MES sodium salt - ≥99% , CAS No.71119-23-8

CAS: 71119-23-8 Cat. No.: M105136 Peso molecular: 217.22 Beilstein Registry Number: 3765682 Número EC: 275-203-2

GRADE & PURITY ≥99%

Synonyms

MES, Sodium Salt | 4-Morpholineethanesulfonic acid, sodium salt (1:1) | MFCD00065473 | AKOS017345110 | HMS1921H03 | 4-Morpholineethanesulfonic acid, sodium salt | AKOS024457865 | Monolite GT | sodium 2-(morpholin-4-yl)ethane-1-sulfonate | sodium 2-morphol

Storage

Store at 2-8°C,Argon charged

Shipped In

Wet ice

Descripción general

MES Sodium Salt (Sodium 2-Morpholinoethanesulfonate) is a zwitterionic N-substituted aminosulfonic acid known as a Good’s buffer, active in the pH range 6-8 with a pKa of 6.10 at 25°C. With a pKa value near physiological pH, it is not absorbed through cell membranes, and it is essentially transparent to UV light. MES is used as a running buffer for resolving very small proteins (ex: 13 kDa) on bis-tris gels. Also used in cation-exchange chromatography and as a biological buffer in plant cell cultures. MES solutions can be prepared to the desired pH by titrating the free acid with sodium hydroxide.
A buffering agent used in biological and biochemical research including plant cell culture.

Specifications

Sinónimos

MES, Sodium Salt | 4-Morpholineethanesulfonic acid, sodium salt (1:1) | MFCD00065473 | AKOS017345110 | HMS1921H03 | 4-Morpholineethanesulfonic acid, sodium salt | AKOS024457865 | Monolite GT | sodium 2-(morpholin-4-yl)ethane-1-sulfonate | sodium 2-morphol

Especificaciones y pureza

≥99%

Mecanismos bioquímicos y fisiológicos

Buffering agent. Working pH range in aqueous solution: 5.5 - 6.7. Used in cell culture, eletrophoresis and capillary eletrochromatography.

Condiciones de almacenamiento de almacenamiento

Store at 2-8°C, Argon charged

Enviado en

Wet ice

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Pureza

≥99%

Nombres e identificadores

• Sonrisas canónicas: C1COCCN1CCS(=O)(=O)[O-].[Na+]
• IUPAC Name: sodium;2-morpholin-4-ylethanesulfonate
• InChIKey: IRHWMYKYLWNHTL-UHFFFAOYSA-M
• INCHI: 1S/C6H13NO4S.Na/c8-12(9,10)6-3-7-1-4-11-5-2-7;/h1-6H2,(H,8,9,10);/q;+1/p-1
• Isómeros SMILES: C1COCCN1CCS(=O)(=O)[O-].[Na+]
• WGK Alemania: 1
• Peso molecular: 217.22
• Beilstein: 3765682
• Reaxy-Rn: 3765682
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3765682&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Clase Oxazinanes
      • Subclass Morpholines

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Clase: Oxazinanes
• Subclass: Morpholines
• Intermediate Tree Nodes: Not available
• Direct Parent: Morpholines
• Alternative Parents: Sulfonyls Organosulfonic acids Alkanesulfonic acids Trialkylamines Oxacyclic compounds Dialkyl ethers Azacyclic compounds Organopnictogen compounds Organic zwitterions Organic sodium salts Organic oxides Hydrocarbon derivatives
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: Morpholine - Organic sulfonic acid or derivatives - Organosulfonic acid or derivatives - Organosulfonic acid - Sulfonyl - Alkanesulfonic acid - Tertiary amine - Tertiary aliphatic amine - Dialkyl ether - Ether - Oxacycle - Azacycle - Organic alkali metal salt - Hydrocarbon derivative - Organic oxide - Organopnictogen compound - Organic oxygen compound - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Amine - Organic nitrogen compound - Organic zwitterion - Organic salt - Organic sodium salt - Aliphatic heteromonocyclic compound
• Descripción: This compound belongs to the class of organic compounds known as morpholines. These are organic compounds containing a morpholine moiety, which consists of a six-member aliphatic saturated ring with the formula C4H9NO, where the oxygen and nitrogen atoms lie at positions 1 and 4, respectively.
• External Descriptors: organic sodium salt

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Solubilidad: Solvent:water, Max Conc. mg/mL: 21.72, Max Conc. mM: 100
• Sensibilidad: Hygroscopic;heat sensitive
• Peso molecular: 217.220 g/mol
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 3
• Exact Mass: 217.038 Da
• Monoisotopic Mass: 217.038 Da
• Topological Polar Surface Area: 78.100 Ų
• Heavy Atom Count: 13
• Formal Charge: 0
• Complexity: 219.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3

Referencias

1. Sheng Chang, Qiang Yang, Jiahuan Liu, Li Yin, Jihong Han, Lanlan Zong, Xiaohui Pu.  (2024)  The Increased Dissolution and Oral Absorption of Itraconazole by Nanocrystals with an Endogenous Small-Molecule Surfactant as a Stabilizer.  MOLECULES,  29  (8): (1769).  [PMID:38675589] [10.3390/molecules29081769]

2. Fei Pan, Mu Yang, Shichuan Zhang, Wei Zhang, Yungchang Chen, Huangming Hong, Yuke Tian, Reqin Li, Huawei Weng, Zegeng Chen, Meiting Chen, Huageng Huang, Xiaoqian Li, Tongtong Feng.  (2025)  Tumor microenvironment-responsive nanoparticles composed of hyaluronic acid and stearic acid for the treatment of lung metastasis in triple-negative breast cancer.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:41391799] [10.1016/j.ijbiomac.2025.149492]