - Alkyl phosphate - 1,3-dicarbonyl compound - Fatty amide - Monosaccharide - N-acyl-amine - N-substituted imidazole - Organic phosphoric acid derivative - Phosphoric acid ester - Imidolactam - Pyrimidine - Imidazole - Heteroaromatic compound - Tetrahydrofuran - Azole - Amino acid - Thiocarboxylic acid ester - Amino acid or derivatives - Carbothioic s-ester - Secondary carboxylic acid amide - Secondary alcohol - Carboxamide group - Oxacycle - Azacycle - Organic alkali metal salt - Organoheterocyclic compound - Monocarboxylic acid or derivatives - Carboxylic acid derivative - Thiocarboxylic acid or derivatives - Sulfenyl compound - Carboxylic acid - Carbonyl group - Amine - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organic nitrogen compound - Organic salt - Alcohol - Organonitrogen compound - Organooxygen compound - Organosulfur compound - Organic oxygen compound - Primary amine - Aromatic heteropolycyclic compound
• Descripción: This compound belongs to the class of organic compounds known as acyl coas. These are organic compounds containing a coenzyme A substructure linked to an acyl chain.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Solubilidad: H2O: soluble 50mg/mL protein, clear, colorless；PBS (pH 7.2): 10 mg/ml
• Peso molecular: 860.600 g/mol
• Hydrogen Bond Donor Count: 10
• Hydrogen Bond Acceptor Count: 24
• Rotatable Bond Count: 22
• Exact Mass: 860.132 Da
• Monoisotopic Mass: 860.132 Da
• Topological Polar Surface Area: 426.000 Ų
• Heavy Atom Count: 55
• Formal Charge: 0
• Complexity: 1490.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 5
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3