NF 023 hydrate - ≥94% , CAS No.104869-31-0

CAS: 104869-31-0 Cat. No.: N275685 Peso molecular: 1388.02

GRADE & PURITY ≥94%

Synonyms

PUBCHEM_53249227 | NF 023 | 1,3,5-Naphthalenetrisulfonicacid, 8,8'-[carbonylbis(imino-3,1-phenylenecarbonylimino)]bis-, sodium salt(1:6) | NF023 hexasodium | DTXSID30692912 | AKOS040764301

Storage

Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

Descripción general

Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

Specifications

Sinónimos

PUBCHEM_53249227 | NF 023 | 1, 3, 5-Naphthalenetrisulfonicacid, 8, 8'-[carbonylbis(imino-3, 1-phenylenecarbonylimino)]bis-, sodium salt(1:6) | NF023 hexasodium | DTXSID30692912 | AKOS040764301

Especificaciones y pureza

≥94%

Mecanismos bioquímicos y fisiológicos

Suramin analog and subtype-selective competitive antagonist at P2X 1 receptors (IC 50 values are 0.21, 28.9, >50 and >100 μM for human P2X 1 , P2X 3 , P2X 2 , and P2X 4 -mediated responses, respectively).

Condiciones de almacenamiento de almacenamiento

Store at -20°C, Desiccated

Enviado en

Ice chest + Ice pads

Este producto requiere envío en cadena de frío. Los servicios terrestres y otros servicios económicos no están disponibles.

Tipo de acción

ANTAGONIST

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureza

≥94%

Nombres e identificadores

• Sonrisas canónicas: C1=CC(=CC(=C1)NC(=O)NC2=CC=CC(=C2)C(=O)NC3=C4C(=CC(=CC4=C(C=C3)S(=O)(=O)O)S(=O)(=O)O)S(=O)(=O)O)C(=O)NC5=C6C(=CC(=CC6=C(C=C5)S(=O)(=O)O)S(=O)(=O)O)S(=O)(=O)O.[Na].[Na].[Na].[Na].[Na].[Na]
• InChIKey: GKOOKWDOKJAVBD-UHFFFAOYSA-N
• INCHI: 1S/C35H26N4O21S6.6Na/c40-33(38-25-7-9-27(63(49,50)51)23-13-21(61(43,44)45)15-29(31(23)25)65(55,56)57)17-3-1-5-19(11-17)36-35(42)37-20-6-2-4-18(12-20)34(41)39-26-8-10-28(64(52,53)54)24-14-22(62(46,47)48)16-30(32(24)26)66(58,59)60;;;;;;/h1-16H,(H,38,40)(H,39,41)(H2,36,37,42)(H,43,44,45)(H,46,47,48)(H,49,50,51)(H,52,53,54)(H,55,56,57)(H,58,59,60)
• Isómeros SMILES: C1=CC(=CC(=C1)NC(=O)NC2=CC=CC(=C2)C(=O)NC3=C4C(=CC(=CC4=C(C=C3)S(=O)(=O)O)S(=O)(=O)O)S(=O)(=O)O)C(=O)NC5=C6C(=CC(=CC6=C(C=C5)S(=O)(=O)O)S(=O)(=O)O)S(=O)(=O)O.[Na].[Na].[Na].[Na].[Na].[Na]
• Peso molecular: 1388.02
• Reaxy-Rn: 24212118
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=24212118&ln=

Propiedades químicas y físicas

• Solubilidad: Soluble in water to 100 mM

Referencias

1. Li Hanxiao, Dong Yingyue, Han Chunmiao, Xia Lisha, Zhang Yue, Chen Tongsheng, Wang Huamin, Xu Guoheng.  (2023)  Suramin, an antiparasitic drug, stimulates adipocyte differentiation and promotes adipogenesis.  Lipids in Health and Disease,  22  (1): (1-16).  [PMID:38093311] [10.1186/s12944-023-01980-3]