N-Methyl-D-glucamine - ≥99% , CAS No.6284-40-8

CAS: 6284-40-8 Cat. No.: M106762 Peso molecular: 195.21 Beilstein Registry Number: 385906 Número EC: 228-506-9

GRADE & PURITY ≥99%

Synonyms

Z1255485274 | 6HG8UB2MUY | A834035 | Meglumine 100 microg/mL in Acetonitrile | CAS-6284-40-8 | Meglumine (JP17/USP/INN) | MEGLUMINE [II] | AB00430469-03 | Meglumine, Pharmaceutical Secondary Standard; Certified Reference Material | Megluminum [INN-Latin]

Storage

Room temperature,Argon charged

Shipped In

Normal

Descripción general

N-Methyl-D-glucamine, also known as methylglucamine, is an organic compound that belongs to the class of amino sugars. It is commonly used in pharmaceutical and biochemical applications as a resolving and buffering agent. Salts of N-methyl-D-glucamine have also been used for X-ray contrast media and nuclear imaging agents.

Specifications

Sinónimos

Z1255485274 | 6HG8UB2MUY | A834035 | Meglumine 100 microg/mL in Acetonitrile | CAS-6284-40-8 | Meglumine (JP17/USP/INN) | MEGLUMINE [II] | AB00430469-03 | Meglumine, Pharmaceutical Secondary Standard; Certified Reference Material | Megluminum [INN-Latin]

Especificaciones y pureza

≥99%

Condiciones de almacenamiento de almacenamiento

Room temperature, Argon charged

Enviado en

Normal

Pureza

≥99%

Nombres e identificadores

• Pubchem Sid: 488180831
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488180831
• Sonrisas canónicas: CNCC(C(C(C(CO)O)O)O)O
• IUPAC Name: (2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol
• InChIKey: MBBZMMPHUWSWHV-BDVNFPICSA-N
• INCHI: 1S/C7H17NO5/c1-8-2-4(10)6(12)7(13)5(11)3-9/h4-13H,2-3H2,1H3/t4-,5+,6+,7+/m0/s1
• Isómeros SMILES: CNC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O
• WGK Alemania: 3
• CAS alternativo: 90191-92-7
• Peso molecular: 195.21
• Beilstein: 385906
• Reaxy-Rn: 2324336
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2324336&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic oxygen compounds
    • Clase Organooxygen compounds
      • Subclass Carbohydrates and carbohydrate conjugates
        • Level5 Monosaccharides
          • Level6 Hexoses

• Kingdom: Organic compounds
• Superclass: Organic oxygen compounds
• Clase: Organooxygen compounds
• Subclass: Carbohydrates and carbohydrate conjugates
• Intermediate Tree Nodes: Monosaccharides
• Direct Parent: Hexoses
• Alternative Parents: 1,3-aminoalcohols Secondary alcohols 1,2-aminoalcohols Polyols Dialkylamines Primary alcohols Organopnictogen compounds Hydrocarbon derivatives
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Hexose monosaccharide - 1,3-aminoalcohol - Secondary alcohol - 1,2-aminoalcohol - Secondary amine - Polyol - Secondary aliphatic amine - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Primary alcohol - Organonitrogen compound - Amine - Alcohol - Aliphatic acyclic compound
• Descripción: This compound belongs to the class of organic compounds known as hexoses. These are monosaccharides in which the sugar unit is a is a six-carbon containing moeity.
• External Descriptors: secondary amino compound - hexosamine

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Objetivos asociados (humanos)

ADRB1 Tclin Adrenergic receptor beta (1214 Activities)

Discover Target: ADRB1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Objetivos asociados (no humanos)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de acción

Propiedades químicas y físicas

• Solubilidad: Soluble in water.
• Sensibilidad: Air & Moisture sensitive
• Rotación específica [α]: -16.5 ° (C=2, H2O)
• Punto de ebullición (°C): 210 °C/1013 hPa
• Punto de fusión (°C): 129-131.5 °C (lit.)
• Peso molecular: 195.210 g/mol
• XLogP3: -2.800
• Hydrogen Bond Donor Count: 6
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 6
• Exact Mass: 195.111 Da
• Monoisotopic Mass: 195.111 Da
• Topological Polar Surface Area: 113.000 Ų
• Heavy Atom Count: 13
• Formal Charge: 0
• Complexity: 134.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 4
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Referencias

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3. Tongtong Pan, Xiangmei Cui.  (2023)  Gelatin aerogel with good mechanical properties and adjustable physical properties for boron adsorption from salt lake brines: An optimized process.  INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,      [PMID:37597634] [10.1016/j.ijbiomac.2023.126403]

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