GRADE & PURITY ≥97%

Synonyms

OGP | n-octyl-.beta.-d-glucopyranoside | (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-(octyloxy)oxane-3,4,5-triol | AKOS015919434 | NCGC00385963-01!(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-octoxyoxane-3,4,5-triol | n-Octyl glucoside | 1-Octyl beta-D-glucoside | B-Oct

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Descripción general

Usually used as Non-ionic, dialyzable detergent for the solubilization and isolation of membrane proteins,and has been shown to increase the resolution of proteins in 2D gels.

Octyl-beta-Glucoside is a nonionic detergent that has been widely used for membrane protein solubilization.
• A low-molecular weight, nonionic detergent
• Effective for membrane protein solubilization
• Less stable and less commonly used than octylthioglucoside (OTG)
• Can be removed from solution by dialysis
• Optically clear; low absorbance at 280nm

Specifications

Sinónimos

OGP | n-octyl-.beta.-d-glucopyranoside | (2R, 3S, 4S, 5R, 6R)-2-(hydroxymethyl)-6-(octyloxy)oxane-3, 4, 5-triol | AKOS015919434 | NCGC00385963-01!(2R, 3S, 4S, 5R, 6R)-2-(hydroxymethyl)-6-octoxyoxane-3, 4, 5-triol | n-Octyl glucoside | 1-Octyl beta-D-glucoside | B-Oct

Especificaciones y pureza

≥97%

Mecanismos bioquímicos y fisiológicos

Non-ionic detergent. Solubilizes membrane-bound proteins. Permeabilizes cell membranes of paraformaldehyde fixed cells. Forms self-assembled nanostructures in water.

Condiciones de almacenamiento de almacenamiento

Store at -20°C

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureza

≥97%

Nombres e identificadores

• Sonrisas canónicas: CCCCCCCCOC1C(C(C(C(O1)CO)O)O)O
• IUPAC Name: (2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-octoxyoxane-3,4,5-triol
• InChIKey: HEGSGKPQLMEBJL-RKQHYHRCSA-N
• INCHI: 1S/C14H28O6/c1-2-3-4-5-6-7-8-19-14-13(18)12(17)11(16)10(9-15)20-14/h10-18H,2-9H2,1H3/t10-,11-,12+,13-,14-/m1/s1
• Isómeros SMILES: CCCCCCCCO[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O
• Peso molecular: 292.37
• Beilstein: 17(5)7,38
• Reaxy-Rn: 25301480
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=25301480&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Lipids and lipid-like molecules
    • Clase Fatty Acyls
      • Subclass Fatty acyl glycosides

• Kingdom: Organic compounds
• Superclass: Lipids and lipid-like molecules
• Clase: Fatty Acyls
• Subclass: Fatty acyl glycosides
• Intermediate Tree Nodes: Not available
• Direct Parent: Fatty acyl glycosides of mono- and disaccharides
• Alternative Parents: Hexoses Alkyl glycosides O-glycosyl compounds Oxanes Secondary alcohols Polyols Oxacyclic compounds Acetals Primary alcohols Hydrocarbon derivatives
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: Fatty acyl glycoside of mono- or disaccharide - Alkyl glycoside - Hexose monosaccharide - Glycosyl compound - O-glycosyl compound - Monosaccharide - Oxane - Secondary alcohol - Acetal - Organoheterocyclic compound - Oxacycle - Polyol - Organooxygen compound - Primary alcohol - Hydrocarbon derivative - Organic oxygen compound - Alcohol - Aliphatic heteromonocyclic compound
• Descripción: This compound belongs to the class of organic compounds known as fatty acyl glycosides of mono- and disaccharides. These are compounds composed of a mono- or disaccharide moiety linked to one hydroxyl group of a fatty alcohol or of a phosphorylated alcohol (phosphoprenols), a hydroxy fatty acid or to one carboxyl group of a fatty acid (ester linkage) or to an amino alcohol.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Objetivos asociados (no humanos)

lgtC Alpha 1,4 galactosyltransferase (29 Activities)

Discover Target: lgtC

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

waaC Lipopolysaccharide heptosyltransferase 1 (62 Activities)

Discover Target: waaC

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de acción

Propiedades químicas y físicas

• Solubilidad: Soluble in water; Soluble in Methanol
• Sensibilidad: Hygroscopic
• Rotación específica [α]: -27° (C=1,MeOH)
• Punto de fusión (°C): 105°C
• Peso molecular: 292.370 g/mol
• XLogP3: 1.400
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 9
• Exact Mass: 292.189 Da
• Monoisotopic Mass: 292.189 Da
• Topological Polar Surface Area: 99.400 Ų
• Heavy Atom Count: 20
• Formal Charge: 0
• Complexity: 250.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 5
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Referencias

1. Fei Liu, Yayun Qin, Yuwen Huang, Pan Gao, Jingzhen Li, Shanshan Yu, Danna Jia, Xiang Chen, Yuexia Lv, Jiayi Tu, Kui Sun, Yunqiao Han, James Reilly, Xinhua Shu, Qunwei Lu, Zhaohui Tang, Chengqi Xu, Daji Luo, Mugen Liu.  (2022)  Rod genesis driven by mafba in an nrl knockout zebrafish model with altered photoreceptor composition and progressive retinal degeneration.  PLoS Genetics,  18  (3): (e1009841).  [PMID:35245286] [10.1371/journal.pgen.1009841]

2. Zhang Peng, Wang Junqian, Ding Xuanwei, Lin Jun, Jiang Hao, Zhou Hongjun, Lu Yuan.  (2019)  Exploration of the Tolerance Ability of a Cell-Free Biosynthesis System to Toxic Substances.  APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY,  189  (4): (1096-1107).  [PMID:31161383] [10.1007/s12010-019-03039-5]

3. Zhixia Liang, Yanbin Yun, Manxiang Wang, Guicheng Liu, Peng Lu, Woochul Yang, Chunli Li.  (2019)  Performance evaluation of interfacial polymerisation-fabricated aquaporin-based biomimetic membranes in forward osmosis.  RSC Advances,  9  (19): (10715-10726).  [PMID:35515303] [10.1039/C9RA00787C]

4. Pingping Meng, Shubo Deng, Ayiguli Maimaiti, Bin Wang, Jun Huang, Yujue Wang, Ian T. Cousins, Gang Yu.  (2018)  Efficient removal of perfluorooctane sulfonate from aqueous film-forming foam solution by aeration-foam collection.  CHEMOSPHERE,      [PMID:29625315] [10.1016/j.chemosphere.2018.03.183]

5. Yueyue Li, Yujia Zhai, Bing Fu, Yuanlin He, Ying Feng, Fang Ma, Haojie Lu.  (2024)  A comprehensive N-glycome map of porcine sperm membrane before and after capacitation.  CARBOHYDRATE POLYMERS,      [PMID:38616102] [10.1016/j.carbpol.2024.122084]

6. Jiaoming Dong, Yu Li, Xiumei Mo.  (2012)  The study of a new detergent (octyl-glucopyranoside) for decellularizing porcine pericardium as tissue engineering scaffold.  JOURNAL OF SURGICAL RESEARCH,      [PMID:23267763] [10.1016/j.jss.2012.11.047]