N,N'-Dibencilquinazolina-2,4-diamina - ≥99% , CAS No.177355-84-9

CAS: 177355-84-9 Cat. No.: D275881 Peso molecular: 340.42 Número EC: 695-484-9

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N,N'-Dibencilquinazolina-2,4-diamina - ≥99% CAS No(177355-84-9) by Aladdin Scientific

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Disponible para pedir

GRADE & PURITY ≥99%

Synonyms

bencil-[2-(bencilamino)quinazolin-4-il]amina;clorhidrato | KSC-16-67 | BCP07830 | KSC-231-18-1 | Oprea1_067556 | Z57159630 | N2,N4-dibencilquinazolina-2,4-diamina | SW208073-2 | 2,4-Quinazolinediamina, N,N'-bis(fenilmetil)| KUC105555N-02 | s7199 | K

Storage

Conservar a -20°C

Shipped In

Hielera + almohadillas de hielo

Descripción general Specifications Nombres e identificadores Documentation Advanced Data Taxonomic Classification Estructura 3D Objetivos asociados (humanos) Objetivos asociados (no humanos) Mecanismos de acción Certificados (CoA, COO, BSE/TSE y tabla de análisis) Propiedades químicas y físicas Calculadoras de soluciones Reseñas

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Why this grade

≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Conservar a -20°C Ships Hielera + almohadillas de hielo Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Descripción general

El producto puede almacenarse hasta 12 meses.

Aplicación

Se trataron células HeLa con DBeQ y se estudiaron los efectos sobre la ubiquitinación in vivo y la dislocación de proteínas mediante imágenes de células vivas.

Specifications

Sinónimos

bencil-[2-(bencilamino)quinazolin-4-il]amina;clorhidrato | KSC-16-67 | BCP07830 | KSC-231-18-1 | Oprea1_067556 | Z57159630 | N2, N4-dibencilquinazolina-2, 4-diamina | SW208073-2 | 2, 4-Quinazolinediamina, N, N'-bis(fenilmetil) | KUC105555N-02 | s7199 | K

Especificaciones y pureza

≥99%

Mecanismos bioquímicos y fisiológicos

Inhibidor selectivo, potente, reversible y competitivo con ATP de la ATPasa p97 (IC 50 = 1, 5 μM). Inhibe varios procesos celulares, como la degradación asociada al RE, la degradación de la fusión de ubiquitina y la maduración de los autofagosomas. DBeQ es

Fuente

Synthetic

Condiciones de almacenamiento de almacenamiento

Conservar a -20°C

Enviado en

Hielera + almohadillas de hielo

Nota

Siempre que sea posible, prepare y utilice las soluciones el mismo día. No obstante, si necesita preparar soluciones madre con antelación, le recomendamos que almacene la solución como alícuotas en viales herméticamente cerrados a -20°C. Por lo general, podrán utilizarse durante un mes. Antes de su uso, y antes de abrir el vial, le recomendamos que deje que el producto se equilibre a temperatura ambiente durante al menos 1 hora. ¿Necesita más consejos sobre solubilidad, uso y manipulación? Visite nuestra página de preguntas frecuentes (FAQ) para obtener más información.

Pureza

≥99%

Nombres e identificadores

Pubchem Sid	504759829
Pubchem Sid Url	https://pubchem.ncbi.nlm.nih.gov/substance/504759829
Sonrisas canónicas	C1=CC=C(C=C1)CNC2=NC(=NC3=CC=CC=C32)NCC4=CC=CC=C4
IUPAC Name	2-N,4-N-dibenzylquinazoline-2,4-diamine
InChIKey	QAIMUUJJAJBPCL-UHFFFAOYSA-N
INCHI	1S/C22H20N4/c1-3-9-17(10-4-1)15-23-21-19-13-7-8-14-20(19)25-22(26-21)24-16-18-11-5-2-6-12-18/h1-14H,15-16H2,(H2,23,24,25,26)
Isómeros SMILES	C1=CC=C(C=C1)CNC2=NC(=NC3=CC=CC=C32)NCC4=CC=CC=C4
Peso molecular	340.42
Reaxy-Rn	7440169
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=7440169&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

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🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - Clase Diazanaphthalenes
    - Subclass Benzodiazines
      - Level5 Quinazolines
        Level6 Quinazolinamines

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Clase	Diazanaphthalenes
Subclass	Benzodiazines
Intermediate Tree Nodes	Quinazolines
Direct Parent	Quinazolinamines
Alternative Parents	Benzylamines Secondary alkylarylamines Aminopyrimidines and derivatives Imidolactams Heteroaromatic compounds Azacyclic compounds Organopnictogen compounds Hydrocarbon derivatives
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	Quinazolinamine - Benzylamine - Aminopyrimidine - Secondary aliphatic/aromatic amine - Imidolactam - Benzenoid - Pyrimidine - Monocyclic benzene moiety - Heteroaromatic compound - Azacycle - Secondary amine - Amine - Organopnictogen compound - Organonitrogen compound - Organic nitrogen compound - Hydrocarbon derivative - Aromatic heteropolycyclic compound
Descripción	This compound belongs to the class of organic compounds known as quinazolinamines. These are heterocyclic aromatic compounds containing a quianazoline moiety substituted by one or more amine groups.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Estructura 3D

Objetivos asociados (humanos)

HT-29 (80576 Activities)

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T-24 (2342 Activities)

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A549 (127892 Activities)

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MDA-MB-231 (73002 Activities)

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RAD52 Tchem DNA repair protein RAD52 homolog (856 Activities)

Discover Target: RAD52

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Objetivos asociados (no humanos)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

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Staphylococcus aureus (210822 Activities)

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Leishmania amazonensis (3813 Activities)

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Leishmania donovani (89745 Activities)

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rep Replicase polyprotein 1ab (378 Activities)

Discover Target: rep

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SARS-CoV-2 (38078 Activities)

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Vero C1008 (1716 Activities)

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Mecanismos de acción

Certificados (CoA, COO, BSE/TSE y tabla de análisis)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

7 results found

Lot Number	Certificate Type	Fecha	Articulo
F2403386	Certificate of Analysis	Dec 12, 2025	D275881
A2206066	Certificate of Analysis	Oct 13, 2025	D275881
A2206067	Certificate of Analysis	Oct 13, 2025	D275881
A2206068	Certificate of Analysis	Oct 13, 2025	D275881
A2206069	Certificate of Analysis	Oct 13, 2025	D275881
A2206072	Certificate of Analysis	Oct 13, 2025	D275881
A2206073	Certificate of Analysis	Oct 13, 2025	D275881

Propiedades químicas y físicas

Solubilidad	Soluble in DMSO to 100 mM and in ethanol to 20 mM
Sensibilidad	Heat Sensitive
Punto de fusión (°C)	147.0 to 151.0 °C
Peso molecular	340.400 g/mol
XLogP3	5.300
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	6
Exact Mass	340.169 Da
Monoisotopic Mass	340.169 Da
Topological Polar Surface Area	49.800 Å²
Heavy Atom Count	26
Formal Charge	0
Complexity	403.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Calculadoras de soluciones

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Reseñas

Bulk & Custom Packaging Need larger quantities or custom specifications? Contact our team for a tailored quote.

N,N'-Dibencilquinazolina-2,4-diamina - ≥99% , CAS No.177355-84-9

Why this grade

Storage & shipping

Quality documents

Literature proof

Descripción general

Specifications

Documentation

📋 Safety Data Sheet (SDS)

✅ Certificate of Analysis (COA)

📊 Datasheet

🔬 Specification Sheet

Advanced Data

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

Reseñas de cliente

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