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ML213 - Moligand™, 10mM in DMSO , Activator of K v7.4, CAS No.489402-47-3, Activator of K v7.4

CAS: 489402-47-3 Cat. No.: M424236 Peso molecular: 257.37 Número EC: 803-886-4
COA
ML213 - Moligand™, 10mM in DMSO CAS No(489402-47-3) by Aladdin Scientific
Disponible para pedir
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO
Synonyms
N-(2,4,6-trimethylphenyl)bicyclo[2.2.1]heptane-6-carboxamide | ML213 | ML-213 | MLS003370512 | SMR000514557 | EX-A2551 | s6553 | Q27087011 | STK373915 | CID 3111211 | N-mesitylbicyclo[2.2.1]heptane-2-carboxamide | bicyclo[2.2.1]heptane-2-carboxylic acid (
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
★
 ·  off list, applied to all prices below.
Size
Estado
Price
Qty
1ml
M424236-1ml
2

113,90US$

133,90US$
Guardar 20,00 US$ (14.94%)
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♡ Lista de deseos ⇅ Añadir para comparar ⎙ Print page
SDS
Safety data
COA
Certificate
DS
Datasheet
SP
Spec sheet
Specifications Nombres e identificadores Documentation Advanced Data Taxonomic Classification Estructura 3D Objetivos asociados (humanos) Objetivos asociados (no humanos) Mecanismos de acción Certificados (CoA, COO, BSE/TSE y tabla de análisis) Propiedades químicas y físicas Preguntas frecuentes y artículos Calculadoras de soluciones Reseñas
🧪

Why this grade

Moligand™, 10mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Sinónimos
N-(2, 4, 6-trimethylphenyl)bicyclo[2.2.1]heptane-6-carboxamide | ML213 | ML-213 | MLS003370512 | SMR000514557 | EX-A2551 | s6553 | Q27087011 | STK373915 | CID 3111211 | N-mesitylbicyclo[2.2.1]heptane-2-carboxamide | bicyclo[2.2.1]heptane-2-carboxylic acid (
Especificaciones y pureza
Moligand™, 10mM in DMSO
Mecanismos bioquímicos y fisiológicos
Selective KV7.2 (KCNQ2) and KV7.4 (KCNQ4) channel opener (EC50values are 230 and 510 nM for KV7.2 and KV7.4 respectively). Displays > 80-fold selectivity against KV7.1, KV7.3 and KV7.5 in a thallium-based fluorescence assay. Hyperpolarizes resting membran
Condiciones de almacenamiento de almacenamiento
Store at -80°C
Enviado en
Dry ice packs + Cold packs
Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.
Grado
Moligand™
Tipo de acción
ACTIVATOR
Mecanismo de acción
Activator of K v7.4
Nombres e identificadores
Sonrisas canónicasCC1=CC(=C(C(=C1)C)NC(=O)C2CC3CCC2C3)C
IUPAC NameN-(2,4,6-trimethylphenyl)bicyclo[2.2.1]heptane-2-carboxamide
InChIKeySIQGKPGBLYKQBB-UHFFFAOYSA-N
INCHI1S/C17H23NO/c1-10-6-11(2)16(12(3)7-10)18-17(19)15-9-13-4-5-14(15)8-13/h6-7,13-15H,4-5,8-9H2,1-3H3,(H,18,19)
Isómeros SMILES CC1=CC(=C(C(=C1)C)NC(=O)C2CC3CCC2C3)C
WGK Alemania 3
Peso molecular 257.37
Reaxy-Rn 24287972
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=24287972&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassLipids and lipid-like molecules
ClasePrenol lipids
SubclassMonoterpenoids
Intermediate Tree Nodes Not available
Direct ParentBicyclic monoterpenoids
Alternative Parents Aromatic monoterpenoids  Anilides  N-arylamides  Secondary carboxylic acid amides  Organopnictogen compounds  Organic oxides  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAromatic homopolycyclic compounds
Substituents Aromatic monoterpenoid - Bicyclic monoterpenoid - Anilide - N-arylamide - Monocyclic benzene moiety - Benzenoid - Carboxamide group - Secondary carboxylic acid amide - Carboxylic acid derivative - Organic nitrogen compound - Organooxygen compound - Organonitrogen compound - Hydrocarbon derivative - Organic oxide - Carbonyl group - Organopnictogen compound - Organic oxygen compound - Aromatic homopolycyclic compound
DescripciónThis compound belongs to the class of organic compounds known as bicyclic monoterpenoids. These are monoterpenoids containing exactly 2 rings, which are fused to each other.
External Descriptors Not available
Estructura 3D
Modelo de Estructura Química Interactiva





Objetivos asociados (humanos)
KCNQ4 Tclin Potassium voltage-gated channel subfamily KQT member 4 (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
KCNQ4 Tclin Voltage-gated potassium channel subunit Kv7.4 (100 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
U2OS (164939 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ATAD5 Tbio ATPase family AAA domain-containing protein 5 (122566 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KCNQ2 Tclin Voltage-gated potassium channel, KQT; KCNQ2(Kv7.2)/KCNQ3(Kv7.3) (372 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HEK-293T (167025 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KCNQ3 Tclin Voltage-gated potassium channel KCNQ3/KCNQ5 (37 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Objetivos asociados (no humanos)
Kcnq2 Voltage-gated potassium channel subunit Kv7.2 (95 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Plasmodium falciparum (966862 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Luciferin 4-monooxygenase (66902 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Kcnq2 Potassium voltage-gated channel subfamily KQT member 2/member 3 (14 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de acción
Certificados (CoA, COO, BSE/TSE y tabla de análisis)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propiedades químicas y físicas
Peso molecular257.370 g/mol
XLogP34.200
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count1
Rotatable Bond Count2
Exact Mass257.178 Da
Monoisotopic Mass257.178 Da
Topological Polar Surface Area29.100 Ų
Heavy Atom Count19
Formal Charge0
Complexity341.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count3
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Preguntas frecuentes y artículos
Applications of Voltage-Gated Potassium Channel Modulators in Studies of Neuronal and Smooth Muscle Function
Categories: Technical articles
Tags:
voltage-gated potassium channels Kv channels modulators neuronal excitability smooth muscle membrane potential electrophysiology KCNQ pharmacology
Calculadoras de soluciones
Reseñas

Reseñas de cliente

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Compound libraries (12310) Ion channel (4039)
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