(±)-Metoprolol (+)-tartrate salt - analytical standard , Beta-1 adrenergic receptor antagonist, CAS No.56392-17-7, Beta-1 adrenergic receptor antagonist

CAS: 56392-17-7 Cat. No.: M111944 Peso molecular: 684.81 Número EC: 260-148-9
Disponible para pedir
GRADE & PURITY Analytical standard ? Analytical standard — certified-purity material for quantitative calibration. Use to prepare calibration standards and validate analytical methods.
Synonyms
NSC-757105 | SCHEMBL2051655 | Seloken | HMS3651I21 | Metoprolol tartrate | 1-[4-(2-Methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-2-propanol hemitartrate | HMS1570C08 | Metoprolol (Tartrate) | 1-(Isopropylamino)-3-(4-(2-methoxyethyl)phenoxy)-propan-2-ol 2
Storage
Store at 2-8°C
Shipped In
Wet ice
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
1g
M111944-1g
1

87,90US$

102,90US$
Guardar 15,00 US$ (14.58%)
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Why this grade

analytical standard Analytical standard for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at 2-8°C Ships Wet ice Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 9 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Sinónimos
NSC-757105 | SCHEMBL2051655 | Seloken | HMS3651I21 | Metoprolol tartrate | 1-[4-(2-Methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-2-propanol hemitartrate | HMS1570C08 | Metoprolol (Tartrate) | 1-(Isopropylamino)-3-(4-(2-methoxyethyl)phenoxy)-propan-2-ol 2
Especificaciones y pureza
analytical standard
Mecanismos bioquímicos y fisiológicos
β 1 Adrenoceptor antagonist (K i values are 47, 2960 and 10100 nM for β 1 , β 2 and β 3 , respectively). Systemically active following oral administration.
Condiciones de almacenamiento de almacenamiento
Store at 2-8°C
Enviado en
Wet ice
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Grado
Analytical standard
Tipo de acción
ANTAGONIST
Mecanismo de acción
Beta-1 adrenergic receptor antagonist
Nota
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Nombres e identificadores
Sonrisas canónicasCC(C)NCC(COC1=CC=C(C=C1)CCOC)O.CC(C)NCC(COC1=CC=C(C=C1)CCOC)O.C(C(C(=O)O)O)(C(=O)O)O
IUPAC Name2,3-dihydroxybutanedioic acid;1-[4-(2-methoxyethyl)phenoxy]-3-(propan-2-ylamino)propan-2-ol
InChIKeyYGULWPYYGQCFMP-UHFFFAOYSA-N
INCHI1S/2C15H25NO3.C4H6O6/c2*1-12(2)16-10-14(17)11-19-15-6-4-13(5-7-15)8-9-18-3;5-1(3(7)8)2(6)4(9)10/h2*4-7,12,14,16-17H,8-11H2,1-3H3;1-2,5-6H,(H,7,8)(H,9,10)
Isómeros SMILES CC(C)NCC(COC1=CC=C(C=C1)CCOC)O.CC(C)NCC(COC1=CC=C(C=C1)CCOC)O.C(C(C(=O)O)O)(C(=O)O)O
Peso molecular 684.81
Reaxy-Rn 6465966
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=6465966&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic oxygen compounds
ClaseOrganooxygen compounds
SubclassCarbohydrates and carbohydrate conjugates
Intermediate Tree Nodes Not available
Direct ParentSugar acids and derivatives
Alternative Parents Short-chain hydroxy acids and derivatives  Beta hydroxy acids and derivatives  Monosaccharides  Fatty acids and conjugates  Dicarboxylic acids and derivatives  Alpha hydroxy acids and derivatives  Secondary alcohols  Carboxylic acids  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkNot available
Substituents Beta-hydroxy acid - Short-chain hydroxy acid - Sugar acid - Alpha-hydroxy acid - Dicarboxylic acid or derivatives - Hydroxy acid - Monosaccharide - Fatty acid - Secondary alcohol - Carboxylic acid - Carboxylic acid derivative - Alcohol - Organic oxide - Hydrocarbon derivative - Carbonyl group - Aromatic homomonocyclic compound
DescripciónThis compound belongs to the class of organic compounds known as sugar acids and derivatives. These are compounds containing a saccharide unit which bears a carboxylic acid group.
External Descriptors Not available
Estructura 3D
Modelo de Estructura Química Interactiva





Objetivos asociados (humanos)
NPY2R Tchem Neuropeptide Y receptor type 2 (3731 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HEK293 (82097 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
POLK Tbio DNA polymerase kappa (8653 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BLM Tchem Bloom syndrome protein (4248 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PMP22 Tbio Peripheral myelin protein 22 (699 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B1 Tchem Solute carrier organic anion transporter family member 1B1 (2672 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CBX1 Tbio Chromobox protein homolog 1 (92434 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLCO1B3 Tchem Solute carrier organic anion transporter family member 1B3 (2517 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Objetivos asociados (no humanos)
Npy1r Neuropeptide Y receptor type 1 (8 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GCN5 Histone acetyltransferase GCN5 (89 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Npsr1 Neuropeptide S receptor (260 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
pfk 6-phospho-1-fructokinase (7870 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot NumberCertificate TypeFechaArticulo
C1729022Certificate of AnalysisMar 20, 2026 M111944
J2019258Certificate of AnalysisFeb 05, 2026 M111944
Propiedades químicas y físicas
Peso molecular684.800 g/mol
XLogP3
Hydrogen Bond Donor Count8
Hydrogen Bond Acceptor Count14
Rotatable Bond Count21
Exact Mass684.383 Da
Monoisotopic Mass684.383 Da
Topological Polar Surface Area217.000 Ų
Heavy Atom Count48
Formal Charge0
Complexity349.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count4
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count3
Citations of This Product
Referencias
1. Qingqing Yang, Jing Sun, Chuan Li, Haizhi Zhang, Weiren Xu, Changxiao Liu, Xuemin Zheng.  (2019)  Comparative research on the metabolism of metoprolol by four CYP2D6 allelic variants in vitro with LC-MS/MS.  JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS,      [PMID:31228851] [10.1016/j.jpba.2019.06.016]
2. Qinghao Cao, Chao Chen, Jun Huang, Dantong Shen, Haolin Chen, Huiqing Zhong, Zhiming Liu, Zhouyi Guo.  (2022)  Mussel-inspired hydrogels for fast fabrication of flexible SERS tape for point-of-care testing of β-blockers.  ANALYST,  147  (16): (3652-3661).  [PMID:35839093] [10.1039/D2AN00688J]
3. Weiyingxue Yang, Chuixiu Huang, Xiantao Shen.  (2022)  Water-compatible Janus molecularly imprinted particles with mouth-like opening: Rapid removal of pharmaceuticals from hospital effluents.  CHEMOSPHERE,      [PMID:35714963] [10.1016/j.chemosphere.2022.135350]
4. Xiaonan Li, Gang Xing, Xinxin Guo, Yang Wang, Zixia Hu, Maosheng Cheng, Ying Peng, Jiang Zheng.  (2022)  Identification of Metoprolol Tartrate-Derived Reactive Metabolites Possibly Correlated with Its Cytotoxicity.  CHEMICAL RESEARCH IN TOXICOLOGY,      [PMID:35575346] [10.1021/acs.chemrestox.2c00052]
5. Yu-qiong Gao, Jia Zhang, Jin-qiang Zhou, Cong Li, Nai-yun Gao, Da-qiang Yin.  (2020)  Persulfate activation by nano zero-valent iron for the degradation of metoprolol in water: influencing factors, degradation pathways and toxicity analysis.  RSC Advances,  10  (35): (20991-20999).  [PMID:35517766] [10.1039/D0RA01273D]
6. Shucheng Sun, Yujia Wang, Xin Liu, Rao Fu, Li Yang.  (2017)  Rapid and sensitive tapered-capillary microextraction combined to on-line sample stacking-capillary electrophoresis for extraction and quantification of two beta-blockers in human urine.  TALANTA,      [PMID:29332838] [10.1016/j.talanta.2017.12.035]
7. Yajiao Liu, Jingjing Bao, Lei Zhang, Chen Chao, Jianjun Guo, Yuchuan Cheng, Yuejin Zhu, Gaojie Xu.  (2017)  Ultrasensitive SERS detection of propranolol based on sandwich nanostructure of molecular imprinting polymers.  SENSORS AND ACTUATORS B-CHEMICAL,      [PMID:] [10.1016/j.snb.2017.08.018]
8. Jing Chen, Bao Qiong Li, Min Li Xu, Xue Wang, Yu Hong Jing, Hong Lin Zhai.  (2016)  Krawtchouk image moment method for the simultaneous determination of three drugs in human plasma based on fluorescence three-dimensional spectra.  TALANTA,      [PMID:27769504] [10.1016/j.talanta.2016.08.019]
9. Sui-Qin Yang, Rui-Qiu Ye, Yu-Hong Cui, Zheng-Qian Liu, Kai Sun, Yu-Ze Yu.  (2024)  Transformation of metoprolol in UV/PDS process: Role and mechanisms of degradation and polymerization.  JOURNAL OF HAZARDOUS MATERIALS,      [PMID:38733782] [10.1016/j.jhazmat.2024.134498]
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