MoTP - Moligand™, ≥98% , CAS No.57055-82-0

CAS: 57055-82-0 Cat. No.: M275462 Peso molecular: 267.39

GRADE & PURITY Moligand™, ≥98%

Synonyms

4-(4-Morpholinobutylthio)phenol | 4-{[4-(MORPHOLIN-4-YL)BUTYL]SULFANYL}PHENOL | MoTP, >=98% (HPLC) | 4-(4-morpholin-4-ylbutylsulfanyl)phenol | HY-114745 | SCHEMBL11529117 | CBDivE_010514 | MoTP | AKOS000560293 | DTXSID70389177 | MFCD00642470 | 4-[[4-(4-MO

Storage

Store at -20°C,Argon charged,Desiccated

Shipped In

Ice chest + Ice pads

Descripción general

MoTP is a specific platelet activating factor receptor antagonist and can induce melanocyte ablation. MoTP can be used for the research of cancer.

Specifications

Sinónimos

4-(4-Morpholinobutylthio)phenol | 4-{[4-(MORPHOLIN-4-YL)BUTYL]SULFANYL}PHENOL | MoTP, >=98% (HPLC) | 4-(4-morpholin-4-ylbutylsulfanyl)phenol | HY-114745 | SCHEMBL11529117 | CBDivE_010514 | MoTP | AKOS000560293 | DTXSID70389177 | MFCD00642470 | 4-[[4-(4-MO

Especificaciones y pureza

Moligand™, ≥98%

Mecanismos bioquímicos y fisiológicos

Specific platelet activating factor (PAF)-receptor antagonist (IC 50 = 0.28 μM). PLC inhibitor (IC 50 = 1.05 μM). PAF-induced hypotension inhibitor. Active in vivo and in vitro .

Condiciones de almacenamiento de almacenamiento

Store at -20°C, Argon charged, Desiccated

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Grado

Moligand™

Tipo de acción

ANTAGONIST

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureza

≥98%

Nombres e identificadores

• Sonrisas canónicas: C1COCCN1CCCCSC2=CC=C(C=C2)O
• IUPAC Name: 4-(4-morpholin-4-ylbutylsulfanyl)phenol
• InChIKey: YHKNLUTUXZDOQI-UHFFFAOYSA-N
• INCHI: 1S/C14H21NO2S/c16-13-3-5-14(6-4-13)18-12-2-1-7-15-8-10-17-11-9-15/h3-6,16H,1-2,7-12H2
• Isómeros SMILES: C1COCCN1CCCCSC2=CC=C(C=C2)O
• Peso molecular: 267.39
• Reaxy-Rn: 986799
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=986799&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organosulfur compounds
    • Clase Thioethers
      • Subclass Aryl thioethers

• Kingdom: Organic compounds
• Superclass: Organosulfur compounds
• Clase: Thioethers
• Subclass: Aryl thioethers
• Intermediate Tree Nodes: Not available
• Direct Parent: Aryl thioethers
• Alternative Parents: Thiophenol ethers Alkylarylthioethers 1-hydroxy-2-unsubstituted benzenoids Morpholines Benzene and substituted derivatives Trialkylamines Sulfenyl compounds Oxacyclic compounds Dialkyl ethers Azacyclic compounds Hydrocarbon derivatives
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: Aryl thioether - Thiophenol ether - 1-hydroxy-2-unsubstituted benzenoid - Phenol - Alkylarylthioether - Monocyclic benzene moiety - Morpholine - Oxazinane - Benzenoid - Tertiary amine - Tertiary aliphatic amine - Dialkyl ether - Ether - Oxacycle - Azacycle - Organoheterocyclic compound - Sulfenyl compound - Organonitrogen compound - Organooxygen compound - Hydrocarbon derivative - Organic nitrogen compound - Amine - Organic oxygen compound - Aromatic heteromonocyclic compound
• Descripción: This compound belongs to the class of organic compounds known as aryl thioethers. These are organosulfur compounds containing a thioether group that is substituted by an aryl group.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Solubilidad: Soluble in DMSO to 25 mM and in ethanol to 25 mM
• Sensibilidad: light sensitive
• Peso molecular: 267.390 g/mol
• XLogP3: 2.500
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 6
• Exact Mass: 267.129 Da
• Monoisotopic Mass: 267.129 Da
• Topological Polar Surface Area: 58.000 Ų
• Heavy Atom Count: 18
• Formal Charge: 0
• Complexity: 214.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1