Metil-β-ciclodextrina - media Mn 1310 , CAS No.128446-36-6

CAS: 128446-36-6 Cat. No.: M102038 Número EC: 603-270-3 PubChem CID: 51051622

GRADE & PURITY average Mn 1310

Synonyms

MEBCD | Methyl-β-CD | Methyl-beta-cyclodextrin

Storage

Temperatura ambiente

Shipped In

Normal

Descripción general

la metil-β-ciclodextrina(MβCD) es un compuesto macrocíclico que puede formar complejos de inclusión con diversas moléculas huéspedes. Presenta mayor solubilidad en soluciones acuosas y mayor poder solubilizante y complejante que la β-ciclodextrina madre. MβCD puede utilizarse para mejorar la actividad enzimática y la enantioselectividad de la enzima subtilizante en disolventes orgánicos.

Aplicación:
La metil-β-ciclodextrina es un agente eliminador de colesterol que se utiliza principalmente para la disrupción de balsas lipídicas[4]. También se puede utilizar para la eliminación de detergentes de la mezcla ternaria proteína-lípido-detergente para producir cristales de proteínas de membrana 2D debido a su alta solubilidad y afinidad por los detergentes generalmente utilizados en la química de proteínas de membrana.
La metil-β-ciclodextrina puede utilizarse como:
Un aditivo tampón para la separación eficaz de aminofosfolípidos mediante cromatografía capilar electrocinética micelar modificada (MEKC) acoplada con detección por fluorescencia inducida por láser.
Un aditivo de fase móvil para el análisis de mezclas de R,S-naproxeno en formulaciones de comprimidos comerciales mediante cromatografía convencional y nano-líquida (nano-LC).
Un estándar analítico para la determinación del analito en muestras biológicas mediante cromatografía líquida de alta resolución (HPLC).
Un selector quiral para la resolución de enantiómeros de repaglinida en formulaciones farmacéuticas mediante electroforesis capilar.

Specifications

Sinónimos

MEBCD | Methyl-β-CD | Methyl-beta-cyclodextrin

Especificaciones y pureza

media Mn 1310

Condiciones de almacenamiento de almacenamiento

Temperatura ambiente

Enviado en

Normal

Nombres e identificadores

• Pubchem Sid: 488201479
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488201479
• Isómeros SMILES: CO[C@H]1[C@@H]([C@H]2[C@H](O[C@@H]1O[C@@H]3[C@H](O[C@@H]([C@H]([C@@H]3OC)OC)O[C@@H]4[C@H](O[C@@H]([C@H]([C@@H]4OC)OC)O[C@@H]5[C@H](O[C@@H]([C@H]([C@@H]5OC)OC)O[C@@H]6[C@H](O[C@@H]([C@H]([C@@H]6OC)OC)O[C@@H]7[C@H](O[C@@H]([C@H]([C@@H]7OC)OC)O[C@@H]8[C@H](O[C@H](O2)[C@H]([C@@H]8O)OC)CO)CO)CO)CO)CO)CO)CO)O
• WGK Alemania: 3
• PubChem CID: 51051622

Propiedades químicas y físicas

• Solubilidad: Soluble in water
• Rotación específica [α]: [α]25/D +159°, c = 1 in H2O
• Punto de inflamación (°F): 368.6 °F
• Punto de inflamación (°C): 63℃
• Punto de fusión (°C): 180-182 °C
• Peso molecular: 1303.300 g/mol
• XLogP3: -8.600
• Hydrogen Bond Donor Count: 9
• Hydrogen Bond Acceptor Count: 35
• Rotatable Bond Count: 19
• Exact Mass: 1302.56 Da
• Monoisotopic Mass: 1302.56 Da
• Topological Polar Surface Area: 422.000 Ų
• Heavy Atom Count: 89
• Formal Charge: 0
• Complexity: 2050.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 35
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

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60. Shuang E, Quan-Xing Mao, Xiao-Li Yuan, Xiao-Lei Kong, Xu-Wei Chen, Jian-Hua Wang.  (2018)  Targeted imaging of the lysosome and endoplasmic reticulum and their pH monitoring with surface regulated carbon dots.  Nanoscale,  10  (26): (12788-12796).  [PMID:29947397] [10.1039/C8NR03453B]

61. Yumeng Zhang, Lin Chen, Yuanqi Lv, Shuangxi Wang, Zhiyao Suo, Xingguang Cheng, Xinglian Xu, Guanghong Zhou, Zhixi Li, Xianchao Feng.  (2018)  Inhibition of interaction between epigallocatechin-3-gallate and myofibrillar protein by cyclodextrin derivatives improves gel quality under oxidative stress.  FOOD RESEARCH INTERNATIONAL,      [PMID:29735104] [10.1016/j.foodres.2018.03.008]

62. Hu Gaowei, Zheng Wenlv, Li Ao, Mu Yaru, Shi Mingyu, Li Tuofan, Zou Haitao, Shao Hongxia, Qin Aijian, Ye Jianqiang.  (2018)  A novel CAV derived cell-penetrating peptide efficiently delivers exogenous molecules through caveolae-mediated endocytosis.  VETERINARY RESEARCH,  49  (1): (1-9).  [PMID:29439726] [10.1186/s13567-018-0513-2]

63. Yunti Zhang, Qimin Jiang, Bo Bi, Luming Xu, Jia Liu, Renxi Zhuo, Xulin Jiang.  (2018)  A bioreducible supramolecular nanoparticle gene delivery system based on cyclodextrin-conjugated polyaspartamide and adamantyl-terminated polyethylenimine.  Journal of Materials Chemistry B,  6  (5): (797-808).  [PMID:32254267] [10.1039/C7TB02170D]

64. Guang-Yu Pan, Hao-Ran Jia, Ya-Xuan Zhu, Fu-Gen Wu.  (2017)  Turning double hydrophilic into amphiphilic: IR825-conjugated polymeric nanomicelles for near-infrared fluorescence imaging-guided photothermal cancer therapy.  Nanoscale,  10  (4): (2115-2127).  [PMID:29326993] [10.1039/C7NR07495F]

65. Ying Li, Meng Wang, Bu-Wei Huang, Yuan Ping, Jian You, Jian-Qing Gao.  (2017)  Transcriptome-wide elucidation of liposomal formulations for anticancer drug delivery.  International Journal of Nanomedicine,      [PMID:29238192] [10.2147/IJN.S148975]

66. Sun Xin-Yuan, Gan Qiong-Zhi, Ouyang Jian-Ming.  (2017)  Size-dependent cellular uptake mechanism and cytotoxicity toward calcium oxalate on Vero cells.  Scientific Reports,  7  (1): (1-12).  [PMID:28150811] [10.1038/srep41949]

67. Huipeng Li, Nida El Islem Guissi, Zhigui Su, Qineng Ping, Minjie Sun.  (2016)  Effects of surface hydrophilic properties of PEG-based mucus-penetrating nanostructured lipid carriers on oral drug delivery.  RSC Advances,  6  (87): (84164-84176).  [PMID:] [10.1039/C6RA18724B]

68. Shanshan Wang, Zhangkun Liu, Yuxiu Zou, Xiaofang Lai, Ding Ding, Long Chen, Liqin Zhang, Yuan Wu, Zhuo Chen, Weihong Tan.  (2016)  Elucidating the cellular uptake mechanism of aptamer-functionalized graphene-isolated-Au-nanocrystals with dual-modal imaging.  ANALYST,  141  (11): (3337-3342).  [PMID:27111129] [10.1039/C6AN00483K]

69. Liu Di, Guo Hua, Zheng Wenyun, Zhang Na, Wang Tianwen, Wang Ping, Ma Xingyuan.  (2016)  Discovery of the cell-penetrating function of A2 domain derived from LTA subunit of Escherichia coli heat-labile enterotoxin.  APPLIED MICROBIOLOGY AND BIOTECHNOLOGY,  100  (11): (5079-5088).  [PMID:26960316] [10.1007/s00253-016-7423-x]

70. Junhui Pan, Langhong Wang, Guowen Zhang, Deming Gong.  (2015)  Intercalation of 2-butyl-4-methylphenol to G–C rich region of DNA and the role of hydroxypropyl-β-cyclodextrin.  JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY,      [PMID:26245840] [10.1016/j.jphotobiol.2015.07.021]

71. Hua He, Yugang Bai, Jinhui Wang, Qiurong Deng, Lipeng Zhu, Fenghua Meng, Zhiyuan Zhong, Lichen Yin.  (2015)  Reversibly Cross-Linked Polyplexes Enable Cancer-Targeted Gene Delivery via Self-Promoted DNA Release and Self-Diminished Toxicity.  BIOMACROMOLECULES,      [PMID:25756930] [10.1021/acs.biomac.5b00180]

72. Junwei Lv, Xianqing Yang, Haixia Ma, Xiao Hu, Ya Wei, Wanjun Zhou, Laihao Li.  (2015)  The oxidative stability of microalgae oil (Schizochytrium aggregatum) and its antioxidant activity after simulated gastrointestinal digestion: Relationship with constituents.  EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY,  117  (12): (1928-1939).  [PMID:] [10.1002/ejlt.201400588]

73. Ming-Zhen Zhang, Yong Yu, Rong-Na Yu, Min Wan, Rong-Ying Zhang, Yuan-Di Zhao.  (2013)  Tracking the Down-Regulation of Folate Receptor-α in Cancer Cells through Target Specific Delivery of Quantum Dots Coupled with Antisense Oligonucleotide and Targeted Peptide.  Small,  9  (24): (4183-4193).  [PMID:23828664] [10.1002/smll.201300994]

74. Cuihong Yang, Dongxia Li, Zheng Liu, Ge Hong, Jun Zhang, Deling Kong, Zhimou Yang.  (2011)  Responsive Small Molecular Hydrogels Based on Adamantane–Peptides for Cell Culture.  JOURNAL OF PHYSICAL CHEMISTRY B,      [PMID:22111956] [10.1021/jp209441r]

75. Yilin Li, Xin Duan, Lihong Jing, Chunhui Yang, Ruirui Qiao, Mingyuan Gao.  (2010)  Quantum dot-antisense oligonucleotide conjugates for multifunctional gene transfection, mRNA regulation, and tracking of biological processes.  BIOMATERIALS,      [PMID:21145105] [10.1016/j.biomaterials.2010.11.024]

76. Mengxin Zhang, Yingyu Zhang, Qionglin Wang, Kangbo Liu, Lifeng Li, Zhidan Yu, Ligong Hou, Xianwei Zhang, Huan Zhao, Weyland Cheng, Wancun Zhang.  (2024)  An APE1 gated signal amplified biosensor driven by catalytic hairpin assembly for the specific imaging of microRNA in situ.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:38307426] [10.1016/j.ijbiomac.2024.129902]

77. Mengxin Zhang, Yingyu Zhang, Xianwei Zhang, Kangbo Liu, Lifeng Li, Zhidan Yu, Jingya Yuan, Wancun Zhang.  (2024)  An Enzymatically Activated and Catalytic Hairpin Assembly-Driven Intelligent AND-Gated DNA Network for Tumor Molecular Imaging.  ANALYTICAL CHEMISTRY,      [PMID:38836421] [10.1021/acs.analchem.4c02076]

78. Mengxin Zhang, Yingyu Zhang, Xianwei Zhang, Qionglin Wang, Kangbo Liu, Muchun Yu, Lifeng Li, Zhidan Yu, Huan Zhao, Weyland Cheng, Wancun Zhang.  (2024)  An enzymatically activated self-powered and self-recycled strategy for in situ tumor cell-specific molecular imaging.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2024.151226]

79. Mingshan Chen, Zhiyu Hu, Haoyuan Zheng, Jiesheng Wang, Xiaowen Xu.  (2024)  Antimicrobial polysaccharide hydrogels embedded with methyl-β-cyclodextrin/thyme oil inclusion complexes for exceptional mechanical performance and chilled chicken breast preservation.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:38615861] [10.1016/j.ijbiomac.2024.131586]

80. Xiuhua Pan, Jie Yang, Ruixin Kang, Jun Zhang, Zongwei Hu, Ning Yang, Zengyi Liu, Zengguang Jia, Xiawei Zhou, Qi Shen.  (2024)  Biomimetic bacteria-derived nanoclusters enhance ferroptosis cancer immunotherapy through synergistic CRISPR-photothermo modulation.  Nano Today,      [PMID:] [10.1016/j.nantod.2024.102213]

81. Gege Zeng, Zepeng He, Haihong Yang, Zhan Gao, Xueer Ge, Lixin Liu, Zhijia Liu, Yongming Chen.  (2024)  Cationic Lipid Pairs Enhance Liver-to-Lung Tropism of Lipid Nanoparticles for In Vivo mRNA Delivery.  ACS Applied Materials & Interfaces,      [PMID:38717294] [10.1021/acsami.4c02415]

82. Xiaotong Yu, Mengying Xia, Yuanhong Li, Geyun Chen, Chenhao Yu, Qianming Chen, Qiang Peng.  (2024)  Cationic liposomes as a drug-free system for efficient anticancer therapy by intracytoplasmic delivery of sodium bicarbonate.  COLLOIDS AND SURFACES B-BIOINTERFACES,      [PMID:38795588] [10.1016/j.colsurfb.2024.113984]

83. Chen Lu, Jiayue Chen, Shengsheng Zhang, Yaru Tian, Xinyu Ying, Dan Zhang, Zhidan Luo, Xinxin Si, Ming Li.  (2025)  Development of a vitrified CRISPR/Cas12b-based assay for rapid genotyping of SLCO1B1 SNPs without DNA amplification.  Analytical Methods,      [PMID:39936934] [10.1039/D4AY02015D]

84. Dan Li, Gaoyang Yi, Guifang Cao, Adam C. Midgley, Yongli Yang, Dan Yang, Wenguang Liu, Yujuan He, Xiaolin Yao, Guoliang Li.  (2025)  Dual-Carriers of Tartary Buckwheat-Derived Exosome-Like Nanovesicles Synergistically Regulate Glucose Metabolism in the Intestine-Liver Axis.  Small,      [PMID:40079102] [10.1002/smll.202410124]

85. Chang Liu, Chao He, Qing Zeng, Dengqun Liao, Xianen Li.  (2024)  Encapsulated urolithin B–methyl-β-cyclodextrin inclusion complex: synthesis, characterization, in vivo pharmacokinetics with hypolipidemic effect.  Carbohydrate Polymer Technologies and Applications,      [PMID:] [10.1016/j.carpta.2024.100636]

86. Yanzhi Xing, Jiaxin Li, Han Leng, Yanfeng Zhang, Shuang E, Jianhua Wang, Xuwei Chen.  (2024)  From cell membrane to endoplasmic reticulum: Tunable lipid membrane imaging by regulating the lipophilicity and internalization of carbon dots.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2024.152068]

87. Wenrui Hu, Hang Ao, Ziyi Lv, Wencheng Xiao, Wei Li, Jianping Lei, Jie Wu, Huangxian Ju.  (2024)  Glow-type luminol chemiluminescence based on a supramolecular enhancer of cyclodextrin.  ANALYTICA CHIMICA ACTA,      [PMID:39266198] [10.1016/j.aca.2024.343182]

88. Jie Meng, Wei Wei, Shuang Xie, Junwu Wei, Zhanlin Zhang, Pan Ran, Xiaohong Li.  (2024)  Hollow and heterojunction-structured Janus nanomotors for pyroelectrodynamic and nanozyme-catalyzed tumor therapy.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2024.157763]

89. Wubuli Abudukahaer, Chai Junwei, Liu Haoqiang, Nijat Dilaram, Li Jianmin, Xia Guoyu, Cao Qi, Zhang Saidan, Huang Weidong, Aipire Adila, Li Jinyao.  (2024)  In vivo pharmacokinetics of Glycyrrhiza uralensis polysaccharides.  Frontiers in Pharmacology,      [PMID:39101144] [10.3389/fphar.2024.1431221]

90. Pu Zheng, Xinru Chen, Chunyang Zhao, Jialong Wang, Jianhong Zhang, Xiong Hu, Wenchao Geng, Qianqian Zhao.  (2024)  Integrating strategy to investigate the formation and stabilization mechanisms of Curcumin-Cyclodextrin inclusion complexes: Experimental characterizations and multi-scale computational simulations.  FOOD HYDROCOLLOIDS,      [PMID:] [10.1016/j.foodhyd.2024.110679]

91. Yadan Zhang, Xiaoyu Zhang, Tianhan Kai, Lin Zhang, Anping Li.  (2024)  Lycium ruthenicum Murray derived exosome-like nanovesicles inhibit Aβ-induced apoptosis in PC12 cells via MAPK and PI3K/AKT signaling pathways.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:39089544] [10.1016/j.ijbiomac.2024.134309]

92. Dan Yuan, Zhicheng Niu, Wenyu Zheng, Qiangzhong Zhao, Feibai Zhou, Mouming Zhao.  (2024)  Mind the Particle Rigidity: Blooms the Bioavailability via Rapidly Crossing the Mucus Layer and Alters the Intracellular Fate of Curcumin.  ACS Nano,      [PMID:39297569] [10.1021/acsnano.4c09838]

93. Meng Ding, Yuan Zhu, Xiaoting Xu, Hui He, Tianyu Jiang, Xiaochuan Mo, Zhuting Wang, Wenfeng Yu, Hailong Ou.  (2024)  Naringenin Inhibits Acid Sphingomyelinase-Mediated Membrane Raft Clustering to Reduce NADPH Oxidase Activation and Vascular Inflammation.  JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY,      [PMID:38516841] [10.1021/acs.jafc.3c07874]

94. Yang Chen, Wenzhe Xu, Hao Jin, Mengsi Zhang, Shuwei Liu, Yi Liu, Hao Zhang.  (2024)  Nutritional Glutamine-Modified Iron-Delivery System with Enhanced Endocytosis for Ferroptosis Therapy of Pancreatic Tumors.  ACS Nano,      [PMID:39512234] [10.1021/acsnano.4c08083]

95. Xia Lei, Jie Meng, Tianyu Gao, Mengxue Zhang, Zhanlin Zhang, Shuang Xie, Yupeng Su, Xiaohong Li.  (2025)  pH-Responsive photothermal effect and heterojunction formation for tumor-specific pyroelectrodynamic and nanozyme-catalyzed starvation therapy.  Acta Biomaterialia,      [PMID:40113022] [10.1016/j.actbio.2025.03.031]

96. Dan Yang, Yuqi Feng, Ying Yuan, Linxuan Zhang, Yao Zhou, Adam C. Midgley, Yanrong Wang, Ning Liu, Guoliang Li, Xiaolin Yao, Dechun Liu.  (2024)  Protein Coronas Derived from Mucus Act as Both Spear and Shield to Regulate Transferrin Functionalized Nanoparticle Transcellular Transport in Enterocytes.  ACS Nano,      [PMID:38417159] [10.1021/acsnano.3c11315]

97. Xiuhua Pan, Feiyang Liu, Ruixin Kang, Zongwei Hu, Yueru Pang, Ziqi Shen, Xiawei Zhou, Jun Zhang, Qi Shen.  (2024)  Self-Adjuvanting Bacteria Hydrogel for SHP1 Checkpoint Inhibition in Tumor-Draining Lymph Nodes to Enhance Cancer Immunotherapy.  ADVANCED FUNCTIONAL MATERIALS,      [PMID:] [10.1002/adfm.202409736]

98. Tingting Wang, Wengui Lu, Zhifei Cheng, Luyao Wang, Zhenzhen Jiang, Yike Yue, Pengyu Jiang, Zehua Xia, Lei He, Fengying Wang, Limin Wu, Qi Wang, Hui Han.  (2025)  Oral Engineered Extracellular Vesicles Based on Ion Exchange Strategy for Multipronged Management of Wilson's Disease Complicated with Reproductive Dysfunction Therapy.  Advanced Science,      [PMID:40673828] [10.1002/advs.202501689]

99. Wengui Lu, Chuan Zhang, Yaru Zhang, Ru Xiao, Chaoqi Wei, Fan Zhang, Zhenbao Li, Hewan Xia, Mimi Wan, Zhifei Cheng, Qi Wang.  (2025)  A programmed Ca2+ nanomodulator by dynamically regulating autophagy and neuroinflammation for Parkinson's disease therapy.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.166324]

100. Caifeng Deng, Liukang Yu, Xuan Zhao, Yuxiao Chen, Jiabin Mei, Jie Wei, Xiaoyuan Chen, Guanghua Lei, Chao Zeng.  (2025)  Genetically engineered chondrocyte-mimetic nanoplatform attenuates osteoarthritis by blocking IL-1β and restoring sirtuin-3.  Science Advances,  11  (30):   [PMID:40712009] [10.1126/sciadv.adv4238]

101. Weixia Qin, Junjie Cui, Usama, Yan Li, Rui Liu, Zhaohua Miao, Zhengbao Zha, Lei Jiang, Ming Cao, Mina Ibrahim Tadros, Antonio Claudio Tedesco, Zijian Li, Hong Bi.  (2025)  Lysosomal-Targeting and Light/Ultrasound Sensitive Carbon Dots for Combined Photodynamic and Sonodynamic Therapies of Breast Tumor.  Advanced Healthcare Materials,      [PMID:40734306] [10.1002/adhm.202502873]

102. Jiayu Li, Yanchao Wang, Zihao Zhu, Yaoguang Chang, Changhu Xue.  (2025)  Identification and mechanism exploration of novel umami peptides from oysters with an integrated pipeline.  FOOD CHEMISTRY,      [PMID:40845501] [10.1016/j.foodchem.2025.145909]

103. Wen-Xuan Zhang, Jian-Feng Zhou, Hai-Xia Xu, Wen-Jun Wang, Ji-Guang Chen, Qing-Feng Zhang.  (2025)  Enhanced solubility, stability, and bioavailability of astilbin via inclusion complexes formation with methyl-β-cyclodextrin.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,      [PMID:] [10.1016/j.colsurfa.2025.138088]

104. Hongdong Song, Yaqiong Chen, Ruihan Huang, Xiao Guan.  (2025)  Propanoic acid-functionalized chitosan decorated liposomes for enhanced oral delivery and hypoglycemic effect of insulin.  COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,      [PMID:] [10.1016/j.colsurfa.2025.138184]

105. Jie Meng, Shuang Xie, Zhanlin Zhang, Pan Ran, Xia Lei, Long He, Xiaohong Li.  (2025)  pH-triggered Schottky heterojunctions for NIR-II-activated and tumor-specific pyroelectrodynamic and photothermal therapy.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,      [PMID:40915294] [10.1016/j.jcis.2025.138919]

106. Yujing Lu, Yicheng Guo, Lina Wang, Yoshimasa Nakamura, Hang Qi.  (2025)  Royal jelly exosome-based nanocarriers enhance the stability and bioactivity of polyphenols from Ascophyllum nodosum for melanin regulatio.  FOOD RESEARCH INTERNATIONAL,      [PMID:41185370] [10.1016/j.foodres.2025.117495]

107. Caifeng Deng, Yongbing Xiao, Xuan Zhao, Hui Li, Yuxiao Chen, Kelong Ai, Ting Jiang, Jie Wei, Xiaoyuan Chen, Guanghua Lei, Chao Zeng.  (2025)  Sequential Targeting Chondroitin Sulfate-Bilirubin Nanomedicine Attenuates Osteoarthritis via Reprogramming Lipid Metabolism in M1 Macrophages.  Advanced Science,      [PMID:39792653] [10.1002/advs.202411911]

108. Jiachun Wang, Juntao Hu, Wantong Jiang, Dongwei Zhu, Yinuo Yin, Yu Qin, Ao Song, Yibing Huang, Quan Luo.  (2025)  Mechanistic insights into redox-protonation coupled fluorescence switching in peptide-mediated gold nanoclusters for precision tumor imaging and resection.  JOURNAL OF COLLOID AND INTERFACE SCIENCE,      [PMID:40749287] [10.1016/j.jcis.2025.138582]

109. Su Minhui, Liu Yuan, Lin Hongxin, Wang Xiaoxing, Ying Danxia, Zhang Lizhuan, Yang Cai, Jiang Mengyuan, Xu Lujuan, Wang Xie, Sun Yang, Xu Haiyan, Zhang Ziwen, Wang Xiaojia, Fu Ting, Xie Sitao, He Jiaxuan, Liu Xiangsheng, Tan Weihong.  (2025)  An aptamer-drug conjugate for promising cancer therapy with comprehensive evaluation from rodents to non-human primates.  Signal Transduction and Targeted Therapy,  10  (1): (1-17).  [PMID:40987771] [10.1038/s41392-025-02399-1]

110. Minghui Hu, Yingyu Zhang, Jie Zhang, Xianwei Zhang, Mengxin Zhang, Kangbo Liu, Lifeng Li, Zhidan Yu, Fei Zhang, Wancun Zhang.  (2025)  Double Self-Amplified Programmable Allosteric DNA Nanomachine for Enzymatically Triggered Spatially Controllable Molecular Imaging.  ADVANCED FUNCTIONAL MATERIALS,      [PMID:] [10.1002/adfm.202501940]

111. Zhang Jianming, Teng Chao, Li Caolong, He Wei.  (2020)  Deliver Anti-inflammatory Drug Baicalein to Macrophages by Using a Crystallization Strategy.  Frontiers in Chemistry,      [PMID:33062636] [10.3389/fchem.2020.00787]

112. Wang Hong-ling, Si Xue-jing, Wu Tun-hua, Wang Ping.  (2020)  New Enhanced Method for Determination of Trace Sulfamethodxazole Based on the Fluorescence Behaviors of Cyclodextrins in Water Solutions.  JOURNAL OF FLUORESCENCE,  30  (5): (1105-1112).  [PMID:32638148] [10.1007/s10895-020-02582-3]

113. Kambere Amerigos Daddy J.C., Minglei Chen, Faisal Raza, Yanyu Xiao, Zhigui Su, Qineng Ping.  (2020)  Co-Encapsulation of Mitoxantrone and β-Elemene in Solid Lipid Nanoparticles to Overcome Multidrug Resistance in Leukemia.  Pharmaceutics,  12  (2): (191).  [PMID:32102214] [10.3390/pharmaceutics12020191]

114. Jinyan Gu, Mouming Zhao, Lijun You, Lianzhu Lin.  (2025)  Demonstration of the effective intestinal immunity activity of a high branched rhamnogalacturonan-I type pectin polysaccharide from wolfberry via exploration its interaction and mechanism with mechanical barrier.  CARBOHYDRATE POLYMERS,      [PMID:40409830] [10.1016/j.carbpol.2025.123698]

115. Zhu Lijun, Tang Zhaohui, Jiang Wen, Dong Yuwen, Li Xiaofei, Huang Kai, Wu Tiancong, Xu Lingyan, Guo Wenjie, Gu Yanhong.  (2025)  Cholesterol biosynthesis induced by radiotherapy inhibits cGAS–STING activation and contributes to colorectal cancer treatment resistance.  EXPERIMENTAL AND MOLECULAR MEDICINE,      [PMID:40355720] [10.1038/s12276-025-01457-6]

116. Wancun Zhang, Zhenzhen Tian, Pin Zhang, Lifeng Li, Zhidan Yu, Meng Sun, Kangbo Liu, Ligong Hou, Jie Zhang, Mengxin Zhang, Xianwei Zhang.  (2025)  In vivo molecular imaging of drug resistance in neuroblastoma using APE1 cyclically cleaved and miR-514a self-recycled programmable allosteric DNA nanomachine.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.164581]

117. Shengnan Li, Wei Lv, Jiangna Xu, Jiaqing Yin, Yuqin Chen, Linfeng Liu, Xiang Cao, Wenjing Li, Zhen Li, Hua Chen, Hongliang Xin.  (2025)  Artificial mesenchymal stem cell extracellular vesicles enhanced ischemic stroke treatment through targeted remodeling brain microvascular endothelial cells.  Acta Pharmaceutica Sinica B,      [PMID:40893673] [10.1016/j.apsb.2025.06.009]

118. Qiu Qiujing, Yan Xiaoyuan, Zhang Zeying, Zhang Xiyue, Ma Jiawei, Gao Wenqing, An Na, Qiu Lihong, Guo Jiajie.  (2025)  Porphyromonas gingivalis extracellular vesicles exacerbated osteoporosis by disrupting osteoblast mitochondrial dynamics and inhibiting Cpt2-regulated fatty acid oxidation.  JOURNAL OF NANOBIOTECHNOLOGY,  23  (1): (1-24).  [PMID:41074134] [10.1186/s12951-025-03717-z]

119. Yuai Li, Yunting Zhang, Jingwen Wang, Yujie Che, Tao Gong, Zhirong Zhang, Renhe Liu, Yao Fu.  (2025)  Modular Nanoassemblies Mimicking p62 Aggregates for Targeted Organelle Sequestration and Degradation against Breast Cancer.  ACS Nano,      [PMID:41063366] [10.1021/acsnano.5c10801]

120. Min Jiang, Chao Hong, Wenkui Zou, Zheng Ye, Kexu Gu, Yaning Ren, MingFang Li, Don Green, Tong Zhang, Yue Ding.  (2025)  Membrane Cholesterol-Dependent Dual VEGFR2/FGFR1 Inhibition by Ginsenoside Rg3 to Overcome Gefitinib Resistance in NSCLC.  PHYTOMEDICINE,      [PMID:41192258] [10.1016/j.phymed.2025.157421]

121. Zheng Ye, Chao Hong, Min Jiang, Wenkui Zou, Yaning Ren, Mingfang Li, Xinyue Xue, Xiaoting Xie, Tong Zhang, Yue Ding.  (2025)  Polyphyllin H Reverses Paclitaxel Resistance in Breast Cancer by Binding Membrane Cholesterol to Inhibit Both ABCB1 and ABCC3.  Pharmaceuticals,  18  (11): (1699).  [PMID:41304944] [10.3390/ph18111699]

122. Zhong Shao, Ke Li, Hao Guo, Yangyang Cheng, Shiyong Zhang.  (2025)  An oral H2S nanotherapeutics for hypertensive chronic kidney disease via synergistic antihypertensive and renoprotective activities.  JOURNAL OF CONTROLLED RELEASE,      [PMID:41260269] [10.1016/j.jconrel.2025.114419]

123. Jiaxuan Li, Yu Li, Xunyu Song, Yuxiao Wang, Yinxu Zhang, Xinghua Gao, Mingqian Tan, Wentao Su.  (2025)  Ulva lactuca Extracellular Vesicles Protect Against High-Fat Diet-Induced Intestinal Damage via Nrf2/Keap1/HO-1 Activation.  Food & Function,      [PMID:41355512] [10.1039/D5FO03126E]

124. Hao Li, Xiaowei Xie, Yu Zhang, Xiaopeng Han, Ting Shi, Jiayin Li, Wanyu Chen, Qin Wei, Hong Pan, Shuxian Xu, Qiuyu Chen, Lifang Yin, Chao Qin.  (2025)  MOF-Engineered Platelet-Mimicking Nanocarrier-Encapsulated Cascade Enzymes for ROS Scavenging and Anti-Inflammation in Cerebral Ischemia–Reperfusion Injury.  Pharmaceutics,  17  (11): (1478).  [PMID:41304816] [10.3390/pharmaceutics17111478]

125. Yushuang Wei, Haibo Chen, Rong Xu, Zhenyu Zhang, Xiangyang Li, Cheng Xu, Hongbo Pang, Kai Yang, Bing Yuan.  (2025)  Shape-Dependent Entropic Forces Govern Synergistic Bystander Nanoparticle Uptake.  ACS Nano,      [PMID:41431204] [10.1021/acsnano.5c13968]

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