N-Succinimidyl 4-Maleimidobutyrate [Cross-linking Reagent] - ≥98%(HPLC) , CAS No.80307-12-6

CAS: 80307-12-6 Cat. No.: N159716 Peso molecular: 280.24 Número EC: 625-693-2

GRADE & PURITY ≥98%(HPLC)

Synonyms

PROPARACAINE [VANDF] | MFCD00036817 | (GMBS);4-Maleimidobutyric acid NHS | EN300-105191 | Surpur | BP-31232 | FT-0604086 | N-y-maleimidobutyryloxy succinimide ester | 1H-Pyrrole-1-butanoic acid, 2,5-dihydro-2,5-dioxo-, 2,5-dioxo-1-pyrrolidinyl ester | GMB

Storage

Protected from light,Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Specifications

Sinónimos

PROPARACAINE [VANDF] | MFCD00036817 | (GMBS);4-Maleimidobutyric acid NHS | EN300-105191 | Surpur | BP-31232 | FT-0604086 | N-y-maleimidobutyryloxy succinimide ester | 1H-Pyrrole-1-butanoic acid, 2, 5-dihydro-2, 5-dioxo-, 2, 5-dioxo-1-pyrrolidinyl ester | GMB

Especificaciones y pureza

≥98%(HPLC)

Condiciones de almacenamiento de almacenamiento

Protected from light, Store at -20°C, Argon charged

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Pureza

≥98%(HPLC)

Nombres e identificadores

• Pubchem Sid: 504757019
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/504757019
• Sonrisas canónicas: C1CC(=O)N(C1=O)OC(=O)CCCN2C(=O)C=CC2=O
• IUPAC Name: (2,5-dioxopyrrolidin-1-yl) 4-(2,5-dioxopyrrol-1-yl)butanoate
• InChIKey: PVGATNRYUYNBHO-UHFFFAOYSA-N
• INCHI: 1S/C12H12N2O6/c15-8-3-4-9(16)13(8)7-1-2-12(19)20-14-10(17)5-6-11(14)18/h3-4H,1-2,5-7H2
• Isómeros SMILES: C1CC(=O)N(C1=O)OC(=O)CCCN2C(=O)C=CC2=O
• Peso molecular: 280.24
• Reaxy-Rn: 6427689
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=6427689&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Clase Pyrrolidines
      • Subclass Pyrrolidones

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Clase: Pyrrolidines
• Subclass: Pyrrolidones
• Intermediate Tree Nodes: Not available
• Direct Parent: Maleimides
• Alternative Parents: Pyrrolidine-2-ones N-substituted carboxylic acid imides Pyrrolines Dicarboximides Lactams Carboxylic acid salts Monocarboxylic acids and derivatives Azacyclic compounds Organopnictogen compounds Organonitrogen compounds Organic salts Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: Maleimide - Carboxylic acid imide, n-substituted - 2-pyrrolidone - Carboxylic acid imide - Dicarboximide - Pyrroline - Carboxylic acid salt - Lactam - Carboxylic acid derivative - Monocarboxylic acid or derivatives - Azacycle - Organonitrogen compound - Hydrocarbon derivative - Carbonyl group - Organic oxide - Organopnictogen compound - Organic oxygen compound - Organic nitrogen compound - Organooxygen compound - Organic salt - Aliphatic heteromonocyclic compound
• Descripción: This compound belongs to the class of organic compounds known as maleimides. These are compounds containing a 2,5-pyrroledione moiety.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propiedades químicas y físicas

• Sensibilidad: Light Sensitive,Moisture Sensitive,Heat Sensitive
• Punto de fusión (°C): 130 °C
• Peso molecular: 280.230 g/mol
• XLogP3: -1.200
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 6
• Exact Mass: 280.07 Da
• Monoisotopic Mass: 280.07 Da
• Topological Polar Surface Area: 101.000 Ų
• Heavy Atom Count: 20
• Formal Charge: 0
• Complexity: 490.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Referencias

1. Sha Qiuyue, Fei Jian, Tu Chang, Liu Bi-Feng, Hu Zhaoyu, Liu Xin.  (2022)  A universal strategy of glyconanoparticle preparation using a bifunctional linker for lectin sensing and cell imaging.  MICROCHIMICA ACTA,  189  (4): (1-11).  [PMID:35332420] [10.1007/s00604-022-05220-w]

2. Bohan Yin, Hongrong Yang, Mo Yang.  (2022)  Integrating Soft Hydrogel with Nanostructures Reinforces Stem Cell Adhesion and Differentiation.  Journal of Composites Science,  6  (1): (19).  [PMID:] [10.3390/jcs6010019]

3. Xu Wang, Tao Han, Xiwei Jiang, Sicen Lin, Xinyu Lou, Xianbao Shi, Zhenguo Cheng, Zhonggui He, Hongzan Sun, Funan Liu, Jin Sun, Mengchi Sun.  (2024)  Bimetallic nanodot-adenovirus chimera for cancer theranostics via cooperativity of autophagy and ferroptosis.  Cell Reports Physical Science,      [PMID:] [10.1016/j.xcrp.2024.102221]