Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
Moligand™, 10mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 10 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Information
Mefenamic Acid (CI 473, CN-35355) is a competitive inhibitor ofCOX-1andCOX-2.
In vitro
In vivo
Cell Data
cell lines:PDAC(pancreatic ductal adenocarcinoma) cells
Concentrations:
Incubation Time:
Powder Purity:≥99%
| ALogP | 5.1 |
|---|
| Isómeros SMILES | CC1=C(C(=CC=C1)NC2=CC=CC=C2C(=O)O)C |
|---|---|
| WGK Alemania | 3 |
| RTECS | CB4550000 |
| Peso molecular | 241.29 |
| Reaxy-Rn | 2216243 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2216243&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Solubilidad | Solubility (25°C) In vitro DMSO: 42 mg/mL (199.78 mM); Ethanol: 42 mg/mL (199.78 mM); Water: Insoluble; |
|---|---|
| Punto de fusión (°C) | 230°C |
| 1. Xinyi Wang, Shijie Xu, Lina Jia, Yujia Yang, Yu Liu, Junbo Gong, Songgu Wu. (2019) Drug–drug salts of mefenamic acid\tolfenamic acid and piperazine to improve physicochemical properties for potential veterinary use. CRYSTENGCOMM, 21 (35): (5284-5291). [PMID:] [10.1039/C9CE00781D] |
| 2. Xinyi Wang, Yifu Chen, Junbo Gong, Jinze Hou. (2019) Aggregation-induced emission and polymorphism/shape/size-dependent emission behaviours of fenamates for potential drug evaluation. ORGANIC & BIOMOLECULAR CHEMISTRY, 17 (13): (3409-3415). [PMID:30869715] [10.1039/C9OB00338J] |
| 3. Xinyi Wang, Dejiang Zhang, Shiyuan Liu, Yifu Chen, Lina Jia, Songgu Wu. (2018) Thermodynamic Study of Solubility for Imatinib Mesylate in Nine Monosolvents and Two Binary Solvent Mixtures from 278.15 to 318.15 K. JOURNAL OF CHEMICAL AND ENGINEERING DATA, [PMID:] [10.1021/acs.jced.8b00551] |
| 4. Xue Shu-Wen, Li Jing, Xu Li. (2017) Preparation of magnetic melamine-formaldehyde resin and its application to extract nonsteroidal anti-inflammatory drugs. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 409 (12): (3103-3113). [PMID:28224244] [10.1007/s00216-017-0251-8] |
| 5. Yuqing Li, Yanhua Sun, Jian Chen, Xiaohong Zhu, Hui Li, Shen Huang, Yuwei Hu, Qi Chen, Shian Zhong. (2016) Graphene oxide as a sacrificial material for fabricating molecularly imprinted polymers via Pickering emulsion polymerization. RSC Advances, 6 (78): (74654-74661). [PMID:] [10.1039/C6RA17672K] |
| 6. Luo Zhi-yuan, Li Zhi-yong, Liu Hai-yan, Tang Min-qiong, Shi Zhi-guo. (2015) Click chemistry-based synthesis of water-dispersible hydrophobic magnetic nanoparticles for use in solid phase extraction of non-steroidal anti-inflammatory drugs. MICROCHIMICA ACTA, 182 (15): (2585-2591). [PMID:] [10.1007/s00604-015-1638-x] |
| 7. Lian Xu, Yan Xiao, Kun Yu, Hongshuo Pan, Jiayi Xu, Yiyun Guan, Mengke Wang, Xiangyu Xu, Hao Wang. (2025) Machine Learning-Assisted Chemical Tongues Based on Dual-channel Inclusion Complexes for Rapid Identification of Nonsteroidal Anti-inflammatory Drugs in Food. ACS Sensors, [PMID:39992799] [10.1021/acssensors.4c02806] |
| 8. Zhiyong Wu, Xinhao Wang, Lin Wang, Na Sun, Zihui Yang, Jianguo Zeng. (2025) Research on the metabolites and key metabolic enzymes of allocryptopine in chicken liver microsomes via stable isotope tracing technology. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS, [PMID:39805195] [10.1016/j.jpba.2025.116667] |
| 9. Xueping Quan, Bing Yan. (2023) In Situ Generated Dye@MOF/COF Heterostructure for Fluorescence Detection of Chloroquine Phosphate and Folic Acid via Different Luminescent Channels. ACS Applied Materials & Interfaces, [PMID:37972380] [10.1021/acsami.3c11298] |
| 10. Kai Ni, Bo Che, Rong Gu, Chunhong Wang, Hongyang Xu, Huiduo Li, Shiyan Cen, Mingzhi Luo, Linhong Deng. (2024) BitterDB database analysis plus cell stiffness screening identify flufenamic acid as the most potent TAS2R14-based relaxant of airway smooth muscle cells for therapeutic bronchodilation. Theranostics, [PMID:38389834] [10.7150/thno.92492] |
Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.
View Moligand™ grade guide →