α-methyl-DL-tyrosine methyl ester hydrochloride - Moligand™,≥95% , CAS No.7361-31-1

CAS: 7361-31-1 Cat. No.: M769846 Peso molecular: 245.70 Número EC: 230-900-0

GRADE & PURITY Moligand™, ≥95%

Synonyms

α-Methyltyrosine methyl ester hydrochloride, Tyrosine, alpha-methyl-, methyl ester, hydrochloride | Alpha-methyl-dl-tyrosine methyl ester hydrochloride | Methyl 2-amino-3-(4-hydroxyphenyl)-2-methylpropanoate hydrochloride

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Descripción general

α-Methyltyrosine methyl ester hydrochloride is an active and competitive tyrosine hydroxylase inhibitor. α-Methyltyrosine methyl ester hydrochloride can inhibit the conversion of tyrosine to dopamine. α-Methyltyrosine methyl ester hydrochloride causes kidney damage and urethral calculi in rats. α-Methyltyrosine methyl ester hydrochloride can be used as a tool for sympathetic nervous system research.

Specifications

Sinónimos

α-Methyltyrosine methyl ester hydrochloride, Tyrosine, alpha-methyl-, methyl ester, hydrochloride | Alpha-methyl-dl-tyrosine methyl ester hydrochloride | Methyl 2-amino-3-(4-hydroxyphenyl)-2-methylpropanoate hydrochloride

Especificaciones y pureza

Moligand™, ≥95%

Mecanismos bioquímicos y fisiológicos

α-Methyl-DL-tyrosine (α-MT) prevents hyperactivity, sniffing-licking-gnawing syndrome, anorexia and ameliorates certain effects of amphetamine. It inhibits dopamine production and prevents apoptosis stimulated by mutant α-synuclein. Tyrosine hydroxylase

Condiciones de almacenamiento de almacenamiento

Store at -20°C, Argon charged

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Grado

Moligand™

Pureza

≥95%

Nombres e identificadores

• Sonrisas canónicas: CC(CC1=CC=C(C=C1)O)(C(=O)OC)N.Cl
• IUPAC Name: methyl 2-amino-3-(4-hydroxyphenyl)-2-methylpropanoate;hydrochloride
• InChIKey: OOVDEPZODSXAMU-UHFFFAOYSA-N
• INCHI: 1S/C11H15NO3.ClH/c1-11(12,10(14)15-2)7-8-3-5-9(13)6-4-8;/h3-6,13H,7,12H2,1-2H3;1H
• Isómeros SMILES: CC(CC1=CC=C(C=C1)O)(C(=O)OC)N.Cl
• Peso molecular: 245.70

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Clase Benzene and substituted derivatives
      • Subclass Phenethylamines

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Clase: Benzene and substituted derivatives
• Subclass: Phenethylamines
• Intermediate Tree Nodes: Not available
• Direct Parent: Amphetamines and derivatives
• Alternative Parents: Alpha amino acids and derivatives Phenylpropanes Fatty acid esters Aralkylamines 1-hydroxy-2-unsubstituted benzenoids Methyl esters Monocarboxylic acids and derivatives Organopnictogen compounds Organic oxides Monoalkylamines Hydrochlorides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aromatic homomonocyclic compounds
• Substituents: Alpha-amino acid or derivatives - Amphetamine or derivatives - Phenylpropane - 1-hydroxy-2-unsubstituted benzenoid - Fatty acid ester - Phenol - Aralkylamine - Fatty acyl - Methyl ester - Amino acid or derivatives - Carboxylic acid ester - Carboxylic acid derivative - Monocarboxylic acid or derivatives - Organooxygen compound - Organonitrogen compound - Amine - Primary aliphatic amine - Hydrocarbon derivative - Organic oxide - Organic nitrogen compound - Carbonyl group - Organopnictogen compound - Organic oxygen compound - Hydrochloride - Primary amine - Aromatic homomonocyclic compound
• Descripción: This compound belongs to the class of organic compounds known as amphetamines and derivatives. These are organic compounds containing or derived from 1-phenylpropan-2-amine.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Solubilidad: DMSO: 3.5 mg/mL (14.25 mM)；H2O: 8 mg/mL (32.56 mM)
• Sensibilidad: Moisture sensitive
• Punto de fusión (°C): 192 °C
• Peso molecular: 245.700 g/mol
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 245.082 Da
• Monoisotopic Mass: 245.082 Da
• Topological Polar Surface Area: 72.600 Ų
• Heavy Atom Count: 16
• Formal Charge: 0
• Complexity: 224.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 1
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

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