≥95% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 1 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Neoantimycin is a macrocyclic antibiotic isolated from|Streptomyces|bacteria. The mechanism of action of Neoantimycin is undescribed in the literature. A closely related compound described as an oxidized-type neoantimycin, prunustatin A, is demonstrated to downregulate grp78 transcription and suppress the expression of the GRP 78 molecular chaperone. This suppression affects the role of GRP 78 in promoting protein folding at the endoplasmic reticulum (ER), and suppresses the pro-resistance enhancement of ER stress response by chemotherapy-resistant tumors. The close structural kinship between prunustatin A and Neoantimycin suggests a similar mechanism of action for Neoantimycin toxicity.
| Sonrisas canónicas | CCC(C)C1C(=O)OC(C(C(=O)OC(C(=O)OC(C(C(C(=O)O1)(C)C)O)CC2=CC=CC=C2)C(C)C)NC(=O)C3=C(C(=CC=C3)NC=O)O)C |
|---|---|
| IUPAC Name | N-(15-benzyl-10-butan-2-yl-14-hydroxy-7,13,13-trimethyl-2,5,9,12-tetraoxo-3-propan-2-yl-1,4,8,11-tetraoxacyclopentadec-6-yl)-3-formamido-2-hydroxybenzamide |
| InChIKey | JIJATTFJYJZEBT-UHFFFAOYSA-N |
| INCHI | 1S/C36H46N2O12/c1-8-20(4)29-34(45)47-21(5)26(38-31(42)23-15-12-16-24(27(23)40)37-18-39)32(43)49-28(19(2)3)33(44)48-25(17-22-13-10-9-11-14-22)30(41)36(6,7)35(46)50-29/h9-16,18-21,25-26,28-30,40-41H,8,17H2,1-7H3,(H,37,39)(H,38,42) |
| Isómeros SMILES | CCC(C)C1C(=O)OC(C(C(=O)OC(C(=O)OC(C(C(C(=O)O1)(C)C)O)CC2=CC=CC=C2)C(C)C)NC(=O)C3=C(C(=CC=C3)NC=O)O)C |
| Peso molecular | 698.76 |
| Reaxy-Rn | 3116939 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3116939&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
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| Lot Number | Certificate Type | Fecha | Articulo |
|---|---|---|---|
 D23031217 | Certificate of Analysis | Jan 21, 2026 | N329566 |
| D23031235 | Certificate of Analysis | Jan 21, 2026 | N329566 |
| I2222340 | Certificate of Analysis | Jul 10, 2025 | N329566 |
| Solubilidad | Soluble in ethanol, methanol, DMF, and DMSO. |
|---|---|
| Índice de refracción | n20D1.58 (Predicted) |
| Punto de ebullición (°C) | 930.35° C at 760 mmHg (Predicted) |
| 1. Ou Panpan, Wu Jiawen, Lin Yu, Tan Xuecai, Wu Yeyu, Chen Zhifan, Wei Fucun, Huang Kejing. (2022) Flexible photoelectrochemical sensor for highly sensitive chloramphenicol detection based on M-TiO2-CdTe QDs/CdS QDs composite. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 414 (6): (2065-2078). [PMID:34984509] [10.1007/s00216-021-03840-4] |
