N,N-Bis(2-hydroxyethyl)glycine - Ultra pure, ≥99.5%(T) , CAS No.150-25-4

CAS: 150-25-4 Cat. No.: B110906 Peso molecular: 163.17 Beilstein Registry Number: 1769362 Número EC: 205-755-1

GRADE & PURITY Ultra pure, ≥99.5%(T)

Synonyms

Bicine

Storage

Room temperature,Argon charged

Shipped In

Normal

Descripción general

Bicine is a zwitterionic amino acid buffer, active in the pH 7.6-9.0 range (pKa of 8.26 at 25°C). Recommended buffer for low temperature biochemical work. Bicine is used for the preparation of stable substrate solution for serum guanase determination. The use of bicine in a thin layer ion exchange chromatography method for protein resolution has been published. Bicine has been utilized in peptide and protein crystallization. A kinetic study of a quaternary transition-state analogue complex of creatine kinase used bicine in the reaction buffer. A multiphasic buffer system for SDS-PAGE of proteins and peptides that incorporates bicine has been described.
Recommended buffer for low temperature biochemical work.Used in the preparation of stable substrate solution for serum guanase determination.Spacer in plasma protein fractionation with Sephadex? by isotachophoresis.

Specifications

Sinónimos

Bicine

Especificaciones y pureza

Ultra pure, ≥99.5%(T)

Condiciones de almacenamiento de almacenamiento

Room temperature, Argon charged

Enviado en

Normal

Grado

Ultra pure

Pureza

≥99.5%(T)

Nombres e identificadores

• Sonrisas canónicas: C(CO)N(CCO)CC(=O)O
• IUPAC Name: 2-[bis(2-hydroxyethyl)amino]acetic acid
• InChIKey: FSVCELGFZIQNCK-UHFFFAOYSA-N
• INCHI: 1S/C6H13NO4/c8-3-1-7(2-4-9)5-6(10)11/h8-9H,1-5H2,(H,10,11)
• Isómeros SMILES: C(CO)N(CCO)CC(=O)O
• WGK Alemania: 1
• RTECS: MB9700000
• Peso molecular: 163.17
• Beilstein: 1769362
• Reaxy-Rn: 1769362
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1769362&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Clase Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Alpha amino acids and derivatives
            • Level7 Alpha amino acids

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Clase: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives - Alpha amino acids and derivatives
• Direct Parent: Alpha amino acids
• Alternative Parents: Trialkylamines Amino acids 1,2-aminoalcohols Monocarboxylic acids and derivatives Carboxylic acids Primary alcohols Organopnictogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: Alpha-amino acid - 1,2-aminoalcohol - Amino acid - Tertiary aliphatic amine - Tertiary amine - Alkanolamine - Carboxylic acid - Monocarboxylic acid or derivatives - Organic nitrogen compound - Primary alcohol - Organooxygen compound - Organonitrogen compound - Hydrocarbon derivative - Organic oxide - Carbonyl group - Amine - Organopnictogen compound - Organic oxygen compound - Alcohol - Aliphatic acyclic compound
• Descripción: This compound belongs to the class of organic compounds known as alpha amino acids. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon).
• External Descriptors: bicine

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Solubilidad: Soluble in water (1M) at 20 °C, ethanol (slightly), ether (slightly), and chloroform (slightly).
• Sensibilidad: Hygroscopic
• Punto de fusión (°C): 190-192°C
• Peso molecular: 163.170 g/mol
• XLogP3: -3.800
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 6
• Exact Mass: 163.084 Da
• Monoisotopic Mass: 163.084 Da
• Topological Polar Surface Area: 81.000 Ų
• Heavy Atom Count: 11
• Formal Charge: 0
• Complexity: 111.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Referencias

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