GRADE & PURITY ≥99%

Synonyms

Ac-D-Leu-OH | Leucine, N-acetyl-, D- | HY-Y1080 | AC-22376 | Acetylleucine, D- | BRD-K05831461-001-01-8 | WXNXCEHXYPACJF-SSDOTTSWSA-N | EN300-321381 | NCGC00094935-02 | 91WU82GA22 | A20910 | (R)-acetylleucine | N-acetyl-(D)-leucine | SCHEMBL714003 | AKOS0

Storage

Conservar a -20°C

Shipped In

Hielera + almohadillas de hielo

Descripción general

La N-acetil-D-leucina puede utilizarse con otros aminoácidos D-aminoacilados como sustrato para la identificación, diferenciación y caracterización de D-aminoacilasa(s)/amidohidrolasa(s).

Specifications

Sinónimos

Ac-D-Leu-OH | Leucine, N-acetyl-, D- | HY-Y1080 | AC-22376 | Acetylleucine, D- | BRD-K05831461-001-01-8 | WXNXCEHXYPACJF-SSDOTTSWSA-N | EN300-321381 | NCGC00094935-02 | 91WU82GA22 | A20910 | (R)-acetylleucine | N-acetyl-(D)-leucine | SCHEMBL714003 | AKOS0

Especificaciones y pureza

≥99%

Mecanismos bioquímicos y fisiológicos

La N-acetil-D-leucina es un sustrato de la D-aminoacilasa de Alcaligenes xylosoxydans subsp. xylosoxydans A-6. La N-acetil-D-leucina se utiliza para ayudar a diferenciar a los miembros de la superfamilia de enzimas amidohidrolasas. Es un sustrato preferid

Condiciones de almacenamiento de almacenamiento

Conservar a -20°C

Enviado en

Hielera + almohadillas de hielo

Pureza

≥99%

Nombres e identificadores

• Pubchem Sid: 504760430
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504760430
• Sonrisas canónicas: CC(C)CC(C(=O)O)NC(=O)C
• IUPAC Name: (2R)-2-acetamido-4-methylpentanoic acid
• InChIKey: WXNXCEHXYPACJF-SSDOTTSWSA-N
• INCHI: 1S/C8H15NO3/c1-5(2)4-7(8(11)12)9-6(3)10/h5,7H,4H2,1-3H3,(H,9,10)(H,11,12)/t7-/m1/s1
• Isómeros SMILES: CC(C)C[C@H](C(=O)O)NC(=O)C
• WGK Alemania: 3
• Peso molecular: 173.21
• Reaxy-Rn: 1724848
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1724848&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Clase Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Alpha amino acids and derivatives
            • Level7 Leucine and derivatives

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Clase: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives - Alpha amino acids and derivatives
• Direct Parent: Leucine and derivatives
• Alternative Parents: N-acyl-alpha amino acids Methyl-branched fatty acids Acetamides Secondary carboxylic acid amides Monocarboxylic acids and derivatives Carboxylic acids Organopnictogen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Leucine or derivatives - N-acyl-alpha-amino acid - N-acyl-alpha amino acid or derivatives - Branched fatty acid - Methyl-branched fatty acid - Fatty acyl - Fatty acid - Acetamide - Carboxamide group - Secondary carboxylic acid amide - Carboxylic acid - Monocarboxylic acid or derivatives - Organonitrogen compound - Organic oxide - Organopnictogen compound - Organic nitrogen compound - Organic oxygen compound - Carbonyl group - Organooxygen compound - Hydrocarbon derivative - Aliphatic acyclic compound
• Descripción: This compound belongs to the class of organic compounds known as leucine and derivatives. These are compounds containing leucine or a derivative thereof resulting from reaction of leucine at the amino group or the carboxy group, or from the replacement of any hydrogen of glycine by a heteroatom.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Mecanismos de acción

Propiedades químicas y físicas

• Rotación específica [α]: 23 ° (C=4, EtOH)
• Peso molecular: 173.210 g/mol
• XLogP3: 0.500
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 173.105 Da
• Monoisotopic Mass: 173.105 Da
• Topological Polar Surface Area: 66.400 Ų
• Heavy Atom Count: 12
• Formal Charge: 0
• Complexity: 177.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 1
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Referencias

1. Yaoguo Wang, Jie Sun, Weiwei Tang, Junbo Gong.  (2023)  Green chiral separation of racemic mixture via crystallization induced deracemization process synergistically intensified by ultrasound and temperature cycling.  CHEMICAL ENGINEERING SCIENCE,      [PMID:] [10.1016/j.ces.2023.119115]