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Nebicapone (BIA 3-202), a reversible catechol-O-methyltransferase (COMT) inhibitor, is mainly metabolized by glucuronidation. Nebicapone is mainly peripherally acting inhibitor that decreases the biotransformation of L-DOPA to 3-O-methyl-DOPA by inhibition of COMT , and it is potential for the treatment of Parkinson's disease.
Form:Solid
| CAS | 274925-86-9 |
|---|---|
| Sinónimos | Ethanone, 1-(3,4-dihydroxy-5-nitrophenyl)-2-phenyl- | BIA 3-202 | 1-(3,4-dihydroxy-5-nitro-phenyl)-2-phenyl-ethanone | Q21547145 | SCHEMBL132167 | NM2KXJ990T | DTXSID30181912 | 1-(3,4-dihydroxy-5-nitrophenyl)-2-phenylethanone | BDBM50108878 | 3-NITRO-5-PH |
| Especificaciones y pureza | Moligand™,≥99% |
| Condiciones de almacenamiento de almacenamiento | Protected from light,Store at -20°C,Desiccated |
| Enviado en | Ice chest + Ice pads |
| Product Description | Nebicapone (BIA 3-202), a reversible catechol-O-methyltransferase (COMT) inhibitor, is mainly metabolized by glucuronidation. Nebicapone is mainly peripherally acting inhibitor that decreases the biotransformation of L-DOPA to 3-O-methyl-DOPA by inhibition of COMT , and it is potential for the treatment of Parkinson's disease. Form:Solid |
| Solubilidad | DMSO : ≥ 100 mg/mL (365.98 mM) |
| PubChem CID | 9838389 |
| Fórmula molecular | C14H11NO5 |
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