Memantine is effective against Alzheimer′s disease and Parkinson′s disease. It is also useful in treating epilepsy, motor neurone disease and trauma.Antagonist at the NMDA receptor. Acts as a fast, voltage-dependent, open channel NMDA receptor blocker. Us
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
This compound belongs to the class of organic compounds known as monoalkylamines. These are organic compounds containing an primary aliphatic amine group.
External Descriptors
hydrochloride
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
1.Jiawen Han, Yaru Ding, Xujuan Lv, Yuwei Zhang, Daoqing Fan. (2023) Integration of G-Quadruplex and Pyrene as a Simple and Efficient Ratiometric Fluorescent Platform That Programmed by Contrary Logic Pair for Highly Sensitive and Selective Coralyne (COR) Detection. Biosensors-Basel, 13 (4):(489). [PMID:37185564][10.3390/bios13040489]
2.Fangfang Shen, Dingqiang Lu, Xiuquan Ling, Xinxian Wang, Tongqi Liu, Tianhua Huang, Kefei He. (2016) Thermodynamic analysis and calculation of solubility of Memantine hydrochloride in ethanol plus (acetonitrile, water, ethyl acetate) binary solvent mixtures. JOURNAL OF MOLECULAR LIQUIDS, [PMID:][10.1016/j.molliq.2016.12.051]
3.Gong Chen, Panyang Gu, Wenfang Wu, Yuan Yin, Liangyu Pan, Shu Huang, Wei Lin, Meichun Deng. (2024) SETD2 deficiency in peripheral sensory neurons induces allodynia by promoting NMDA receptor expression through NFAT5 in rodent models. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES, [PMID:39476923][10.1016/j.ijbiomac.2024.136767]
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