Determine the necessary mass, volume, or concentration for preparing a solution.
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≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at 2-8°C Ships Wet ice Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 24 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Malotilate, diisopropyl 1,3-dithiol-2-ylidenemalonate, is a drug used for the treatment of liver cirrhosis.
A hepatoprotective agent.
[1]. Comprehensive hazard, handling, storage, and regulatory compliance document. Lot-specific quality data. Enter your lot number to retrieve the exact COA. Full quality attributes and acceptance criteria for this grade. Taxonomy Tree Find and download the COA for your product by matching the lot number on the packaging. 1 results foundNombres e identificadores
Pubchem Sid 504750736 Pubchem Sid Url https://pubchem.ncbi.nlm.nih.gov/substance/504750736 Sonrisas canónicas CC(C)OC(=O)C(=C1SC=CS1)C(=O)OC(C)C IUPAC Name dipropan-2-yl 2-(1,3-dithiol-2-ylidene)propanedioate InChIKey YPIQVCUJEKAZCP-UHFFFAOYSA-N INCHI 1S/C12H16O4S2/c1-7(2)15-10(13)9(11(14)16-8(3)4)12-17-5-6-18-12/h5-8H,1-4H3 Isómeros SMILES CC(C)OC(=O)C(=C1SC=CS1)C(=O)OC(C)C RTECS OO0970000 Peso molecular 288.38 Reaxy-Rn 7481938 Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=7481938&ln= Documentation
📋 Safety Data Sheet (SDS)
✅ Certificate of Analysis (COA)
🔬 Specification Sheet
Advanced Data
Taxonomic Classification
Kingdom Organic compounds Superclass Organic acids and derivatives Clase Carboxylic acids and derivatives Subclass Dicarboxylic acids and derivatives Intermediate Tree Nodes Not available Direct Parent Dicarboxylic acids and derivatives Alternative Parents Vinylogous thioesters Enoate esters 1,3-dithioles Thioenol ethers Ketene acetals Organic oxides Hydrocarbon derivatives Carbonyl compounds Molecular Framework Aliphatic heteromonocyclic compounds Substituents Dicarboxylic acid or derivatives - Vinylogous thioester - 1,3-dithiole - Dithiole - Enoate ester - Alpha,beta-unsaturated carboxylic ester - Carboxylic acid ester - Thioenolether - Ketene acetal or derivatives - Organoheterocyclic compound - Carbonyl group - Organooxygen compound - Organic oxygen compound - Organic oxide - Hydrocarbon derivative - Aliphatic heteromonocyclic compound Descripción This compound belongs to the class of organic compounds known as dicarboxylic acids and derivatives. These are organic compounds containing exactly two carboxylic acid groups. External Descriptors Not available Estructura 3D
Objetivos asociados (humanos)
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Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID Activity Type Relation Activity value Units Action Type Journal PubMed Id doi Assay Aladdin ID Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
Lot Number Certificate Type Fecha Articulo
B1528011Certificate of Analysis Mar 20, 2026 M126891 Propiedades químicas y físicas
Solubilidad Soluble in DMSO (58 mg/ml at 25 °C), water (<1 mg/ml at 25 °C), and ethanol (58 mg/ml at 25 °C). Punto de fusión (°C) 61 °C Peso molecular 288.400 g/mol XLogP3 3.800 Hydrogen Bond Donor Count 0 Hydrogen Bond Acceptor Count 6 Rotatable Bond Count 6 Exact Mass 288.049 Da Monoisotopic Mass 288.049 Da Topological Polar Surface Area 103.000 Ų Heavy Atom Count 18 Formal Charge 0 Complexity 363.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1 Citations of This Product
Referencias
1. Hui Wang, Yuhan Xiong, Yi He, Lingru Kong, Lan Ding, Rui Wu, Xin-Lei Gao, Jie Ding, Nanqi Ren. (2023) Photocatalytic degradation of benzotriazole through synergy of electron donor–acceptor units and Au clusters in covalent organic frameworks. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2023.148309] 2. Xi Wang, Wenjing Zhu, Miao Xing, Haiyan Zhu, Enqing Chen, Jie Zhou. (2023) Matrine disrupts Nrf2/GPX4 antioxidant system and promotes hepatocyte ferroptosis. CHEMICO-BIOLOGICAL INTERACTIONS, [PMID:37716422] [10.1016/j.cbi.2023.110713] 3. Lu-Qing Xie, Sui Peng, Ya-Nan Xin, Bo Liu, Xin-Yu Jiang, Jin-Gang Yu. (2023) Preparation of three-dimensional 2-mercaptothiazoline modified GO aerogel for selective adsorption of Cu2+ in aqueous solution. Journal of Environmental Chemical Engineering, [PMID:] [10.1016/j.jece.2023.110332] 4. Kai Zheng, Jiaxiang Bai, Wanling Chen, Yaozeng Xu, Huilin Yang, Wei Li, Penghui Li, Liping Tong, Huaiyu Wang, Paul K. Chu, Dechun Geng. (2023) Multifunctional BPs/MT@PLGA-ALE Nanospheres for Treatment of Osteoporotic Fracture with Near-Infrared Irradiation. ADVANCED FUNCTIONAL MATERIALS, 33 (18): (2214126). [PMID:] [10.1002/adfm.202214126] 5. Wang Yamei, Xiao Dongdong, Tang Yang, Xia Yezhong, Zhong Yi, Zhang Linping, Sui Xiaofeng, Wang Bijia, Feng Xueling, Xu Hong, Mao Zhiping. (2022) Carboxymethyl cellulose-based injectable hydrogel loaded with a composite of melatonin and γ-cyclodextrin with antioxidant property for diabetic wound repair. CELLULOSE, 30 (3): (1791-1810). [PMID:] [10.1007/s10570-022-04981-0] 6. Si-wei Rao, Yuan-yuan Duan, Dong-sheng Zhao, Cheng-jun Liu, Shao-hua Xu, Dong Liang, Feng-xiang Zhang, Wei Shi. (2022) Integrative Analysis of Transcriptomic and Metabolomic Data for Identification of Pathways Related to Matrine-Induced Hepatotoxicity. CHEMICAL RESEARCH IN TOXICOLOGY, [PMID:36440846] [10.1021/acs.chemrestox.2c00264] 7. Guan Huanshuai, Kong Ning, Tian Run, Cao Ruomu, Liu Guanzhi, Li Yiyang, Wei Qilu, Jiao Ming, Lei Yutian, Xing Fangze, Tian Peng, Wang Kunzheng, Yang Pei. (2022) Melatonin increases bone mass in normal, perimenopausal, and postmenopausal osteoporotic rats via the promotion of osteogenesis. Journal of Translational Medicine, 20 (1): (1-15). [PMID:35296324] [10.1186/s12967-022-03341-7] 8. Yamei Wang, Dongdong Xiao, Hainan Yu, Ruiyu Ke, Songlin Shi, Yang Tang, Yi Zhong, Linping Zhang, Xiaofeng Sui, Bijia Wang, Xueling Feng, Hong Xu, Zhiping Mao. (2022) Asymmetric composite wound dressing with hydrophobic flexible bandage and tissue-adhesive hydrogel for joints skin wound healing. COMPOSITES PART B-ENGINEERING, [PMID:] [10.1016/j.compositesb.2022.109762] 9. Mengfan Cao, Yanjiao Zou, Yuanyuan Zhang, Ting Zeng, Qijin Wan, Guosong Lai, Nianjun Yang. (2022) Robust and selective electrochemical sensing of hazardous photographic developing agents using a MOF-derived 3D porous flower-like Co3O4@C/graphene nanoplate composite. ELECTROCHIMICA ACTA, [PMID:] [10.1016/j.electacta.2022.139967] 10. Chunji Jiang, Ziyue Ling, Yuanting Xu, Jianxu Bao, Lan Feng, Huitong Cheng, Weifeng Zhao, Changsheng Zhao. (2021) Long-term, synergistic and high-efficient antibacterial polyacrylonitrile nanofibrous membrane prepared by “one-pot” electrospinning process. JOURNAL OF COLLOID AND INTERFACE SCIENCE, [PMID:34863546] [10.1016/j.jcis.2021.11.075] 11. Feifei Wang, Wenqian Cai, Wenzhuo Shi, Haiwen Wu, Qian Shen, Yanan He, Song Cui, Lihui An. (2021) Single molecule real-time sequencing revealing novel insights on the response to estrogen and androgen exposure in freshwater snails. AQUATIC TOXICOLOGY, [PMID:34521059] [10.1016/j.aquatox.2021.105953] 12. Renren Sun, Haixia He, Yameng Wan, Yueru Wang, Liyuan Li, Jiao Sha, Gaoliang Jiang, Yu Li, Tao Li, Baozeng Ren. (2020) Solubility of melatonin in ethyl acetate + (N, N-dimethylformamide, 2-methoxyethanol, 2-ethoxyethanol and methanol): Determination, correlation, thermodynamic properties and Hansen solubility parameter at saturation. JOURNAL OF CHEMICAL THERMODYNAMICS, [PMID:] [10.1016/j.jct.2020.106372] 13. Zhiya Sun, Mei Long, Xinxuan Liu, Yi Zhang, Shunxiang Li, Limei Bai, Huaming Yang. (2020) Investigation of natural minerals for ulcerative colitis therapy. APPLIED CLAY SCIENCE, [PMID:] [10.1016/j.clay.2020.105436] 14. Kong Qinghong, Zhang Yi, Zhang Xin, Xiang Bing, Yi Yanzhu, Zhu Junyu, Zhang Feng, Zhu Jia, Zhang Junhao. (2019) Functionalized Montmorillonite Intercalation Iron Compounds for Improving Flame Retardancy of Epoxy Resin Nanocomposites. JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, 19 (9): (5803-5809). [PMID:30961742] [10.1166/jnn.2019.16540] 15. Xiang Li, Zhongzhen Liu, Lan Wei, Lianxi Huang, Qing Huang, Xiaoshan Jia. (2019) Comparison of Competitive and Synergistic Adsorption of Tetrabromobisphenol-A and Its Metabolites on Two Different Organic-Modified Clays. JOURNAL OF CHEMICAL AND ENGINEERING DATA, [PMID:] [10.1021/acs.jced.9b00164] 16. Yongcun Song, Songyan Wang, Li-Ye Yang, Di Yu, Yang-Guang Wang, Xiao-kun Ouyang. (2019) Facile fabrication of core–shell/bead-like ethylenediamine-functionalized Al-pillared montmorillonite/calcium alginate for As(V) ion adsorption. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, [PMID:30926490] [10.1016/j.ijbiomac.2019.03.172] 17. Yi Huang, Qi Tao, Dongzhi Hou, Sheng Hu, Shuangyan Tian, Yanzhong Chen, Ruyi Gui, Lingling Yang, Yao Wang. (2017) A novel ion-exchange carrier based upon liposome-encapsulated montmorillonite for ophthalmic delivery of betaxolol hydrochloride. International Journal of Nanomedicine, [PMID:28280338] [10.2147/IJN.S122747] 18. Qinhui Wang, Lei Shi, Xiuling Tang, Qingwei Wang, Xueliang Dang, Yan Zhang. (2014) Pharmacokinetic study of multiple active constituents from Kushen–Gancao Decoction after oral administration in rat by HPLC–MS/MS. JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, [PMID:24976484] [10.1016/j.jchromb.2014.05.038] 19. Jin Wang, Xiaoting Hong, Gangming Fang, Xuegang Zhang. (2024) Deep purification of pesticide waste salt containing high-concentration organic pollutants by ethanol solvents washing and heating treatment. Journal of Environmental Chemical Engineering, [PMID:] [10.1016/j.jece.2024.112480] 20. Peng Yi, Xiao Shu, Chenhui Wang, Mingfu Li, Yu Huang, Min Wu, Lijuan Zhang, Quan Chen. (2024) Formation of cation bridges and its promoting mechanism for sorption of sulfamethoxazole by montmorillonite. CHEMOSPHERE, [PMID:38582173] [10.1016/j.chemosphere.2024.141841] 21. Xiaotian Zhang, Yuxia Wu, Yang Zhang, Jin Zhang, Kunci Chen, Haiyang Liu, Qing Luo, Shuzhan Fei, Jian Zhao, Mi Ou. (2024) Molecular Characteristics, Expression Patterns, and Response of Insulin-like Growth Factors Gene Induced by Sex Steroid Hormones in Blotched Snakehead (Channa maculata). Fishes, 9 (4): (120). [PMID:] [10.3390/fishes9040120] 22. Tingting Chen, Zimei Wu, Qiaodan Hou, Yixin Mei, Kunkun Yang, Jing Xu, Lin Wang. (2024) The Dual Angiogenesis Effects via Nrf2/HO-1 Signaling Pathway of Melatonin Nanocomposite Scaffold on Promoting Diabetic Bone Defect Repair. International Journal of Nanomedicine, [PMID:38510794] [10.2147/IJN.S449290] 23. Jia Jianping, Chen Zhitao, Li Qingqing, Li Feifei, Liu Siru, Bao Guoliang. (2024) The enhancement of astaxanthin production in Phaffia rhodozyma through a synergistic melatonin treatment and zinc finger transcription factor gene overexpression. Frontiers in Microbiology, [PMID:38666259] [10.3389/fmicb.2024.1367084] 24. Xiali Guan, Gang Zhou, Yubo Fan. (2025) Enhanced sensitivity electrochemical sensor for melatonin detection using Antibody-Anchored RGO and silver nanoparticles. MICROCHEMICAL JOURNAL, [PMID:] [10.1016/j.microc.2025.113702] Calculadoras de soluciones
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