Name: MonoMethyl auristatin E - Moligand™, ≥97% , CAS No.474645-27-7
Brand: Aladdin Scientific
SKU: M303780
Availability: InStock

MonoMethyl auristatin E - Moligand™, ≥97% , CAS No.474645-27-7

CAS: 474645-27-7 Cat. No.: M303780 Peso molecular: 717.98 Número EC: 811-424-8

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MonoMethyl auristatin E - Moligand™, ≥97% CAS No(474645-27-7) by Aladdin Scientific

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Disponible para pedir

GRADE & PURITY Moligand™ ? ≥97%

Synonyms

L-Valinamide, N-methyl-L-valyl-N-((1S,2R)-4-((2S)-2-((1R,2R)-3-(((1R,2S)-2-hydroxy-1- methyl-2-phenylethyl)amino)-1-methoxy-2-methyl-3-oxopropyl)-1-pyrrolidinyl)-2- methoxy-1-((1S)-1-methylpropyl)-4-oxobutyl)-N-methyl- | Monomethyl auristatin E (MMAE) | D

Storage

Protected from light,Store at -20°C,Argon charged,Desiccated

Shipped In

Ice chest + Ice pads

Size

Estado

Price

Qty

5mg

M303780-5mg

9,90US$

10mg

M303780-10mg

10,90US$

25mg

M303780-25mg

20,90US$

31,90US$
Guardar 11,00 US$ (34.48%)

50mg

M303780-50mg

35,90US$

53,90US$
Guardar 18,00 US$ (33.40%)

100mg

M303780-100mg

54,90US$

82,90US$
Guardar 28,00 US$ (33.78%)

250mg

M303780-250mg

84,90US$

127,90US$
Guardar 43,00 US$ (33.62%)

M303780-1g

8-12 wks(?)

239,90US$

359,90US$
Guardar 120,00 US$ (33.34%)

M303780-5g

8-12 wks(?)

870,90US$

1.306,90US$
Guardar 436,00 US$ (33.36%)

Enter a quantity for the sizes you want to add.

Bulk / Custom

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Specifications Nombres e identificadores Documentation Advanced Data Taxonomic Classification Estructura 3D Objetivos asociados (humanos) Objetivos asociados (no humanos) Mecanismos de acción Certificados (CoA, COO, BSE/TSE y tabla de análisis) Propiedades químicas y físicas Preguntas frecuentes y artículos Calculadoras de soluciones Reseñas

🧪

Why this grade

Moligand™, ≥97% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Protected from light,Store at -20°C,Argon charged,Desiccated Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Sinónimos

L-Valinamide, N-methyl-L-valyl-N-((1S, 2R)-4-((2S)-2-((1R, 2R)-3-(((1R, 2S)-2-hydroxy-1- methyl-2-phenylethyl)amino)-1-methoxy-2-methyl-3-oxopropyl)-1-pyrrolidinyl)-2- methoxy-1-((1S)-1-methylpropyl)-4-oxobutyl)-N-methyl- | Monomethyl auristatin E (MMAE) | D

Especificaciones y pureza

Moligand™, ≥97%

Mecanismos bioquímicos y fisiológicos

Monomethyl Auristatin E (MMAE) is a highly potent peptidyl antimitotic agent that blocks the polymerization of tubulin. Monomethyl Auristatin E is a component of a clinically approved antibodydirected conjugates Brentuximab vedotin, Glembatumumab vedotin,

Condiciones de almacenamiento de almacenamiento

Protected from light, Store at -20°C, Argon charged, Desiccated

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Grado

Moligand™

Pureza

≥97%

Nombres e identificadores

Pubchem Sid	504766531
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504766531
Sonrisas canónicas	CCC(C)C(C(CC(=O)N1CCCC1C(C(C)C(=O)NC(C)C(C2=CC=CC=C2)O)OC)OC)N(C)C(=O)C(C(C)C)NC(=O)C(C(C)C)NC
IUPAC Name	(2S)-N-[(2S)-1-[[(3R,4S,5S)-1-[(2S)-2-[(1R,2R)-3-[[(1S,2R)-1-hydroxy-1-phenylpropan-2-yl]amino]-1-methoxy-2-methyl-3-oxopropyl]pyrrolidin-1-yl]-3-methoxy-5-methyl-1-oxoheptan-4-yl]-methylamino]-3-methyl-1-oxobutan-2-yl]-3-methyl-2-(methylamino)butanamide
InChIKey	DASWEROEPLKSEI-UIJRFTGLSA-N
INCHI	1S/C39H67N5O7/c1-13-25(6)34(43(10)39(49)33(24(4)5)42-38(48)32(40-9)23(2)3)30(50-11)22-31(45)44-21-17-20-29(44)36(51-12)26(7)37(47)41-27(8)35(46)28-18-15-14-16-19-28/h14-16,18-19,23-27,29-30,32-36,40,46H,13,17,20-22H2,1-12H3,(H,41,47)(H,42,48)/t25-,26+,27+,29-,30+,32-,33-,34-,35+,36+/m0/s1
Isómeros SMILES	CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@@H]([C@@H](C)C(=O)N[C@H](C)[C@H](C2=CC=CC=C2)O)OC)OC)N(C)C(=O)[C@H](C(C)C)NC(=O)[C@H](C(C)C)NC
Peso molecular	717.98
Reaxy-Rn	33690997
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=33690997&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organic acids and derivatives
  - Clase Peptidomimetics
    - Subclass Hybrid peptides

Kingdom	Organic compounds
Superclass	Organic acids and derivatives
Clase	Peptidomimetics
Subclass	Hybrid peptides
Intermediate Tree Nodes	Not available
Direct Parent	Hybrid peptides
Alternative Parents	Dipeptides Valine and derivatives N-acyl-alpha amino acids and derivatives Alpha amino acid amides Phenylpropanes N-acylpyrrolidines N-acyl amines Tertiary carboxylic acid amides Secondary alcohols Secondary carboxylic acid amides Dialkylamines Dialkyl ethers Azacyclic compounds Organopnictogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds Aromatic alcohols
Molecular Framework	Aromatic heteromonocyclic compounds
Substituents	Hybrid peptide - Alpha-dipeptide - Valine or derivatives - N-acyl-alpha amino acid or derivatives - Alpha-amino acid amide - N-substituted-alpha-amino acid - Alpha-amino acid or derivatives - Phenylpropane - N-acylpyrrolidine - Monocyclic benzene moiety - Fatty amide - Fatty acyl - N-acyl-amine - Benzenoid - Tertiary carboxylic acid amide - Pyrrolidine - Amino acid or derivatives - Carboxamide group - Secondary carboxylic acid amide - Secondary alcohol - Secondary amine - Carboxylic acid derivative - Organoheterocyclic compound - Azacycle - Dialkyl ether - Ether - Secondary aliphatic amine - Organopnictogen compound - Hydrocarbon derivative - Aromatic alcohol - Organic nitrogen compound - Carbonyl group - Organic oxide - Alcohol - Amine - Organonitrogen compound - Organooxygen compound - Organic oxygen compound - Aromatic heteromonocyclic compound
Descripción	This compound belongs to the class of organic compounds known as hybrid peptides. These are compounds containing at least two different types of amino acids (alpha, beta, gamma, delta) linked to each other through a peptide bond.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Estructura 3D

Objetivos asociados (humanos)

BT-474 (2113 Activities)

Lot Number	Certificate Type	Fecha	Articulo
I2525691	Certificate of Analysis	Aug 14, 2025	M303780
I2525692	Certificate of Analysis	Aug 14, 2025	M303780
J2516849	Certificate of Analysis	Aug 14, 2025	M303780
J2214456	Certificate of Analysis	Jul 10, 2025	M303780
J2214488	Certificate of Analysis	Jul 10, 2025	M303780
J2214497	Certificate of Analysis	Jul 10, 2025	M303780
J2214517	Certificate of Analysis	Jul 10, 2025	M303780
A2211833	Certificate of Analysis	Nov 05, 2024	M303780
A2211850	Certificate of Analysis	Nov 05, 2024	M303780
A2211851	Certificate of Analysis	Nov 05, 2024	M303780

Solubilidad	Solvent:DMSO, Max Conc. mg/mL: 71.8, Max Conc. mM: 100
Sensibilidad	Moisture & Light sensitive
Punto de fusión (°C)	>90°C (dec.)
Peso molecular	718.000 g/mol
XLogP3	4.100
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	20
Exact Mass	717.504 Da
Monoisotopic Mass	717.504 Da
Topological Polar Surface Area	150.000 Å²
Heavy Atom Count	51
Formal Charge	0
Complexity	1100.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	10
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

MonoMethyl auristatin E - Moligand™, ≥97% , CAS No.474645-27-7

Why this grade

Storage & shipping

Quality documents

Literature proof

Specifications

Documentation

📋 Safety Data Sheet (SDS)

✅ Certificate of Analysis (COA)

📊 Datasheet

🔬 Specification Sheet

Advanced Data

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

Reseñas de cliente

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