Determine the necessary mass, volume, or concentration for preparing a solution.
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
≥95% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C,Argon charged Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 16 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
N-tert-butyl-α-phenylnitro?ne (PBN) is a commonly used free-radical spin trap. It has been shown to reduce the number of emboli-induced cerebral microinfarctions in the rabbit cortex and prevent neoplasia by its radical scavenging activity and its ability to inhibit cyclooxygenase-2 activity. Reported to inhibit the induction of nitric oxide synthase (iNOS), thereby preventing the overproduction of nitric oxide (NO). PBN in a dose of 100 mg/kg i.p. reduced necrosis of the substantia nigra, pars reticulate in flurothyl-induced status epilepticus in rats. It protects against some types of post-trauma epileptogenic events in an animal model of epilepsy.The lethal dose of PBN in rats was found to be approximately 100 mg/100 g body weight (0.564 mmol/100? g).
A Cox-2 inhibitor.
| Pubchem Sid | 504759662 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504759662 |
| Sonrisas canónicas | CC(C)(C)[N+](=CC1=CC=CC=C1)[O-] |
| IUPAC Name | N-tert-butyl-1-phenylmethanimine oxide |
| InChIKey | IYSYLWYGCWTJSG-XFXZXTDPSA-N |
| INCHI | 1S/C11H15NO/c1-11(2,3)12(13)9-10-7-5-4-6-8-10/h4-9H,1-3H3/b12-9- |
| Isómeros SMILES | CC(C)(C)/[N+](=C/C1=CC=CC=C1)/[O-] |
| WGK Alemania | 3 |
| RTECS | TX1760000 |
| Peso molecular | 177.24 |
| Beilstein | 2044028 |
| Reaxy-Rn | 2044028 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=2044028&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Taxonomy Tree
| Kingdom | Organic compounds |
|---|---|
| Superclass | Benzenoids |
| Clase | Benzene and substituted derivatives |
| Subclass | Not available |
| Intermediate Tree Nodes | Not available |
| Direct Parent | Benzene and substituted derivatives |
| Alternative Parents | Shiff bases Nitrones Propargyl-type 1,3-dipolar organic compounds Organopnictogen compounds Organic oxides Hydrocarbon derivatives |
| Molecular Framework | Aromatic homomonocyclic compounds |
| Substituents | Monocyclic benzene moiety - Shiff base - Nitrone - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Allyl-type 1,3-dipolar organic compound - Organic nitrogen compound - Organic oxygen compound - Organopnictogen compound - Organic oxide - Hydrocarbon derivative - Organonitrogen compound - Aromatic homomonocyclic compound |
| Descripción | This compound belongs to the class of organic compounds known as benzene and substituted derivatives. These are aromatic compounds containing one monocyclic ring system consisting of benzene. |
| External Descriptors | Not available |
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Fecha | Articulo |
|---|---|---|---|
| Certificate of Analysis | Apr 29, 2026 | B100838 | |
| Certificate of Analysis | Sep 22, 2025 | B100838 | |
| Certificate of Analysis | May 20, 2025 | B100838 | |
| Certificate of Analysis | Apr 02, 2025 | B100838 | |
| Certificate of Analysis | Apr 02, 2025 | B100838 | |
| Certificate of Analysis | Apr 02, 2025 | B100838 | |
| Certificate of Analysis | Feb 06, 2024 | B100838 | |
| Certificate of Analysis | Feb 06, 2024 | B100838 | |
| Certificate of Analysis | Jun 06, 2022 | B100838 | |
| Certificate of Analysis | Mar 14, 2022 | B100838 |
| Solubilidad | Soluble in DMSO (10 mg/ml), chloroform (50 mg/ml), and water (20 mg/ml). |
|---|---|
| Sensibilidad | Air Sensitive |
| Punto de fusión (°C) | 72-75°C |
| Peso molecular | 177.240 g/mol |
| XLogP3 | 1.300 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 1 |
| Rotatable Bond Count | 2 |
| Exact Mass | 177.115 Da |
| Monoisotopic Mass | 177.115 Da |
| Topological Polar Surface Area | 28.800 Ų |
| Heavy Atom Count | 13 |
| Formal Charge | 0 |
| Complexity | 185.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 1 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 1 |
| Covalently-Bonded Unit Count | 1 |
| 1. Zening Zhang, Peng Deng, Yang Chen, Zhiyong He, Fang Qin, Qiuming Chen, Zhaojun Wang, Jie Chen, Maomao Zeng, Hongyang Pan. (2023) Exploration of the synergistic inhibition of 4-methylimidazole and 5-hydroxymethylfurfural in caramel colors by amino acid combinations and potential mechanisms. Food Bioscience, [PMID:] [10.1016/j.fbio.2023.103471] |
| 2. Ming Yuan, Dayun Huang, Zefeng Wang, Xin Chen, Minghua Yang. (2022) Synthesis of ultra-high molecular weight poly(methyl methacrylate) with hydrosilane as initiator. Materials Today Communications, [PMID:] [10.1016/j.mtcomm.2022.104927] |
| 3. Hao-Xiang Gao, Nan Chen, Qiang He, Bi Shi, Zhi-Long Yu, Wei-Cai Zeng. (2022) Effects of Ligustrum robustum (Rxob.) Blume extract on the quality of peanut and palm oils during storage and frying process. JOURNAL OF FOOD SCIENCE, 87 (10): (4504-4521). [PMID:36124403] [10.1111/1750-3841.16311] |
| 4. Yingjie Ma, Hairong Huang, Yan Zhang, Feng Li, Bei Gan, Qiang Yu, Jianhua Xie, Yi Chen. (2022) Soluble dietary fiber from tea residues with inhibitory effects against acrylamide and 5-hydroxymethylfurfural formation in biscuits: The role of bound polyphenols. FOOD RESEARCH INTERNATIONAL, [PMID:35940761] [10.1016/j.foodres.2022.111595] |
| 5. Zhou Yulan, Liao Wanfeng, Ni Xiuyuan. (2020) Cationic Photopolymerization Initiated by a Photocatalytic Complex Sensitive to Visible Light at 520 nm. CATALYSIS LETTERS, 151 (6): (1766-1775). [PMID:] [10.1007/s10562-020-03437-z] |
| 6. Wanfeng Liao, Xiuyuan Ni, Yulan Zhou. (2018) Cationic and free radical polymerization initiated by a visible-light sensitive complex based on the photocatalytic decarboxylation of carboxylic acid. JOURNAL OF CATALYSIS, [PMID:] [10.1016/j.jcat.2018.03.005] |
| 7. Yongxi Deng, Kecheng Zhu, Wenjun Jiang, Yixuan Liu, Linyang Xie, Fuhao Liu, Kangjie Yang, Yuanren Jiang, Hanzhong Jia. (2024) Novel Chemical Routes for Carbon Dioxide and Methane Production from Lignin Photodegradation: The Role of Environmental Free Radicals. ENVIRONMENTAL SCIENCE & TECHNOLOGY, [PMID:39205644] [10.1021/acs.est.4c03414] |
| 8. Nuo Cheng, Fu Deng, Jinlong Wang, Longfeng Hu, Jiaxuan Yang, Shu Jiang, Hesong Wang, Xiaofei Ma, Lei Zhao, Guibai Li, Han Zhang, Heng Liang. (2024) Simultaneous alkali recovery, coagulant recycling and organics removal from textile wastewater via membrane electrochemical system. SEPARATION AND PURIFICATION TECHNOLOGY, [PMID:] [10.1016/j.seppur.2024.129448] |
| 9. Zhaofen Xu, Lingfang Tang, Yuanyi Zhou, Gang Lu, Haojie Dong, Mingshan Zhu. (2024) Utilizing the immanent chloride ions in wastewater for reactive chlorine species photogeneration towards effective ammonia nitrogen removal. CHEMICAL ENGINEERING JOURNAL, [PMID:] [10.1016/j.cej.2024.152589] |
| 10. Luo Xiongfei, Liu Xue, Guo Hongda, Li Ruiping, Wang Min, Li Xiaotong, Li Shujun, Liu Shouxin, Li Jian, Strehmel Veronika, Wang Qunying, Yilmaz Gorkem, Matyjaszewski Krzysztof, Strehmel Bernd, Chen Zhijun. (2025) Biomass-derived carbon dots for the initiation of conventional radical and ATRP-based photopolymerization processes. Nature Protocols, [PMID:40760038] [10.1038/s41596-025-01210-3] |
| 11. Yicheng Fan, Xiuyuan Ni, Wenbin Fu. (2025) Photocatalyzed ring-opening polymerization of ε-caprolactone. Catalysis Science & Technology, [PMID:] [10.1039/D5CY00845J] |
| 12. Libin Sun, Zhe Huang, Junguo Wang, Dianyu Yu, Liqi Wang. (2024) Effect of deodorization conditions on fatty acid profile, oxidation products, and lipid-derived free radicals of soybean oil. FOOD CHEMISTRY, [PMID:38788646] [10.1016/j.foodchem.2024.139656] |
| 13. Peng Deng, Qifan Wang, Shengfang Wu, Xiuwen Zhou, Fatih Oz, Qiuming Chen, Zhaojun Wang, Zhiyong He, Jie Chen, Maomao Zeng. (2025) Synergistic effect of spice extracts on multiple hazards formation and sensory markers in beef flavoring. Food Bioscience, [PMID:] [10.1016/j.fbio.2025.106099] |
| 14. Yu-Dong Shan, Yu-Le Wang, Qing He, Yi-Fang Lu, Song-Hai Wu, Yong Liu, Xu Han. (2025) Selective Photooxidation of Cyclohexane to KA-Oil by Mo-Doped Mesoporous TiO2 and the Role of Electron-Shuttling Quinones. ACS Catalysis, [PMID:] [10.1021/acscatal.5c01245] |
| 15. Ying Luo, Jie Xu, Ying-Chen Fan, Zong-Han Wang, Yuan-Yuan Hu, De-Yang Li, Yu-Xin Liu, Da-Yong Zhou. (2025) Effect of lipid oxidation on the color deterioration of ready-to-eat oysters: Discussion based on the model system. FOOD CHEMISTRY, [PMID:41218311] [10.1016/j.foodchem.2025.147024] |
| 16. Yuan Ming, Han Xiaofang, Zhang Zekai, Wang Ruijia, Guo Shengrong. (2025) Synthesis of ultra-high molecular weight poly(methyl methacrylate) initiated by the combination of copper nanopowder with organic halides. BMC Chemistry, 19 (1): (223). [PMID:40713622] [10.1186/s13065-025-01597-w] |