N,N′-Dimethyl-9,9′-biacridinium dinitrate - 10mM in DMSO , CAS No.2315-97-1

CAS: 2315-97-1 Cat. No.: N422744 Peso molecular: 510.51 Beilstein Registry Number: 3901768 Número EC: 219-023-4

GRADE & PURITY 10mM in DMSO

Synonyms

Bis(N-methylacridinium) Nitrate | HY-D0720 | 10,10'-Dimethyl-9,9'-biacridinium nitrate | Dimethyl biacridinium dinitrate | 10,10'-Dimethyl-9,9'-biacridinium Dinitrate [for Chemiluminescence Research] | EINECS 219-023-4 | L 6868 | Lucigenin | NSC 151912 |

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Descripción general

Reagent used for the generation of chemiluminescence in the presence of a reductant and oxygen; it is employed in numerous chemiluminescent assays. Lucigenin is specific for superoxide anion radical.

Specifications

Sinónimos

Bis(N-methylacridinium) Nitrate | HY-D0720 | 10, 10'-Dimethyl-9, 9'-biacridinium nitrate | Dimethyl biacridinium dinitrate | 10, 10'-Dimethyl-9, 9'-biacridinium Dinitrate [for Chemiluminescence Research] | EINECS 219-023-4 | L 6868 | Lucigenin | NSC 151912 |

Especificaciones y pureza

10mM in DMSO

Mecanismos bioquímicos y fisiológicos

Selective superoxide anion radical chemiluminescent probe and fluorescent chloride-sensitive indicator. Generates chemiluminescence in the presence of superoxide (O 2 - ). Detects vascular superoxide formation in vivo.

Condiciones de almacenamiento de almacenamiento

Store at -80°C

Enviado en

Dry ice packs + Cold packs

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Nombres e identificadores

• Isómeros SMILES: C[N+]1=C2C=CC=CC2=C(C3=CC=CC=C31)C4=C5C=CC=CC5=[N+](C6=CC=CC=C64)C.[N+](=O)([O-])[O-].[N+](=O)([O-])[O-]
• WGK Alemania: 3
• Peso molecular: 510.51
• Beilstein: 3901768
• Reaxy-Rn: 3901768
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3901768&ln=

Propiedades químicas y físicas

• Sensibilidad: Hygroscopic
• Punto de fusión (°C): 245-250 °C
• Peso molecular: 510.500 g/mol
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 1
• Exact Mass: 510.154 Da
• Monoisotopic Mass: 510.154 Da
• Topological Polar Surface Area: 134.000 Ų
• Heavy Atom Count: 38
• Formal Charge: 0
• Complexity: 522.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 3

XLogP3

Referencias

1. Guo Jian-Shuang, Li Juan-Juan, Wang Ze-Han, Liu Yang, Yue Yu-Xin, Li Hua-Bin, Zhao Xiu-He, Sun Yuan-Jun, Ding Ya-Hui, Ding Fei, Guo Dong-Sheng, Wang Liang, Chen Yue.  (2023)  Dual hypoxia-responsive supramolecular complex for cancer target therapy.  Nature Communications,  14  (1): (1-13).  [PMID:37704601] [10.1038/s41467-023-41388-2]

2. Weike Shaoyong, Hongli Jin, Xiao Jiang, Bocheng Xu, Yalin Liu, Yizhen Wang, Mingliang Jin.  (2023)  Benzo [a] pyrene-loaded aged polystyrene microplastics promote colonic barrier injury via oxidative stress-mediated notch signalling.  JOURNAL OF HAZARDOUS MATERIALS,      [PMID:37320903] [10.1016/j.jhazmat.2023.131820]

3. Shuai Quan, Kaixiang Ji, Fangshuo Liu, Tesfaye Hailemariam Barkae, Mohamed Ibrahim Halawa, Saima Hanif, Baohua Lou, Jianping Li, Guobao Xu.  (2022)  Chemiluminescence of lucigenin-tetracycline and its application for sensitive determination of procyanidin.  JOURNAL OF FOOD AND DRUG ANALYSIS,      [PMID:] [10.38212/2224-6614.3411]

4. Yi Wang, Chengpei Du, Ze Liu, Kanglin Pei, Yan Zhang, Wenjing Qi.  (2022)  Chemiluminescence “turn-on” detection of tyrosinase activity via in situ generation of dopamine based on a lucigenin and riboflavin system.  NEW JOURNAL OF CHEMISTRY,  46  (9): (4156-4161).  [PMID:] [10.1039/D1NJ05628J]

5. Xiaojie Chai, Yan Cui, Wencai Xu, Lingce Kong, Yanjun Zuo, Ling Yuan, Wenming Chen.  (2020)  Degradation of malathion in the solution of acetyl peroxyborate activated by carbonate: Products, kinetics and mechanism.  JOURNAL OF HAZARDOUS MATERIALS,      [PMID:33338811] [10.1016/j.jhazmat.2020.124808]

6. Huijuan Yu, Wen-Chao Geng, Zhe Zheng, Jie Gao, Dong-Sheng Guo, Yuefei Wang.  (2019)  Facile Fluorescence Monitoring of Gut Microbial Metabolite Trimethylamine N-oxide via Molecular Recognition of Guanidinium-Modified Calixarene.  Theranostics,      [PMID:31367245] [10.7150/thno.33459]

7. Di Wu, Yi Wang, Wenjing Qi, Jianyang Xu, Kanglin Pei, Lingyan Ma, Lin Qi.  (2024)  Long-lasting chemiluminescence of lucigenin/p-aminophenol system for detection of p-aminophenol in environmental water.  DYES AND PIGMENTS,      [PMID:] [10.1016/j.dyepig.2024.111959]

8. Weike Shaoyong, Lu Sun, Yujie Gan, Hongli Jin, Wusu Wang, Lin Yin, Yizhen Wang, Mingliang Jin.  (2024)  Sight of Aged Microplastics Adsorbing Heavy Metal Exacerbated Intestinal Injury: A Mechanistic Study of Autophagy-Mediated Toxicity Response.  ACS Nano,      [PMID:39392295] [10.1021/acsnano.4c08737]

9. Zhenting Ma, Liang Fan, Xia Zhao, Hongfeng Huang.  (2025)  Development and evaluation of fluorescent optical fiber sensors for chloride ion measurement in actual mortar pore solutions.  MEASUREMENT,      [PMID:] [10.1016/j.measurement.2025.117554]