N-Stearoyl Phytosphingosine - ≥98% , CAS No.34354-88-6

CAS: 34354-88-6 Cat. No.: N339996 Peso molecular: 583.97 Número EC: 812-962-6

GRADE & PURITY ≥98%

Synonyms

N-18:0 Phytosphingosine, N-stearoyl 4-hydroxysphinganine (Saccharomyces Cerevisiae), powder | JNH Ato-Care Super Barried ATO-Serum | Cer(t18:0/18:0) | N-stearoylphytosphingosine | N-STEAROYL-PHYTOSPHINGOSINE | N-[(1S,2S,3R)-2,3-Dihydroxy-1-(hydroxymethyl)

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Descripción general

N-Stearoyl phytosphingosine is an intercellular lipid that benefits skin hydration and protects against SLS irritation. N-Stearoyl phytosphingosine has also been shown to to inhibit expression of IL-4, TNF-α, and transcription factors, NF-κB and c-jun, in histamine-stimulated skin tissues.

Specifications

Sinónimos

N-18:0 Phytosphingosine, N-stearoyl 4-hydroxysphinganine (Saccharomyces Cerevisiae), powder | JNH Ato-Care Super Barried ATO-Serum | Cer(t18:0/18:0) | N-stearoylphytosphingosine | N-STEAROYL-PHYTOSPHINGOSINE | N-[(1S, 2S, 3R)-2, 3-Dihydroxy-1-(hydroxymethyl)

Especificaciones y pureza

≥98%

Mecanismos bioquímicos y fisiológicos

N-stearoylphytosphingosine is an intercellular lipid that has been found to inhibit the expression of the allergic cytokines IL-4 and TNF-α. The stratum corneum (SC) is the uppermost layer of the epidermis and consists of seven different types of ceramide

Condiciones de almacenamiento de almacenamiento

Store at -20°C

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Pureza

≥98%

Nombres e identificadores

• Pubchem Sid: 488196412
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488196412
• Sonrisas canónicas: CCCCCCCCCCCCCCCCCC(=O)NC(CO)C(C(CCCCCCCCCCCCCC)O)O
• IUPAC Name: N-[(2S,3S,4R)-1,3,4-trihydroxyoctadecan-2-yl]octadecanamide
• InChIKey: IEZRNEGTKRQRFV-LFBNJJMOSA-N
• INCHI: 1S/C36H73NO4/c1-3-5-7-9-11-13-15-17-18-19-21-23-25-27-29-31-35(40)37-33(32-38)36(41)34(39)30-28-26-24-22-20-16-14-12-10-8-6-4-2/h33-34,36,38-39,41H,3-32H2,1-2H3,(H,37,40)/t33-,34+,36-/m0/s1
• Isómeros SMILES: CCCCCCCCCCCCCCCCCC(=O)N[C@@H](CO)[C@@H]([C@@H](CCCCCCCCCCCCCC)O)O
• Peso molecular: 583.97
• Reaxy-Rn: 2341383
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2341383&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Lipids and lipid-like molecules
    • Clase Sphingolipids
      • Subclass Ceramides

• Kingdom: Organic compounds
• Superclass: Lipids and lipid-like molecules
• Clase: Sphingolipids
• Subclass: Ceramides
• Intermediate Tree Nodes: Not available
• Direct Parent: Phytoceramides
• Alternative Parents: N-acyl amines Secondary carboxylic acid amides Secondary alcohols Polyols Primary alcohols Organopnictogen compounds Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: N-acyl-4-hydroxysphinganine - Fatty amide - N-acyl-amine - Fatty acyl - Carboxamide group - Secondary alcohol - Secondary carboxylic acid amide - Carboxylic acid derivative - Polyol - Organic oxide - Organooxygen compound - Organonitrogen compound - Organopnictogen compound - Organic oxygen compound - Alcohol - Organic nitrogen compound - Carbonyl group - Primary alcohol - Hydrocarbon derivative - Aliphatic acyclic compound
• Descripción: This compound belongs to the class of organic compounds known as phytoceramides. These are n-acylated 4-hydroxysphinganine.
• External Descriptors: N-acyl-4-hydroxysphinganines (phytoceramides)

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Solubilidad: Soluble in chloroform/ methanol, 1:1 (warm).
• Sensibilidad: Moisture sensitive
• Índice de refracción: n20D1.48 (Predicted)
• Punto de ebullición (°C): ~721.4° C at 760 mmHg (Predicted)
• Peso molecular: 584.000 g/mol
• XLogP3: 13.300
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 33
• Exact Mass: 583.554 Da
• Monoisotopic Mass: 583.554 Da
• Topological Polar Surface Area: 89.800 Ų
• Heavy Atom Count: 41
• Formal Charge: 0
• Complexity: 530.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 3
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1