N-Methylacetamide - ≥99% , CAS No.79-16-3

CAS: 79-16-3 Cat. No.: M106450 Peso molecular: 73.09 Beilstein Registry Number: 1071255 Número EC: 201-182-6

GRADE & PURITY ≥99%

Synonyms

M0133 | Tox21_300192 | A9897 | N-Methylacetamide, purum, >=98.0% (GC) | NCGC00247922-01 | X 44 | CH3CONHCH3 | Acetamide, methyl- | FT-0654956 | EINECS 201-182-6 | N-Methyl acetamide | Acetamide, N-methyl- | N-methylacetamide(NMA) | Acetylmethylamine | NSC

Storage

Argon charged,Room temperature

Shipped In

Normal

Specifications

Sinónimos

M0133 | Tox21_300192 | A9897 | N-Methylacetamide, purum, >=98.0% (GC) | NCGC00247922-01 | X 44 | CH3CONHCH3 | Acetamide, methyl- | FT-0654956 | EINECS 201-182-6 | N-Methyl acetamide | Acetamide, N-methyl- | N-methylacetamide(NMA) | Acetylmethylamine | NSC

Especificaciones y pureza

≥99%

Condiciones de almacenamiento de almacenamiento

Argon charged, Room temperature

Enviado en

Normal

Pureza

≥99%

Nombres e identificadores

• Pubchem Sid: 488180102
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488180102
• Sonrisas canónicas: CC(=O)NC
• IUPAC Name: N-methylacetamide
• InChIKey: OHLUUHNLEMFGTQ-UHFFFAOYSA-N
• INCHI: 1S/C3H7NO/c1-3(5)4-2/h1-2H3,(H,4,5)
• Isómeros SMILES: CC(=O)NC
• WGK Alemania: 2
• RTECS: AC5960000
• Peso molecular: 73.09
• Beilstein: 1071255
• Reaxy-Rn: 1071255
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1071255&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Clase Carboximidic acids and derivatives
      • Subclass Carboximidic acids

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Clase: Carboximidic acids and derivatives
• Subclass: Carboximidic acids
• Intermediate Tree Nodes: Not available
• Direct Parent: Carboximidic acids
• Alternative Parents: Propargyl-type 1,3-dipolar organic compounds Organopnictogen compounds Organooxygen compounds Organonitrogen compounds Hydrocarbon derivatives
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Carboximidic acid - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Hydrocarbon derivative - Organooxygen compound - Organonitrogen compound - Aliphatic acyclic compound
• Descripción: This compound belongs to the class of organic compounds known as carboximidic acids. These are organic acids with the general formula RC(=N)-OH (R=H, organic group).
• External Descriptors: monocarboxylic acid amide - acetamides

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Mecanismos de acción

Propiedades químicas y físicas

• Solubilidad: Soluble in water (1X10+6 mg/L @ 20 deg C), chloroform. Soluble in alcohol, ether, acetone, benzene.
• Sensibilidad: Light sensitive.
• Punto de congelación (°C): 30 °C
• Índice de refracción: 1.433
• Punto de inflamación (°F): 240.8℉
• Punto de inflamación (°C): 116℃
• Punto de ebullición (°C): 204-206°C
• Punto de fusión (°C): 26-28°C
• Peso molecular: 73.090 g/mol
• XLogP3: -1.100
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 73.0528 Da
• Monoisotopic Mass: 73.0528 Da
• Topological Polar Surface Area: 29.100 Ų
• Heavy Atom Count: 5
• Formal Charge: 0
• Complexity: 42.200
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Referencias

1. Yaowu Li, Peiyan Sun, Jian Chen, Xiuling Zha, Xueqing Tang, Zhiwei Chen, Yanan Zhang, Shan Cong, Fengxia Geng, Zhigang Zhao.  (2023)  Colorful Electrochromic Displays with High Visual Quality Based on Porous Metamaterials.  ADVANCED MATERIALS,  35  (23): (2300116).  [PMID:36921294] [10.1002/adma.202300116]

2. Yuanyuan Cao, Shuyi Shan, Yitong Lu, Jialu Luo, Yilin Li, Rongzhang Hao.  (2022)  Tuning toxic properties of polyethylene glycol-based deep eutectic solvents for achieving greener solvents.  JOURNAL OF MOLECULAR LIQUIDS,      [PMID:] [10.1016/j.molliq.2022.120879]

3. Ying Zhang, Hejie Wang, Qintang Li, Xiao Chen.  (2022)  Gelation behavior and supramolecular chirality of a BTA derivative in a deep eutectic solvent.  Soft Matter,  18  (16): (3241-3248).  [PMID:35393998] [10.1039/D2SM00028H]

4. Zizhao Qian, Yuanxiang Xiao, Xujun Zhang, Qing Li, Lujie Wang, Feiya Fu, Hongyan Diao, Xiangdong Liu.  (2022)  Bio-based epoxy resins derived from diphenolic acid via amidation showing enhanced performance and unexpected autocatalytic effect on curing.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2022.135022]

5. Hao Liu, Baomin Fan, Zining Liu, Xiaoqi Zhao, Biao Yang, Xingwen Zheng, Hua Hao.  (2021)  Electronic effects on protective mechanism of electropolymerized coatings based on N-substituted aniline derivatives for mild steel in saline solution.  JOURNAL OF INDUSTRIAL AND ENGINEERING CHEMISTRY,      [PMID:] [10.1016/j.jiec.2021.11.004]

6. Yan Ji, Xiaoliang Yang, Zhi Ji, Linhui Zhu, Nana Ma, Dejun Chen, Xianbin Jia, Junming Tang, Yilin Cao.  (2020)  DFT-Calculated IR Spectrum Amide I, II, and III Band Contributions of N-Methylacetamide Fine Components.  ACS Omega,      [PMID:32337419] [10.1021/acsomega.9b04421]

7. Pengcheng Hu, Wei Jiang, Lijuan Zhong, Shufeng Zhou.  (2018)  Physicochemical properties of amide–AlCl3 based ionic liquid analogues and their mixtures with copper salt.  CHINESE JOURNAL OF CHEMICAL ENGINEERING,      [PMID:] [10.1016/j.cjche.2018.06.018]

8. Pengcheng Hu, Yadong Wang, Xianghai Meng, Rui Zhang, Haiyan Liu, Chunming Xu, Zhichang Liu.  (2016)  Isobutane alkylation with 2-butene catalyzed by amide-AlCl3-based ionic liquid analogues.  FUEL,      [PMID:] [10.1016/j.fuel.2016.10.099]

9. Xingdu Chen, Chengjian Yang, Weiwei Wang, Bizhou Ge, Jun Zhang, Yucan Liu, Yaping Nan.  (2016)  Biodegradation of N,N-dimethylacetamide by Rhodococcus sp. strain B83 isolated from the rhizosphere of pagoda tree.  Journal of Environmental Sciences,      [PMID:28372764] [10.1016/j.jes.2016.05.013]

10. Pengcheng Hu, Rui Zhang, Xianghai Meng, Haiyan Liu, Chunming Xu, Zhichang Liu.  (2016)  Structural and Spectroscopic Characterizations of Amide–AlCl3-Based Ionic Liquid Analogues.  INORGANIC CHEMISTRY,      [PMID:26848508] [10.1021/acs.inorgchem.5b02744]

11. Hui Li, Guoping Zhang, Libo Deng, Rong Sun, Xing Ou-Yang.  (2014)  Thermally responsive behaviour of the electrical resistance of electrospun P(NIPAm-co-NMA)/Ag composite nanofibers.  RSC Advances,  5  (9): (6413-6418).  [PMID:] [10.1039/C4RA12662A]

12. Pan Hui, Wang Lei, Shi Yu, Sheng Chuanchao, Yang Sixie, He Ping, Zhou Haoshen.  (2024)  A solid-state lithium-ion battery with micron-sized silicon anode operating free from external pressure.  Nature Communications,  15  (1): (1-12).  [PMID:38480726] [10.1038/s41467-024-46472-9]

13. Deyan Du, Tatsuo Kaneko, Weifu Dong, Mingqing Chen, Dongjian Shi.  (2025)  Biomimetic Spinning of Strong and Hyperstable Eutectogel Fibers for Multifunctional Ionotronics.  ACS Applied Polymer Materials,      [PMID:] [10.1021/acsapm.4c03999]

14. Kaixuan Zhou, Xinke Dai, Long Zhang, Hongtao Liu, Tong Li, Xiaoming Zhang, Jiawei Wen, Guoyong Huang, Shengming Xu.  (2024)  Enhancing Stability and Safety of Commercial Solid-State Lithium Batteries Through Ternary Eutectic Solvents for Solid-State Electrolyte Interface Modification.  Advanced Energy Materials,      [PMID:] [10.1002/aenm.202402782]

15. Jiaxian Wang, Tiansheng Bai, Yihong Liang, Lin Xie, Hongqiang Zhang, Zhen Zeng, Siyu Fang, Dandan Gao, Wanbao Wu, Zhenglin Hu, Jingyu Lu, Jiaheng Zhang, Lijie Ci, Deping Li.  (2025)  Lithium Nitrate-Mediated Low-Volatile Deep Eutectic Electrolyte for Highly Stable Lithium–Oxygen Batteries.  ACS Nano,      [PMID:40088179] [10.1021/acsnano.4c18523]

16. Yu Chen, Yaxue Shen, Zicheng Liu, Mingshuai Yang, Yuqing Zhang, Zihang Niu, Yanlong Wang, Minghui Feng, Zhuojia Shi.  (2024)  Natural Low-Melting Mixture Solvents for Green Recovery of Spent All-Solid-State Sodium-Ion Batteries with Superior Efficiency over Lithium-Ion Batteries.  ChemSusChem,      [PMID:39648947] [10.1002/cssc.202402457]

17. Yu Chen, Yaxue Shen, Zhuojia Shi, Ziyang Zhang, Qing Zhang, Yanlong Wang, Minghui Feng, Chenyang Wang.  (2024)  Recovery of all-solid-state sodium-ion batteries cathode and solid electrolyte using deep eutectic solvents as green solvents.  SEPARATION AND PURIFICATION TECHNOLOGY,      [PMID:] [10.1016/j.seppur.2024.130473]

18. Yu Chen, Zhuojia Shi, Xueqing Zhang, Chenyang Wang, Yanlong Wang, Zihang Niu, Yuqing Zhang, Minghui Feng.  (2024)  Recycling Solid Electrolytes from All-Solid-State Lithium-Ion Batteries by Using Deep Eutectic Solvents as Green Extractants.  ChemSusChem,      [PMID:39512143] [10.1002/cssc.202402126]

19. Yunhui Kuang, Yazhuo Xue, Zheng Zhang, Lvpeng Yang, Tong Bie, Rui Li, Wenxi Liang, Naigen Zhou, Ming Shao.  (2025)  Strategic regulation of crystallization kinetics to achieve efficient pure-red quasi-2D perovskite light-emitting diodes.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.160278]

20. Mian Hu, Jiayi Zheng, Zhiheng Ye, Yufan Jin, Xinyu Pan, Jiahui Huang, Yage Zhang, Junliang Wang, Zhong-Ting Hu, Zhiyan Pan.  (2025)  Subcritical catalytic water oxidation for conversion DMAC waste carbon resources to acetic acid.  Journal of Environmental Chemical Engineering,      [PMID:] [10.1016/j.jece.2025.115965]

21. Wang Yuliang, Liu Zihao, Liu Tong, Zhou Wenjun, Zhang Zhijia, Zhang Songsong, Wang Guojun, Wang Qiang, Ma Teng, Wei Hao.  (2024)  Synthesis and Antibacterial Activity of Capsaicin Derivatives Containing Phenolic Hydroxyl Groups.  ChemistrySelect,  9  (30): (e202401299).  [PMID:] [10.1002/slct.202401299]

22. Cong Yang, Xinnian Xia, Suirong Fu, Fangtao Liu, Wensheng Li.  (2025)  Synthesis of a tetra-functional bio-based epoxy monomer for high-performance flame-retardant thermosets and non-destructively recyclable carbon fiber composites.  EUROPEAN POLYMER JOURNAL,      [PMID:] [10.1016/j.eurpolymj.2025.114164]

23. Yu Chen, Zhuojia Shi, Zhenghui Liu, Yaxue Shen, Yanlong Wang, Minghui Feng, Qi Liu, Zheng Li.  (2025)  Room-temperature, time-efficient and sustainable recycling of solid electrolytes from all-solid-state lithium-ion batteries.  SEPARATION AND PURIFICATION TECHNOLOGY,      [PMID:] [10.1016/j.seppur.2025.134867]

24. Li Pan, Yongfeng Bu, Hongyu Zhang, Zhaomin Zhu, Hui Li, Hongyu Liang.  (2025)  Ternary zinc-based deep eutectic solvents for durable zinc-ion capacitors capable of withstanding extreme high temperatures.  JOURNAL OF POWER SOURCES,      [PMID:] [10.1016/j.jpowsour.2025.238397]

25. Cong Yang, Xinnian Xia, Yale Xiao, Guoqing Wei, Yanbing Lu.  (2024)  Efficient degradation and recycling of carbon fiber reinforced epoxy composite wastes under mild conditions by constructing dual dynamic covalent networks.  POLYMER DEGRADATION AND STABILITY,      [PMID:] [10.1016/j.polymdegradstab.2024.111102]

26. Yu Chen, Xueqing Zhang, Chenyang Wang, Zhuojia Shi, Xihou Wang, Jiayi Dong, Yanlong Wang, Minghui Feng.  (2025)  Green recovery of solid electrolytes from all-solid-state lithium-ion batteries by low-melting mixture solvents with tunable physical properties.  PHYSICAL CHEMISTRY CHEMICAL PHYSICS,      [PMID:40423090] [10.1039/D4CP04684F]

27. Jianbo Deng, Mingjun Chen, Xiang Zhang, Hulin Zhang, Liping Hu, Shuokun Sun, Jiupeng Zhao, Yao Li.  (2025)  Water-in-eutectogel electrolytes for scalable solid-state electrochromic devices.  CHEMICAL ENGINEERING JOURNAL,      [PMID:] [10.1016/j.cej.2025.163746]

28. Yu Chen, Zhuojia Shi, Yuqing Zhang, Yaxue Shen, Zheng Li, Yanlong Wang, Minghui Feng, Qi Liu, Xiaojie Zhao.  (2025)  Screening 100 Low-Melting Mixture Solvents for Scale-Up and Tunable Recovery of Solid Electrolytes from All-Solid-State Lithium-Ion Batteries by Tailoring Acidity.  INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH,      [PMID:] [10.1021/acs.iecr.4c04971]