Mefenamic Acid - Moligand™, 10mM in DMSO , Cyclooxygenase inhibitor, CAS No.61-68-7, Cyclooxygenase inhibitor

CAS: 61-68-7 Cat. No.: M408474 Peso molecular: 241.29 Número EC: 200-513-1
Disponible para pedir
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
Synonyms
CI 473, CN-35355 | Benzoic acid, 2-[(2,3-dimethylphenyl)amino]-
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
1ml
M408474-1ml
2

119,90US$

173,90US$
Guardar 54,00 US$ (31.05%)
Enter a quantity for the sizes you want to add.
🧪

Why this grade

Moligand™, 10mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 10 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

Information

Mefenamic Acid (CI 473, CN-35355) is a competitive inhibitor ofCOX-1andCOX-2.
In vitro


In vivo


Cell Data

cell lines:PDAC(pancreatic ductal adenocarcinoma) cells

Concentrations:

Incubation Time:

Powder Purity:≥99%

Specifications

Sinónimos
CI 473, CN-35355 | Benzoic acid, 2-[(2, 3-dimethylphenyl)amino]-
Especificaciones y pureza
Moligand™, 10mM in DMSO
Mecanismos bioquímicos y fisiológicos
Mefenamic Acid (CI 473, CN-35355) is a competitive inhibitor of COX-1 and COX-2.
Condiciones de almacenamiento de almacenamiento
Store at -80°C
Enviado en
Dry ice packs + Cold packs
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Grado
Moligand™
Tipo de acción
ACTIVATOR, CHANNEL BLOCKER, INHIBITOR
Mecanismo de acción
Cyclooxygenase inhibitor
Propiedades del producto
ALogP5.1
Nombres e identificadores
Isómeros SMILES CC1=C(C(=CC=C1)NC2=CC=CC=C2C(=O)O)C
WGK Alemania 3
RTECS CB4550000
Peso molecular 241.29
Reaxy-Rn 2216243
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2216243&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Objetivos asociados (humanos)
NAPRT Tchem Nicotinate phosphoribosyltransferase (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PTGS1 Tclin Prostaglandin G/H synthase 1 (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
PTGS2 Tclin Prostaglandin G/H synthase 2 (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
MPO Tchem Myeloperoxidase (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
AKR1C2 Tchem Aldo-keto reductase family 1 member C2 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
AKR1C3 Tchem Aldo-keto reductase family 1 member C3 (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
AKR1C1 Tchem Aldo-keto reductase family 1 member C1 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propiedades químicas y físicas
SolubilidadSolubility (25°C) In vitro DMSO: 42 mg/mL (199.78 mM); Ethanol: 42 mg/mL (199.78 mM); Water: Insoluble;
Punto de fusión (°C)230°C
Preguntas frecuentes y artículos
Citations of This Product
Referencias
1. Xinyi Wang, Shijie Xu, Lina Jia, Yujia Yang, Yu Liu, Junbo Gong, Songgu Wu.  (2019)  Drug–drug salts of mefenamic acid\tolfenamic acid and piperazine to improve physicochemical properties for potential veterinary use.  CRYSTENGCOMM,  21  (35): (5284-5291).  [PMID:] [10.1039/C9CE00781D]
2. Xinyi Wang, Yifu Chen, Junbo Gong, Jinze Hou.  (2019)  Aggregation-induced emission and polymorphism/shape/size-dependent emission behaviours of fenamates for potential drug evaluation.  ORGANIC & BIOMOLECULAR CHEMISTRY,  17  (13): (3409-3415).  [PMID:30869715] [10.1039/C9OB00338J]
3. Xinyi Wang, Dejiang Zhang, Shiyuan Liu, Yifu Chen, Lina Jia, Songgu Wu.  (2018)  Thermodynamic Study of Solubility for Imatinib Mesylate in Nine Monosolvents and Two Binary Solvent Mixtures from 278.15 to 318.15 K.  JOURNAL OF CHEMICAL AND ENGINEERING DATA,      [PMID:] [10.1021/acs.jced.8b00551]
4. Xue Shu-Wen, Li Jing, Xu Li.  (2017)  Preparation of magnetic melamine-formaldehyde resin and its application to extract nonsteroidal anti-inflammatory drugs.  ANALYTICAL AND BIOANALYTICAL CHEMISTRY,  409  (12): (3103-3113).  [PMID:28224244] [10.1007/s00216-017-0251-8]
5. Yuqing Li, Yanhua Sun, Jian Chen, Xiaohong Zhu, Hui Li, Shen Huang, Yuwei Hu, Qi Chen, Shian Zhong.  (2016)  Graphene oxide as a sacrificial material for fabricating molecularly imprinted polymers via Pickering emulsion polymerization.  RSC Advances,  (78): (74654-74661).  [PMID:] [10.1039/C6RA17672K]
6. Luo Zhi-yuan, Li Zhi-yong, Liu Hai-yan, Tang Min-qiong, Shi Zhi-guo.  (2015)  Click chemistry-based synthesis of water-dispersible hydrophobic magnetic nanoparticles for use in solid phase extraction of non-steroidal anti-inflammatory drugs.  MICROCHIMICA ACTA,  182  (15): (2585-2591).  [PMID:] [10.1007/s00604-015-1638-x]
7. Lian Xu, Yan Xiao, Kun Yu, Hongshuo Pan, Jiayi Xu, Yiyun Guan, Mengke Wang, Xiangyu Xu, Hao Wang.  (2025)  Machine Learning-Assisted Chemical Tongues Based on Dual-channel Inclusion Complexes for Rapid Identification of Nonsteroidal Anti-inflammatory Drugs in Food.  ACS Sensors,      [PMID:39992799] [10.1021/acssensors.4c02806]
8. Zhiyong Wu, Xinhao Wang, Lin Wang, Na Sun, Zihui Yang, Jianguo Zeng.  (2025)  Research on the metabolites and key metabolic enzymes of allocryptopine in chicken liver microsomes via stable isotope tracing technology.  JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,      [PMID:39805195] [10.1016/j.jpba.2025.116667]
9. Xueping Quan, Bing Yan.  (2023)  In Situ Generated Dye@MOF/COF Heterostructure for Fluorescence Detection of Chloroquine Phosphate and Folic Acid via Different Luminescent Channels.  ACS Applied Materials & Interfaces,      [PMID:37972380] [10.1021/acsami.3c11298]
10. Kai Ni, Bo Che, Rong Gu, Chunhong Wang, Hongyang Xu, Huiduo Li, Shiyan Cen, Mingzhi Luo, Linhong Deng.  (2024)  BitterDB database analysis plus cell stiffness screening identify flufenamic acid as the most potent TAS2R14-based relaxant of airway smooth muscle cells for therapeutic bronchodilation.  Theranostics,      [PMID:38389834] [10.7150/thno.92492]
Calculadoras de soluciones
Reseñas

Reseñas de cliente

Need help choosing the grade?

Our grade selection guide covers purity, stabilizer status, and application suitability for all variants in our catalog.

View Moligand™ grade guide →

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.