Mildronato - ≥98% , CAS No.76144-81-5

CAS: 76144-81-5 Cat. No.: M189201 Peso molecular: 146.19 Número EC: 682-135-0

GRADE & PURITY ≥98%

Synonyms

3-[(trimethylazaniumyl)amino]propanoate | MELDONIUM [MART.] | Hydrazinium, 2-(2-carboxyethyl)-1,1,1-trimethyl-, hydroxide, inner salt | Kvaterin | Melatonin (JAN) | 73H7UDN6EC | AKOS015906002 | BCP04503 | Meldonium dihydrate, >=98% (HPLC), powder | Mildro

Storage

Conservar a 2-8°C

Shipped In

Hielo húmedo

Specifications

Sinónimos

3-[(trimethylazaniumyl)amino]propanoate | MELDONIUM [MART.] | Hydrazinium, 2-(2-carboxyethyl)-1, 1, 1-trimethyl-, hydroxide, inner salt | Kvaterin | Melatonin (JAN) | 73H7UDN6EC | AKOS015906002 | BCP04503 | Meldonium dihydrate, >=98% (HPLC), powder | Mildro

Especificaciones y pureza

≥98%

Mecanismos bioquímicos y fisiológicos

El Meldonium es un inhibidor de la γ-butirobetaína hidroxilasa (BBOX), una enzima clave en la síntesis de la carnitina. Inhibidor de la biosíntesis de L-carnitina dependiente de la GBB hidrolasa. Inhibidor competitivo de la reabsorción renal de carnitina.

Condiciones de almacenamiento de almacenamiento

Conservar a 2-8°C

Enviado en

Hielo húmedo

Nota

Siempre que sea posible, prepare y utilice las soluciones el mismo día. No obstante, si necesita preparar soluciones madre con antelación, le recomendamos que almacene la solución como alícuotas en viales herméticamente cerrados a -20°C. Por lo general, podrán utilizarse durante un mes. Antes de su uso, y antes de abrir el vial, le recomendamos que deje que el producto se equilibre a temperatura ambiente durante al menos 1 hora. ¿Necesita más consejos sobre solubilidad, uso y manipulación? Visite nuestra página de preguntas frecuentes (FAQ) para obtener más información.

Pureza

≥98%

Nombres e identificadores

• Pubchem Sid: 504756952
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504756952
• Sonrisas canónicas: C[N+](C)(C)NCCC(=O)[O-]
• IUPAC Name: 3-[(trimethylazaniumyl)amino]propanoate
• InChIKey: PVBQYTCFVWZSJK-UHFFFAOYSA-N
• INCHI: 1S/C6H14N2O2/c1-8(2,3)7-5-4-6(9)10/h7H,4-5H2,1-3H3
• Isómeros SMILES: C[N+](C)(C)NCCC(=O)[O-]
• Peso molecular: 146.19
• Reaxy-Rn: 3938272
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3938272&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Clase Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Beta amino acids and derivatives

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Clase: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives
• Direct Parent: Beta amino acids and derivatives
• Alternative Parents: Carboxylic acid salts Monocarboxylic acids and derivatives Carboxylic acids Organopnictogen compounds Organonitrogen compounds Organic salts Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Beta amino acid or derivatives - Carboxylic acid salt - Monocarboxylic acid or derivatives - Carboxylic acid - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organic salt - Organooxygen compound - Organonitrogen compound - Carbonyl group - Aliphatic acyclic compound
• Descripción: This compound belongs to the class of organic compounds known as beta amino acids and derivatives. These are amino acids having a (-NH2) group attached to the beta carbon atom.
• External Descriptors: a small molecule

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Objetivos asociados (humanos)

BBOX1 Tchem Gamma-butyrobetaine dioxygenase (162 Activities)

Discover Target: BBOX1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Objetivos asociados (no humanos)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de acción

Propiedades químicas y físicas

• Sensibilidad: Moisture sensitive.
• Peso molecular: 146.190 g/mol
• XLogP3: -2.100
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 146.106 Da
• Monoisotopic Mass: 146.106 Da
• Topological Polar Surface Area: 52.200 Ų
• Heavy Atom Count: 10
• Formal Charge: 0
• Complexity: 112.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Referencias

1. Yanyu Zhang, Chenhao Hu, Jingchuan Liu, Sirong Jiang, Qian Liu, Xin Zhou, Yiling Liu, Feibiao Song, Jian Luo.  (2026)  Tissue-specific metabolic remodeling to opposite fatty acid oxidation regulation in golden pompano identified by dual-tissue multi-omics.  AQUACULTURE,      [PMID:] [10.1016/j.aquaculture.2026.744174]